adrenosterone-5464 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the adrenosterone-5464 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
ADM adrenomedullin
ARHGAP33 Rho GTPase activating protein 33
ARHGAP44 Rho GTPase activating protein 44
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BMP1 bone morphogenetic protein 1
C22ORF46 chromosome 22 open reading frame 46
CCDC121 coiled-coil domain containing 121
CCDC22 coiled-coil domain containing 22
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEP164 centrosomal protein 164kDa
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLCN4 chloride channel, voltage-sensitive 4
CNOT2 CCR4-NOT transcription complex, subunit 2
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL13A1 collagen, type XIII, alpha 1
DMTN dematin actin binding protein
DST dystonin
ELL2 elongation factor, RNA polymerase II, 2
EN1 engrailed homeobox 1
EVA1B eva-1 homolog B (C. elegans)
FAIM2 Fas apoptotic inhibitory molecule 2
FAM120C family with sequence similarity 120C
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR4 fibroblast growth factor receptor 4
FN1 fibronectin 1
FOXA2 forkhead box A2
FOXL1 forkhead box L1
FSCN1 fascin actin-bundling protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GM2A GM2 ganglioside activator
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRIP2 glutamate receptor interacting protein 2
HNMT histamine N-methyltransferase
HOXA10 homeobox A10
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA14 interferon, alpha 14
IGFBP6 insulin-like growth factor binding protein 6
IGSF1 immunoglobulin superfamily, member 1
IRF4 interferon regulatory factor 4
IRF9 interferon regulatory factor 9
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0930 KIAA0930
LAMC2 laminin, gamma 2
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LPIN2 lipin 2
LUZP1 leucine zipper protein 1
LUZP4 leucine zipper protein 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL7A methyltransferase like 7A
NDE1 nudE neurodevelopment protein 1
NEB nebulin
NPR3 natriuretic peptide receptor 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PHF7 PHD finger protein 7
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POU4F1 POU class 4 homeobox 1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRLR prolactin receptor
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS4 regulator of G-protein signaling 4
RNF19B ring finger protein 19B
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEZ6L seizure related 6 homolog (mouse)-like
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC12A8 solute carrier family 12, member 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SOX13 SRY (sex determining region Y)-box 13
SPN sialophorin
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TM4SF1 transmembrane 4 L six family member 1
TMEM63A transmembrane protein 63A
TOP3B topoisomerase (DNA) III beta
TOX thymocyte selection-associated high mobility group box
TREM1 triggering receptor expressed on myeloid cells 1
TRIL TLR4 interactor with leucine-rich repeats
UBA7 ubiquitin-like modifier activating enzyme 7
VCAN versican
WTAP Wilms tumor 1 associated protein
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
AHDC1 AT hook, DNA binding motif, containing 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
AMPD2 adenosine monophosphate deaminase 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTBD3 BTB (POZ) domain containing 3
CAPN5 calpain 5
CCDC94 coiled-coil domain containing 94
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD83 CD83 molecule
CGREF1 cell growth regulator with EF-hand domain 1
CISH cytokine inducible SH2-containing protein
CLSPN claspin
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF16 DDB1 and CUL4 associated factor 16
DCP1A decapping mRNA 1A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAH17 dynein, axonemal, heavy chain 17
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EXOC5 exocyst complex component 5
FAM127B family with sequence similarity 127, member B
FAM86C1 family with sequence similarity 86, member C1
FBRS fibrosin
FGD6 FYVE, RhoGEF and PH domain containing 6
FGGY FGGY carbohydrate kinase domain containing
FURIN furin (paired basic amino acid cleaving enzyme)
GADD45G growth arrest and DNA-damage-inducible, gamma
GPX2 glutathione peroxidase 2
HPS4 Hermansky-Pudlak syndrome 4
IDI2-AS1 IDI2 antisense RNA 1
IL17RA interleukin 17 receptor A
IRF2BP1 interferon regulatory factor 2 binding protein 1
KAT2A K(lysine) acetyltransferase 2A
KCNK15 potassium channel, two pore domain subfamily K, member 15
KDM5C lysine (K)-specific demethylase 5C
KIFAP3 kinesin-associated protein 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIN7B lin-7 homolog B (C. elegans)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MARC1 mitochondrial amidoxime reducing component 1
MB myoglobin
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
METTL1 methyltransferase like 1
MITF microphthalmia-associated transcription factor
MMP9 matrix metallopeptidase 9
MON1B MON1 secretory trafficking family member B
MUC3A mucin 3A, cell surface associated
NPM3 nucleophosmin/nucleoplasmin 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PANX1 pannexin 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRMT7 protein arginine methyltransferase 7
PRR3 proline rich 3
RAB33B RAB33B, member RAS oncogene family
RANGRF RAN guanine nucleotide release factor
RASA2 RAS p21 protein activator 2
REEP4 receptor accessory protein 4
RNH1 ribonuclease/angiogenin inhibitor 1
RPL39L ribosomal protein L39-like
RWDD2A RWD domain containing 2A
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SETD8 SET domain containing (lysine methyltransferase) 8
SIK1 salt-inducible kinase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SPINK4 serine peptidase inhibitor, Kazal type 4
SSFA2 sperm specific antigen 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTN1 tectonic family member 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TKFC triokinase/FMN cyclase
TRAF2 TNF receptor-associated factor 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XYLT2 xylosyltransferase II
ZBTB39 zinc finger and BTB domain containing 39
ZNF205 zinc finger protein 205
ZNF212 zinc finger protein 212
ZNF273 zinc finger protein 273
ZNF639 zinc finger protein 639
ZNF668 zinc finger protein 668
ZNF74 zinc finger protein 74