adults Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

392 genes co-occuring with the biological term adults in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCY3 adenylate cyclase 3
ADD1 adducin 1 (alpha)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA2B adrenoceptor alpha 2B
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHSG alpha-2-HS-glycoprotein
AKAP10 A kinase (PRKA) anchor protein 10
ALAS2 5'-aminolevulinate synthase 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPL alkaline phosphatase, liver/bone/kidney
AMH anti-Mullerian hormone
AMY1A amylase, alpha 1A (salivary)
ANGPT2 angiopoietin 2
ANGPTL4 angiopoietin-like 4
ANKK1 ankyrin repeat and kinase domain containing 1
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARG1 arginase 1
AS3MT arsenite methyltransferase
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATRX alpha thalassemia/mental retardation syndrome X-linked
ATXN7 ataxin 7
AVPR2 arginine vasopressin receptor 2
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4A complement component 4A (Rodgers blood group)
CA6 carbonic anhydrase VI
CAMTA1 calmodulin binding transcription activator 1
CAPN10 calpain 10
CCL2 chemokine (C-C motif) ligand 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40LG CD40 ligand
CD80 CD80 molecule
CD86 CD86 molecule
CDH13 cadherin 13
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CFH complement factor H
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNR1 cannabinoid receptor 1 (brain)
CNTNAP2 contactin associated protein-like 2
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CST3 cystatin C
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYCS cytochrome c, somatic
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DEL22Q11.2 Chromosome 22q11.2 deletion syndrome, distal
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EDN1 endothelin 1
EFNB2 ephrin-B2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPHB2 EPH receptor B2
EPO erythropoietin
ESR2 estrogen receptor 2 (ER beta)
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM92B family with sequence similarity 92, member B
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCRL4 Fc receptor-like 4
FCRLA Fc receptor-like A
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF10 fibroblast growth factor 10
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FKTN fukutin
FLG filaggrin
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FNDC5 fibronectin type III domain containing 5
FOXP3 forkhead box P3
FTL ferritin, light polypeptide
FTO fat mass and obesity associated
G6PC glucose-6-phosphatase, catalytic subunit
G6PC2 glucose-6-phosphatase, catalytic, 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GATA1 GATA binding protein 1 (globin transcription factor 1)
GC group-specific component (vitamin D binding protein)
GCG glucagon
GCKR glucokinase (hexokinase 4) regulator
GGT1 gamma-glutamyltransferase 1
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GJA4 gap junction protein, alpha 4, 37kDa
GLDC glycine dehydrogenase (decarboxylating)
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPR101 G protein-coupled receptor 101
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX3 glutathione peroxidase 3
GRK4 G protein-coupled receptor kinase 4
GRM5 glutamate receptor, metabotropic 5
GRM7 glutamate receptor, metabotropic 7
GSTM1 glutathione S-transferase mu 1
HAMP hepcidin antimicrobial peptide
HAVCR1 hepatitis A virus cellular receptor 1
HBA1 hemoglobin, alpha 1
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HP haptoglobin
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IBD5 inflammatory bowel disease 5
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDE insulin-degrading enzyme
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGH immunoglobulin heavy locus
IL10 interleukin 10
IL12RB1 interleukin 12 receptor, beta 1
IL15 interleukin 15
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
IL7R interleukin 7 receptor
INS insulin
IRS1 insulin receptor substrate 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITLN1 intelectin 1 (galactofuranose binding)
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNIP4 Kv channel interacting protein 4
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KDR kinase insert domain receptor
KIAA1217 KIAA1217
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLK7 kallikrein-related peptidase 7
KMT2A lysine (K)-specific methyltransferase 2A
LBP lipopolysaccharide binding protein
LCN2 lipocalin 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LCT lactase
LEP leptin
LEPQTL1 Leptin, serum levels of
LGALS2 lectin, galactoside-binding, soluble, 2
LIFR leukemia inhibitory factor receptor alpha
LPIN1 lipin 1
LPIN2 lipin 2
LPIN3 lipin 3
LPL lipoprotein lipase
LRP2 low density lipoprotein receptor-related protein 2
LRP5 low density lipoprotein receptor-related protein 5
LTA lymphotoxin alpha
LY86 lymphocyte antigen 86
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MBNL1 muscleblind-like splicing regulator 1
MC4R melanocortin 4 receptor
MGMT O-6-methylguanine-DNA methyltransferase
MICB MHC class I polypeptide-related sequence B
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR1-1 microRNA 1-1
MIR122 microRNA 122
MIR133A1 microRNA 133a-1
MIR133A2 microRNA 133a-2
MIR133B microRNA 133b
MIR150 microRNA 150
MIR186 microRNA 186
MIR210 microRNA 210
MIR451A microRNA 451a
MIR503 microRNA 503
MKI67 marker of proliferation Ki-67
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYO18B myosin XVIIIB
NANOG Nanog homeobox
NCF4 neutrophil cytosolic factor 4, 40kDa
NELL1 NEL-like 1 (chicken)
NFIA nuclear factor I/A
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOG noggin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
NPY neuropeptide Y
NPY2R neuropeptide Y receptor Y2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTN1 netrin 1
NTSR1 neurotensin receptor 1 (high affinity)
OPRM1 opioid receptor, mu 1
OPTN optineurin
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
OTC ornithine carbamoyltransferase
OXTR oxytocin receptor
PCDH1 protocadherin 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PER2 period circadian clock 2
PEX2 peroxisomal biogenesis factor 2
PHOX2B paired-like homeobox 2b
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PKM pyruvate kinase, muscle
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAG1 pleiomorphic adenoma gene 1
PLAT plasminogen activator, tissue
PLCE1 phospholipase C, epsilon 1
PLIN1 perilipin 1
PODXL podocalyxin-like
PON1 paraoxonase 1
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PROM1 prominin 1
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTEN phosphatase and tensin homolog
PTGDR prostaglandin D2 receptor (DP)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTH1R parathyroid hormone 1 receptor
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
PYY peptide YY
RBP4 retinol binding protein 4, plasma
RELN reelin
REN renin
RET ret proto-oncogene
RETN resistin
RGS2 regulator of G-protein signaling 2
S100B S100 calcium binding protein B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA1 surfactant protein A1
SFTPB surfactant protein B
SFTPC surfactant protein C
SHBG sex hormone-binding globulin
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC38A2 solute carrier family 38, member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMN2 survival of motor neuron 2, centromeric
SOD1 superoxide dismutase 1, soluble
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOST sclerostin
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SUMO4 small ubiquitin-like modifier 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFE3 transcription factor binding to IGHM enhancer 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFR2 transferrin receptor 2
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
WWC1 WW and C2 domain containing 1
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZNF432 zinc finger protein 432