aggregation Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

459 genes co-occuring with the biological term aggregation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACHE acetylcholinesterase (Yt blood group)
ACO2 aconitase 2, mitochondrial
ACTA1 actin, alpha 1, skeletal muscle
ACYP2 acylphosphatase 2, muscle type
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCY3 adenylate cyclase 3
ADCY8 adenylate cyclase 8 (brain)
ADGRE5 adhesion G protein-coupled receptor E5
ADRA2A adrenoceptor alpha 2A
AGER advanced glycosylation end product-specific receptor
AGTR1 angiotensin II receptor, type 1
AGXT alanine-glyoxylate aminotransferase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALOX15B arachidonate 15-lipoxygenase, type B
AMELX amelogenin, X-linked
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APAF1 apoptotic peptidase activating factor 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APLP1 amyloid beta (A4) precursor-like protein 1
APOA1 apolipoprotein A-I
APOC2 apolipoprotein C-II
APOD apolipoprotein D
APP amyloid beta (A4) precursor protein
AR androgen receptor
AREG amphiregulin
ARF6 ADP-ribosylation factor 6
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARX aristaless related homeobox
ATN1 atrophin 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATXN1 ataxin 1
ATXN3 ataxin 3
ATXN7 ataxin 7
AVPR1A arginine vasopressin receptor 1A
B2M beta-2-microglobulin
BAG3 BCL2-associated athanogene 3
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCAM basal cell adhesion molecule (Lutheran blood group)
BGN biglycan
BRCA2 breast cancer 2, early onset
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1GALT1C1 C1GALT1-specific chaperone 1
CA2 carbonic anhydrase II
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMP cathelicidin antimicrobial peptide
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN1 calpain 1, (mu/I) large subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCS copper chaperone for superoxide dismutase
CD19 CD19 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD63 CD63 molecule
CD81 CD81 molecule
CD82 CD82 molecule
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK1 cyclin-dependent kinase 1
CDK5 cyclin-dependent kinase 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CDSN corneodesmosin
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CISD2 CDGSH iron sulfur domain 2
CKM creatine kinase, muscle
CLEC1B C-type lectin domain family 1, member B
CLEC2A C-type lectin domain family 2, member A
CLU clusterin
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CNOT8 CCR4-NOT transcription complex, subunit 8
COCH cochlin
COL6A1 collagen, type VI, alpha 1
CP ceruloplasmin (ferroxidase)
CPA2 carboxypeptidase A2 (pancreatic)
CRELD2 cysteine-rich with EGF-like domains 2
CRP C-reactive protein, pentraxin-related
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CRYBA1 crystallin, beta A1
CRYBB1 crystallin, beta B1
CRYBB2 crystallin, beta B2
CRYGD crystallin, gamma D
CRYGS crystallin, gamma S
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF3 colony stimulating factor 3 (granulocyte)
CSK c-src tyrosine kinase
CSNK1A1 casein kinase 1, alpha 1
CSNK1D casein kinase 1, delta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2B casein kinase 2, beta polypeptide
CSTB cystatin B (stefin B)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSK cathepsin K
CUL3 cullin 3
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYTH2 cytohesin 2
DAO D-amino-acid oxidase
DAPK3 death-associated protein kinase 3
DCN decorin
DCTN1 dynactin 1
DES desmin
DIABLO diablo, IAP-binding mitochondrial protein
DMBT1 deleted in malignant brain tumors 1
DMD dystrophin
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB1P1 DnaJ (Hsp40) homolog, subfamily B, member 1 pseudogene 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DVL2 dishevelled segment polarity protein 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EFNB1 ephrin-B1
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
EGLN3 egl-9 family hypoxia-inducible factor 3
ELN elastin
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EP300 E1A binding protein p300
EPHA4 EPH receptor A4
EPHB1 EPH receptor B1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
F10 coagulation factor X
F11 coagulation factor XI
F11R F11 receptor
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL3 coagulation factor II (thrombin) receptor-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F9 coagulation factor IX
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBN1 fibrillin 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
FKBP1A FK506 binding protein 1A, 12kDa
FN1 fibronectin 1
FOXL2 forkhead box L2
FUS FUS RNA binding protein
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GAS6 growth arrest-specific 6
GBA glucosidase, beta, acid
GCG glucagon
GFAP glial fibrillary acidic protein
GH1 growth hormone 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA1 gap junction protein, alpha 1, 43kDa
GLA galactosidase, alpha
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP6 glycoprotein VI (platelet)
GPHN gephyrin
GRB2 growth factor receptor-bound protein 2
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GYS1 glycogen synthase 1 (muscle)
HLA-A major histocompatibility complex, class I, A
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HMBS hydroxymethylbilane synthase
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB8 heat shock 22kDa protein 8
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTT huntingtin
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGK immunoglobulin kappa locus
IGKC immunoglobulin kappa constant
IL13 interleukin 13
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
ILK integrin-linked kinase
INS insulin
INSR insulin receptor
IRF1 interferon regulatory factor 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITM2B integral membrane protein 2B
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUN jun proto-oncogene
KCNIP1 Kv channel interacting protein 1
KIF2C kinesin family member 2C
KNG1 kininogen 1
LALBA lactalbumin, alpha-
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
LONP1 lon peptidase 1, mitochondrial
LY96 lymphocyte antigen 96
LYZ lysozyme
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MARK1 MAP/microtubule affinity-regulating kinase 1
MB myoglobin
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MERTK MER proto-oncogene, tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MIR16-1 microRNA 16-1
MIR17 microRNA 17
MLH1 mutL homolog 1
MLPH melanophilin
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MPZ myelin protein zero
MRRF mitochondrial ribosome recycling factor
MRVI1 murine retrovirus integration site 1 homolog
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MT2A metallothionein 2A
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYD88 myeloid differentiation primary response 88
MYH9 myosin, heavy chain 9, non-muscle
MYLK myosin light chain kinase
MYO5A myosin VA (heavy chain 12, myoxin)
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAGLU N-acetylglucosaminidase, alpha
NBR1 neighbor of BRCA1 gene 1
NCAM1 neural cell adhesion molecule 1
NCEH1 neutral cholesterol ester hydrolase 1
NEU1 sialidase 1 (lysosomal sialidase)
NEU3 sialidase 3 (membrane sialidase)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFR nerve growth factor receptor
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NOX1 NADPH oxidase 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRG1 neuregulin 1
NTM neurotrimin
NUB1 negative regulator of ubiquitin-like proteins 1
OCLN occludin
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORAI1 ORAI calcium release-activated calcium modulator 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PABPN1 poly(A) binding protein, nuclear 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PANX1 pannexin 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARVB parvin, beta
PBX1 pre-B-cell leukemia homeobox 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDIA2 protein disulfide isomerase family A, member 2
PDIA3 protein disulfide isomerase family A, member 3
PDPN podoplanin
PEAR1 platelet endothelial aggregation receptor 1
PFN1 profilin 1
PFN2 profilin 2
PHB prohibitin
PHB2 prohibitin 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PINK1 PTEN induced putative kinase 1
PLA2G10 phospholipase A2, group X
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLG plasminogen
PLSCR1 phospholipid scramblase 1
PLSCR2 phospholipid scramblase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMP22 peripheral myelin protein 22
PON1 paraoxonase 1
PPARD peroxisome proliferator-activated receptor delta
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRNP prion protein
PRPH peripherin
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PSEN1 presenilin 1
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTAFR platelet-activating factor receptor
PTEN phosphatase and tensin homolog
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PYCARD PYD and CARD domain containing
RAB27A RAB27A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
REG3A regenerating islet-derived 3 alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RNASE3 ribonuclease, RNase A family, 3
RNASE7 ribonuclease, RNase A family, 7
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RS1 retinoschisin 1
RTN3 reticulon 3
S100A6 S100 calcium binding protein A6
S1PR2 sphingosine-1-phosphate receptor 2
SCAMP5 secretory carrier membrane protein 5
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEPP1 selenoprotein P, plasma, 1
SEPT4 septin 4
SERF1A small EDRK-rich factor 1A (telomeric)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFTPC surfactant protein C
SFTPD surfactant protein D
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SNAP23 synaptosomal-associated protein, 23kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCAIP synuclein, alpha interacting protein
SNCB synuclein, beta
SOD1 superoxide dismutase 1, soluble
SOS1 son of sevenless homolog 1 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
SPTA1 spectrin, alpha, erythrocytic 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQSTM1 sequestosome 1
STAT5B signal transducer and activator of transcription 5B
STIM1 stromal interaction molecule 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO1 small ubiquitin-like modifier 1
SYK spleen tyrosine kinase
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TACR3 tachykinin receptor 3
TARDBP TAR DNA binding protein
TBXA2R thromboxane A2 receptor
TEAD4 TEA domain family member 4
TFEB transcription factor EB
TFF2 trefoil factor 2
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGM1 transglutaminase 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THPO thrombopoietin
TIMP4 TIMP metallopeptidase inhibitor 4
TJP1 tight junction protein 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNPO1 transportin 1
TNRC6A trinucleotide repeat containing 6A
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TRAF2 TNF receptor-associated factor 2
TREML1 triggering receptor expressed on myeloid cells-like 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSLP thymic stromal lymphopoietin
TTR transthyretin
UBE3A ubiquitin protein ligase E3A
UBQLN2 ubiquilin 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCN2 urocortin 2
UTRN utrophin
UXT ubiquitously-expressed, prefoldin-like chaperone
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VDAC1 voltage-dependent anion channel 1
VKORC1 vitamin K epoxide reductase complex, subunit 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VSNL1 visinin-like 1
VTN vitronectin
VWF von Willebrand factor
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WNT3A wingless-type MMTV integration site family, member 3A
XBP1 X-box binding protein 1
YARS tyrosyl-tRNA synthetase
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H14 zinc finger CCCH-type containing 14
ZMYND11 zinc finger, MYND-type containing 11