aggresome Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules. (Gene Ontology, GO_0016235)
External Link http://amigo.geneontology.org/amigo/term/GO:0016235
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Genes

27 proteins localized to the aggresome cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
CABIN1 calcineurin binding protein 1
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
DBF4B DBF4 zinc finger B
EEF2 eukaryotic translation elongation factor 2
EID1 EP300 interacting inhibitor of differentiation 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
HDAC6 histone deacetylase 6
IRF2BP1 interferon regulatory factor 2 binding protein 1
LIN28B lin-28 homolog B (C. elegans)
MECOM MDS1 and EVI1 complex locus
MVB12A multivesicular body subunit 12A
PARK2 parkin RBR E3 ubiquitin protein ligase
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
RNF32 ring finger protein 32
SEC62 SEC62 homolog (S. cerevisiae)
SFMBT2 Scm-like with four mbt domains 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLFN11 schlafen family member 11
SQSTM1 sequestosome 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TRIM37 tripartite motif containing 37
TRIM66 tripartite motif containing 66
UBD ubiquitin D
UCMA upper zone of growth plate and cartilage matrix associated
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
XRN2 5'-3' exoribonuclease 2