aggresome Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules. (Gene Ontology, GO_0016235)
External Link http://amigo.geneontology.org/amigo/term/GO:0016235
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Genes

36 proteins localized to the aggresome cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
BAG3 BCL2-associated athanogene 3
CABIN1 calcineurin binding protein 1
CARD14 caspase recruitment domain family, member 14
DVL2 dishevelled segment polarity protein 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EEF2 eukaryotic translation elongation factor 2
EPS15 epidermal growth factor receptor pathway substrate 15
FGR FGR proto-oncogene, Src family tyrosine kinase
HDAC6 histone deacetylase 6
HOXC9 homeobox C9
HOXD3 homeobox D3
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
KLF8 Kruppel-like factor 8
KLHL14 kelch-like family member 14
PARK2 parkin RBR E3 ubiquitin protein ligase
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PRDM16 PR domain containing 16
PRKCQ protein kinase C, theta
PSEN1 presenilin 1
RANGAP1 Ran GTPase activating protein 1
RNF32 ring finger protein 32
SFMBT2 Scm-like with four mbt domains 2
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SQSTM1 sequestosome 1
STRADB STE20-related kinase adaptor beta
TDP2 tyrosyl-DNA phosphodiesterase 2
TRIM37 tripartite motif containing 37
TRIM66 tripartite motif containing 66
UBD ubiquitin D
UBQLN1 ubiquilin 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
XRN2 5'-3' exoribonuclease 2
ZBTB14 zinc finger and BTB domain containing 14