aging Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700). (Gene Ontology, GO_0007568)
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Genes

81 proteins co-occuring with the biological term aging in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AKT1 v-akt murine thymoma viral oncogene homolog 1
BCAR1 breast cancer anti-estrogen resistance 1
BRCA1 breast cancer 1, early onset
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CELF1 CUGBP, Elav-like family member 1
CFL1 cofilin 1 (non-muscle)
CREB1 cAMP responsive element binding protein 1
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
EEF2 eukaryotic translation elongation factor 2
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
GRIA1 glutamate receptor, ionotropic, AMPA 1
GSK3B glycogen synthase kinase 3 beta
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H3A histone cluster 1, H3a
HSF1 heat shock transcription factor 1
HSPB1 heat shock 27kDa protein 1
INSR insulin receptor
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
LEPR leptin receptor
LIMK1 LIM domain kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPT microtubule-associated protein tau
MBP myelin basic protein
MIP major intrinsic protein of lens fiber
MME membrane metallo-endopeptidase
MPZ myelin protein zero
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBPC3 myosin binding protein C, cardiac
MYH9 myosin, heavy chain 9, non-muscle
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NBN nibrin
NKX3-1 NK3 homeobox 1
NOS3 nitric oxide synthase 3 (endothelial cell)
PDZD11 PDZ domain containing 11
PKLR pyruvate kinase, liver and RBC
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLN phospholamban
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRPF19 pre-mRNA processing factor 19
PTK2 protein tyrosine kinase 2
PTPRA protein tyrosine phosphatase, receptor type, A
PXN paxillin
RPA2 replication protein A2, 32kDa
RPH3A rabphilin 3A
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RYR2 ryanodine receptor 2 (cardiac)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT1 sirtuin 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBC1D4 TBC1 domain family, member 4
TERT telomerase reverse transcriptase
TH tyrosine hydroxylase
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TSC2 tuberous sclerosis 2
TTN titin
UBTF upstream binding transcription factor, RNA polymerase I
WRN Werner syndrome, RecQ helicase-like