agonist Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

333 genes co-occuring with the biological term agonist in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACAT2 acetyl-CoA acetyltransferase 2
ADA adenosine deaminase
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
AFP alpha-fetoprotein
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHR aryl hydrocarbon receptor
AKAP12 A kinase (PRKA) anchor protein 12
AKAP5 A kinase (PRKA) anchor protein 5
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX15 arachidonate 15-lipoxygenase
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPT4 angiopoietin 4
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARF6 ADP-ribosylation factor 6
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL2L1 BCL2-like 1
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BID BH3 interacting domain death agonist
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRS3 bombesin-like receptor 3
C5AR1 complement component 5a receptor 1
CABP1 calcium binding protein 1
CALCA calcitonin-related polypeptide alpha
CALCR calcitonin receptor
CALML5 calmodulin-like 5
CARD9 caspase recruitment domain family, member 9
CAST calpastatin
CCK cholecystokinin
CCKAR cholecystokinin A receptor
CCL1 chemokine (C-C motif) ligand 1
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCL4 chemokine (C-C motif) ligand 4
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD4 CD4 molecule
CD40LG CD40 ligand
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8A CD8a molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CGB5 chorionic gonadotropin, beta polypeptide 5
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLEC1B C-type lectin domain family 1, member B
CMKLR1 chemerin chemokine-like receptor 1
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CPB2 carboxypeptidase B2 (plasma)
CREBZF CREB/ATF bZIP transcription factor
CRHR1 corticotropin releasing hormone receptor 1
CRYAB crystallin, alpha B
CSF3 colony stimulating factor 3 (granulocyte)
CTSS cathepsin S
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DEFB103B defensin, beta 103B
DPP4 dipeptidyl-peptidase 4
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD5 dopamine receptor D5
EDN1 endothelin 1
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
ESRRG estrogen-related receptor gamma
EZR ezrin
F13A1 coagulation factor XIII, A1 polypeptide
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
FASLG Fas ligand (TNF superfamily, member 6)
FERMT3 fermitin family member 3
FFAR1 free fatty acid receptor 1
FFAR4 free fatty acid receptor 4
FGFR1 fibroblast growth factor receptor 1
FLNA filamin A, alpha
FPR1 formyl peptide receptor 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GHSR growth hormone secretagogue receptor
GLP1R glucagon-like peptide 1 receptor
GLRA1 glycine receptor, alpha 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GP6 glycoprotein VI (platelet)
GPER1 G protein-coupled estrogen receptor 1
GPR119 G protein-coupled receptor 119
GPR183 G protein-coupled receptor 183
GPR35 G protein-coupled receptor 35
GPR39 G protein-coupled receptor 39
GPRC6A G protein-coupled receptor, class C, group 6, member A
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRK4 G protein-coupled receptor kinase 4
GRK5 G protein-coupled receptor kinase 5
GRM1 glutamate receptor, metabotropic 1
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GRM8 glutamate receptor, metabotropic 8
GRP gastrin-releasing peptide
GRPR gastrin-releasing peptide receptor
HCAR1 hydroxycarboxylic acid receptor 1
HCAR2 hydroxycarboxylic acid receptor 2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HCRTR1 hypocretin (orexin) receptor 1
HCRTR2 hypocretin (orexin) receptor 2
HMOX1 heme oxygenase 1
HRH1 histamine receptor H1
HRH2 histamine receptor H2
HRH3 histamine receptor H3
HRH4 histamine receptor H4
HSPB8 heat shock 22kDa protein 8
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IFNG interferon, gamma
IL11 interleukin 11
IL11RA interleukin 11 receptor, alpha
IL12B interleukin 12B
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2RB interleukin 2 receptor, beta
IL36A interleukin 36, alpha
IL36B interleukin 36, beta
IL36G interleukin 36, gamma
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDR kinase insert domain receptor
LGALS9 lectin, galactoside-binding, soluble, 9
LOX lysyl oxidase
LPL lipoprotein lipase
LTB4R leukotriene B4 receptor
LY96 lymphocyte antigen 96
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK14 mitogen-activated protein kinase 14
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC4R melanocortin 4 receptor
MCHR1 melanin-concentrating hormone receptor 1
MCHR2 melanin-concentrating hormone receptor 2
MIRLET7F1 microRNA let-7f-1
MLNR motilin receptor
MMP12 matrix metallopeptidase 12
MOK MOK protein kinase
MPL MPL proto-oncogene, thrombopoietin receptor
MT2A metallothionein 2A
MTNR1B melatonin receptor 1B
MUC1 mucin 1, cell surface associated
NCF4 neutrophil cytosolic factor 4, 40kDa
NCOA2 nuclear receptor coactivator 2
NCOA4 nuclear receptor coactivator 4
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NLRP3 NLR family, pyrin domain containing 3
NMUR2 neuromedin U receptor 2
NOD2 nucleotide-binding oligomerization domain containing 2
NOX1 NADPH oxidase 1
NOXO1 NADPH oxidase organizer 1
NPC1 Niemann-Pick disease, type C1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRG1 neuregulin 1
NRP1 neuropilin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUPR1 nuclear protein, transcriptional regulator, 1
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
OR10G4 olfactory receptor, family 10, subfamily G, member 4
ORAI1 ORAI calcium release-activated calcium modulator 1
OXTR oxytocin receptor
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAQR3 progestin and adipoQ receptor family member III
PDE4A phosphodiesterase 4A, cAMP-specific
PDX1 pancreatic and duodenal homeobox 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G15 phospholipase A2, group XV
PLCG1 phospholipase C, gamma 1
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKD2 protein kinase D2
PRKG1 protein kinase, cGMP-dependent, type I
PTGDR2 prostaglandin D2 receptor 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTK2B protein tyrosine kinase 2 beta
RAB11A RAB11A, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAD51 RAD51 recombinase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RARG retinoic acid receptor, gamma
RGN regucalcin
RGS2 regulator of G-protein signaling 2
RHO rhodopsin
RHOA ras homolog family member A
RHOH ras homolog family member H
RORA RAR-related orphan receptor A
RPLP2 ribosomal protein, large, P2
RPS19 ribosomal protein S19
RXFP1 relaxin/insulin-like family peptide receptor 1
RXRA retinoid X receptor, alpha
S1PR1 sphingosine-1-phosphate receptor 1
SET SET nuclear proto-oncogene
SIRT1 sirtuin 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX4 SRY (sex determining region Y)-box 4
SRA1 steroid receptor RNA activator 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSTR2 somatostatin receptor 2
STS steroid sulfatase (microsomal), isozyme S
TACR2 tachykinin receptor 2
TBXA2R thromboxane A2 receptor
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
THRB thyroid hormone receptor, beta
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLN1 talin 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TNC tenascin C
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP53 tumor protein p53
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSHR thyroid stimulating hormone receptor
TWSG1 twisted gastrulation BMP signaling modulator 1
TXNIP thioredoxin interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UMOD uromodulin
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIPR2 vasoactive intestinal peptide receptor 2
VSNL1 visinin-like 1
WLS wntless Wnt ligand secretion mediator
XCR1 chemokine (C motif) receptor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase