agoraphobia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A phobic disorder involving the specific anxiety about being in a place or situation where escape is difficult or embarrassing or where help may be unavailable. (Human Disease Ontology, DOID_593)
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Genes

68 genes co-occuring with the disease agoraphobia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
USP39 ubiquitin specific peptidase 39 1.56
OPRK1 opioid receptor, kappa 1 1.52248
MAOA monoamine oxidase A 1.51589
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.30532
SPX spexin hormone 1.26081
PTK7 protein tyrosine kinase 7 (inactive) 1.18066
CCKBR cholecystokinin B receptor 1.12741
KCTD5 potassium channel tetramerization domain containing 5 1.12361
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.09797
RGS7 regulator of G-protein signaling 7 0.974221
ADORA2A adenosine A2a receptor 0.964567
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.957033
RGS2 regulator of G-protein signaling 2 0.953273
NPY5R neuropeptide Y receptor Y5 0.925039
MAP2K5 mitogen-activated protein kinase kinase 5 0.904854
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 0.849126
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.793771
AMY1C amylase, alpha 1C (salivary) 0.782707
AMY1A amylase, alpha 1A (salivary) 0.782707
AMY1B amylase, alpha 1B (salivary) 0.782707
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.754527
ORM1 orosomucoid 1 0.737865
NPY1R neuropeptide Y receptor Y1 0.728952
TPH2 tryptophan hydroxylase 2 0.727738
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.725716
COMT catechol-O-methyltransferase 0.715618
CTNND2 catenin (cadherin-associated protein), delta 2 0.698313
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.683892
NBPF8 neuroblastoma breakpoint family, member 8 0.679898
TRDN triadin 0.676308
DCXR dicarbonyl/L-xylulose reductase 0.656046
ADAM28 ADAM metallopeptidase domain 28 0.654858
SIM2 single-minded family bHLH transcription factor 2 0.649718
NPSR1 neuropeptide S receptor 1 0.626103
SLC45A2 solute carrier family 45, member 2 0.610838
RORA RAR-related orphan receptor A 0.606543
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.58433
ASIC1 acid sensing (proton gated) ion channel 1 0.529222
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.523045
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.497703
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.487407
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.476772
MEGF6 multiple EGF-like-domains 6 0.474498
POLI polymerase (DNA directed) iota 0.442795
GRPR gastrin-releasing peptide receptor 0.426265
NCR3 natural cytotoxicity triggering receptor 3 0.414276
BDNF brain-derived neurotrophic factor 0.406425
CARS cysteinyl-tRNA synthetase 0.399334
GLO1 glyoxalase I 0.376661
NBPF10 neuroblastoma breakpoint family, member 10 0.364824
POMC proopiomelanocortin 0.344207
BPI bactericidal/permeability-increasing protein 0.342006
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.329565
ADRA1D adrenoceptor alpha 1D 0.3292
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.328105
DRD4 dopamine receptor D4 0.316819
CRH corticotropin releasing hormone 0.315729
CCK cholecystokinin 0.311739
NPY neuropeptide Y 0.308118
CREM cAMP responsive element modulator 0.303059
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.295492
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.292257
ADA adenosine deaminase 0.291898
MCM8 minichromosome maintenance complex component 8 0.26266
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.252422
TPH1 tryptophan hydroxylase 1 0.248905
FGD1 FYVE, RhoGEF and PH domain containing 1 0.204593
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.193915