ajmaline-1749 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ajmaline-1749 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA1 adenosine A1 receptor
ADRA2B adrenoceptor alpha 2B
AGRN agrin
AIM1L absent in melanoma 1-like
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALX3 ALX homeobox 3
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BIRC7 baculoviral IAP repeat containing 7
BMP2K BMP2 inducible kinase
C22ORF31 chromosome 22 open reading frame 31
C2ORF54 chromosome 2 open reading frame 54
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACFD1 calcium channel flower domain containing 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CCS copper chaperone for superoxide dismutase
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CENPO centromere protein O
CHN2 chimerin 2
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNTFR ciliary neurotrophic factor receptor
COMT catechol-O-methyltransferase
CPTP ceramide-1-phosphate transfer protein
CRTC1 CREB regulated transcription coactivator 1
CRYM crystallin, mu
DGCR8 DGCR8 microprocessor complex subunit
DIO2 deiodinase, iodothyronine, type II
DNAH7 dynein, axonemal, heavy chain 7
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP26 dual specificity phosphatase 26 (putative)
EFNB3 ephrin-B3
EFR3B EFR3 homolog B (S. cerevisiae)
ELN elastin
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGFR1 fibroblast growth factor receptor 1
FMNL1 formin-like 1
GADD45B growth arrest and DNA-damage-inducible, beta
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNL1 guanine nucleotide binding protein-like 1
GPX3 glutathione peroxidase 3
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAND1 heart and neural crest derivatives expressed 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIF25 kinesin family member 25
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRT17 keratin 17, type I
LAMA2 laminin, alpha 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMS2 LIM and senescent cell antigen-like domains 2
LINC00312 long intergenic non-protein coding RNA 312
LLGL2 lethal giant larvae homolog 2 (Drosophila)
MED27 mediator complex subunit 27
METTL7A methyltransferase like 7A
MMP25 matrix metallopeptidase 25
MOB3B MOB kinase activator 3B
MRC2 mannose receptor, C type 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MXRA8 matrix-remodelling associated 8
MYF6 myogenic factor 6 (herculin)
NUP214 nucleoporin 214kDa
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PADI1 peptidyl arginine deiminase, type I
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAQR6 progestin and adipoQ receptor family member VI
PBX2 pre-B-cell leukemia homeobox 2
PELP1 proline, glutamate and leucine rich protein 1
PHF3 PHD finger protein 3
PKD2L1 polycystic kidney disease 2-like 1
PLCG1 phospholipase C, gamma 1
PLK3 polo-like kinase 3
POLH polymerase (DNA directed), eta
PPARA peroxisome proliferator-activated receptor alpha
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PRODH2 proline dehydrogenase (oxidase) 2
PSEN2 presenilin 2
PTGES prostaglandin E synthase
PTN pleiotrophin
RAB40B RAB40B, member RAS oncogene family
RNF39 ring finger protein 39
RXRA retinoid X receptor, alpha
SAMD14 sterile alpha motif domain containing 14
SCN5A sodium channel, voltage gated, type V alpha subunit
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPDEF SAM pointed domain containing ETS transcription factor
SPTB spectrin, beta, erythrocytic
TMCC2 transmembrane and coiled-coil domain family 2
TMSB4Y thymosin beta 4, Y-linked
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WIZ widely interspaced zinc finger motifs

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AIM2 absent in melanoma 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARL4A ADP-ribosylation factor-like 4A
ARRB2 arrestin, beta 2
ASTE1 asteroid homolog 1 (Drosophila)
AVEN apoptosis, caspase activation inhibitor
AZU1 azurocidin 1
BST1 bone marrow stromal cell antigen 1
BYSL bystin-like
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL20 chemokine (C-C motif) ligand 20
CD9 CD9 molecule
CDC45 cell division cycle 45
CDCA8 cell division cycle associated 8
CFAP20 cilia and flagella associated protein 20
CFL1 cofilin 1 (non-muscle)
CLCN6 chloride channel, voltage-sensitive 6
CLEC16A C-type lectin domain family 16, member A
COMMD9 COMM domain containing 9
CORO7 coronin 7
DBF4B DBF4 zinc finger B
DPF2 D4, zinc and double PHD fingers family 2
DPP3 dipeptidyl-peptidase 3
EMC9 ER membrane protein complex subunit 9
EXOC3 exocyst complex component 3
FBXW4 F-box and WD repeat domain containing 4
FZD2 frizzled class receptor 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDE1 glycerophosphodiester phosphodiesterase 1
GLOD4 glyoxalase domain containing 4
GOLGA3 golgin A3
GPS2 G protein pathway suppressor 2
H1FX H1 histone family, member X
IPO4 importin 4
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
KEAP1 kelch-like ECH-associated protein 1
KIZ kizuna centrosomal protein
LGALS9 lectin, galactoside-binding, soluble, 9
LRRK1 leucine-rich repeat kinase 1
MAGOHB mago-nashi homolog B (Drosophila)
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MRPS34 mitochondrial ribosomal protein S34
MTG1 mitochondrial ribosome-associated GTPase 1
MYO9A myosin IXA
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NADSYN1 NAD synthetase 1
NAGK N-acetylglucosamine kinase
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFE2 nuclear factor, erythroid 2
NLRX1 NLR family member X1
NOP14 NOP14 nucleolar protein
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NVL nuclear VCP-like
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
ORC1 origin recognition complex, subunit 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAK1IP1 PAK1 interacting protein 1
PCTP phosphatidylcholine transfer protein
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLK1 polo-like kinase 1
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
PPP4C protein phosphatase 4, catalytic subunit
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB4B RAB4B, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM10 RNA binding motif protein 10
RBM14 RNA binding motif protein 14
RNF123 ring finger protein 123
RNF167 ring finger protein 167
S100PBP S100P binding protein
SAC3D1 SAC3 domain containing 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNX6 sorting nexin 6
STRA13 stimulated by retinoic acid 13
STX4 syntaxin 4
STYXL1 serine/threonine/tyrosine interacting-like 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM106C transmembrane protein 106C
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TTC31 tetratricopeptide repeat domain 31
TUFM Tu translation elongation factor, mitochondrial
UROS uroporphyrinogen III synthase
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
WDR6 WD repeat domain 6
YIPF1 Yip1 domain family, member 1
ZBTB48 zinc finger and BTB domain containing 48
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC24 zinc finger, DHHC-type containing 24