ajmaline-7484 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ajmaline-7484 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFAP1 actin filament associated protein 1
AIM2 absent in melanoma 2
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
AQP3 aquaporin 3 (Gill blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID1A AT rich interactive domain 1A (SWI-like)
ATP10A ATPase, class V, type 10A
BEGAIN brain-enriched guanylate kinase-associated
BMP2K BMP2 inducible kinase
C10ORF76 chromosome 10 open reading frame 76
C11ORF80 chromosome 11 open reading frame 80
CADM4 cell adhesion molecule 4
CD83 CD83 molecule
CDON cell adhesion associated, oncogene regulated
CLCN7 chloride channel, voltage-sensitive 7
CLTA clathrin, light chain A
CPA4 carboxypeptidase A4
CXCR4 chemokine (C-X-C motif) receptor 4
DLX4 distal-less homeobox 4
DMC1 DNA meiotic recombinase 1
DSCAM Down syndrome cell adhesion molecule
DST dystonin
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FAM204A family with sequence similarity 204, member A
FLOT1 flotillin 1
GAR1 GAR1 ribonucleoprotein
GID4 GID complex subunit 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR153 G protein-coupled receptor 153
GSK3A glycogen synthase kinase 3 alpha
HAND1 heart and neural crest derivatives expressed 1
HEXA hexosaminidase A (alpha polypeptide)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXB5 homeobox B5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGFBP3 insulin-like growth factor binding protein 3
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JUN jun proto-oncogene
KITLG KIT ligand
KMT2A lysine (K)-specific methyltransferase 2A
LAMB1 laminin, beta 1
LAMP1 lysosomal-associated membrane protein 1
LRP2 low density lipoprotein receptor-related protein 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP9 microtubule-associated protein 9
MCF2L MCF.2 cell line derived transforming sequence-like
MDM4 MDM4, p53 regulator
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
NDE1 nudE neurodevelopment protein 1
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMT1 N-myristoyltransferase 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PARD6B par-6 family cell polarity regulator beta
PCDHGA8 protocadherin gamma subfamily A, 8
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PRODH proline dehydrogenase (oxidase) 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTRF polymerase I and transcript release factor
QKI QKI, KH domain containing, RNA binding
RHEB Ras homolog enriched in brain
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RSL1D1 ribosomal L1 domain containing 1
RXRB retinoid X receptor, beta
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIRT3 sirtuin 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SP100 SP100 nuclear antigen
SP140L SP140 nuclear body protein-like
SPN sialophorin
SUGP1 SURP and G patch domain containing 1
SYNJ2 synaptojanin 2
TAOK2 TAO kinase 2
TAPBP TAP binding protein (tapasin)
TDRD1 tudor domain containing 1
THBS3 thrombospondin 3
TMC6 transmembrane channel-like 6
TMEM242 transmembrane protein 242
TNS2 tensin 2
VAMP5 vesicle-associated membrane protein 5
VEGFB vascular endothelial growth factor B
VIPR1 vasoactive intestinal peptide receptor 1
ZBED1 zinc finger, BED-type containing 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF211 zinc finger protein 211
ZNF280D zinc finger protein 280D
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF767P zinc finger family member 767, pseudogene

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACSS3 acyl-CoA synthetase short-chain family member 3
ADCY6 adenylate cyclase 6
ADGRE5 adhesion G protein-coupled receptor E5
AMT aminomethyltransferase
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA1 annexin A1
APLP1 amyloid beta (A4) precursor-like protein 1
ARMC6 armadillo repeat containing 6
BBC3 BCL2 binding component 3
C22ORF29 chromosome 22 open reading frame 29
C2ORF27A chromosome 2 open reading frame 27A
C2ORF44 chromosome 2 open reading frame 44
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP85 centrosomal protein 85kDa
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CPTP ceramide-1-phosphate transfer protein
CRELD1 cysteine-rich with EGF-like domains 1
CTC1 CTS telomere maintenance complex component 1
CTNNBIP1 catenin, beta interacting protein 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGKD diacylglycerol kinase, delta 130kDa
DOCK1 dedicator of cytokinesis 1
DVL1 dishevelled segment polarity protein 1
DYSF dysferlin
ELOVL4 ELOVL fatty acid elongase 4
ERO1L ERO1-like (S. cerevisiae)
FAM184A family with sequence similarity 184, member A
FANCC Fanconi anemia, complementation group C
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FGGY FGGY carbohydrate kinase domain containing
GAB2 GRB2-associated binding protein 2
GCHFR GTP cyclohydrolase I feedback regulator
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR19 G protein-coupled receptor 19
HDAC4 histone deacetylase 4
HIST1H3B histone cluster 1, H3b
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXC10 homeobox C10
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
KDM7A lysine (K)-specific demethylase 7A
KLF11 Kruppel-like factor 11
KLHL36 kelch-like family member 36
LGALS4 lectin, galactoside-binding, soluble, 4
LIG4 ligase IV, DNA, ATP-dependent
LIMS2 LIM and senescent cell antigen-like domains 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MUC3A mucin 3A, cell surface associated
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PARP12 poly (ADP-ribose) polymerase family, member 12
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PTCD1 pentatricopeptide repeat domain 1
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RNF123 ring finger protein 123
RNF219 ring finger protein 219
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCHIP1 schwannomin interacting protein 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STBD1 starch binding domain 1
STK25 serine/threonine kinase 25
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TKFC triokinase/FMN cyclase
TMPRSS4 transmembrane protease, serine 4
TPCN1 two pore segment channel 1
TRAF2 TNF receptor-associated factor 2
TRAPPC6A trafficking protein particle complex 6A
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UBIAD1 UbiA prenyltransferase domain containing 1
UBXN6 UBX domain protein 6
ULBP2 UL16 binding protein 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
WDR4 WD repeat domain 4
XYLT2 xylosyltransferase II
ZC3H12A zinc finger CCCH-type containing 12A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMAT5 zinc finger, matrin-type 5
ZNF134 zinc finger protein 134
ZNF668 zinc finger protein 668
ZSCAN26 zinc finger and SCAN domain containing 26