akt Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

383 proteins co-occuring with the biological term akt in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACIN1 apoptotic chromatin condensation inducer 1
ACLY ATP citrate lyase
ADAM17 ADAM metallopeptidase domain 17
ADRB2 adrenoceptor beta 2, surface
AFAP1L2 actin filament associated protein 1-like 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALYREF Aly/REF export factor
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGAP22 Rho GTPase activating protein 22
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATXN1 ataxin 1
AVPR2 arginine vasopressin receptor 2
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BEX1 brain expressed, X-linked 1
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMX BMX non-receptor tyrosine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
CA9 carbonic anhydrase IX
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBY1 chibby homolog 1 (Drosophila)
CC2D1A coiled-coil and C2 domain containing 1A
CCDC88A coiled-coil domain containing 88A
CCKBR cholecystokinin B receptor
CCND1 cyclin D1
CD19 CD19 molecule
CD5 CD5 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC25B cell division cycle 25B
CDC37 cell division cycle 37
CDCA7 cell division cycle associated 7
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CELF1 CUGBP, Elav-like family member 1
CEP250 centrosomal protein 250kDa
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLK2 CDC-like kinase 2
COPS6 COP9 signalosome subunit 6
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRTC2 CREB regulated transcription coactivator 2
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSNK1D casein kinase 1, delta
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYTH3 cytohesin 3
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DDR1 discoidin domain receptor tyrosine kinase 1
DEPTOR DEP domain containing MTOR-interacting protein
DLC1 DLC1 Rho GTPase activating protein
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DOCK6 dedicator of cytokinesis 6
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPYSL2 dihydropyrimidinase-like 2
EDC3 enhancer of mRNA decapping 3
EEF2 eukaryotic translation elongation factor 2
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXOC4 exocyst complex component 4
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
FAM129A family with sequence similarity 129, member A
FANCA Fanconi anemia, complementation group A
FBXW8 F-box and WD repeat domain containing 8
FHIT fragile histidine triad
FLII flightless I homolog (Drosophila)
FLNC filamin C, gamma
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FOXA2 forkhead box A2
FOXG1 forkhead box G1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
G6PD glucose-6-phosphate dehydrogenase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAP43 growth associated protein 43
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GJA1 gap junction protein, alpha 1, 43kDa
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GOLGA3 golgin A3
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GRB10 growth factor receptor-bound protein 10
GRB7 growth factor receptor-bound protein 7
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
H3F3B H3 histone, family 3B (H3.3B)
HDAC6 histone deacetylase 6
HIST1H2BB histone cluster 1, H2bb
HIST1H3A histone cluster 1, H3a
HJURP Holliday junction recognition protein
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB1 heat shock 27kDa protein 1
HTRA2 HtrA serine peptidase 2
HTT huntingtin
IFI16 interferon, gamma-inducible protein 16
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL21R interleukin 21 receptor
IL2RB interleukin 2 receptor, beta
ILF3 interleukin enhancer binding factor 3, 90kDa
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPPL1 inositol polyphosphate phosphatase-like 1
INSR insulin receptor
IP6K2 inositol hexakisphosphate kinase 2
IRAK1 interleukin-1 receptor-associated kinase 1
IRF3 interferon regulatory factor 3
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KAT6A K(lysine) acetyltransferase 6A
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDR kinase insert domain receptor
KHSRP KH-type splicing regulatory protein
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAT linker for activation of T cells
LEPR leptin receptor
LIPE lipase, hormone-sensitive
LMNA lamin A/C
LPXN leupaxin
LRP6 low density lipoprotein receptor-related protein 6
LTB4R2 leukotriene B4 receptor 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MME membrane metallo-endopeptidase
MPL MPL proto-oncogene, thrombopoietin receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MXD1 MAX dimerization protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYO5A myosin VA (heavy chain 12, myoxin)
NCF1 neutrophil cytosolic factor 1
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NDFIP2 Nedd4 family interacting protein 2
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF2 neurofibromin 2 (merlin)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUAK1 NUAK family, SNF1-like kinase, 1
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OSBPL9 oxysterol binding protein-like 9
PA2G4 proliferation-associated 2G4, 38kDa
PACS2 phosphofurin acidic cluster sorting protein 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALLD palladin, cytoskeletal associated protein
PAWR PRKC, apoptosis, WT1, regulator
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PEA15 phosphoprotein enriched in astrocytes 15
PELP1 proline, glutamate and leucine rich protein 1
PGRMC1 progesterone receptor membrane component 1
PHB prohibitin
PHB2 prohibitin 2
PHF20 PHD finger protein 20
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PKM pyruvate kinase, muscle
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PLN phospholamban
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF19 pre-mRNA processing factor 19
PRPH peripherin
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RANBP3 RAN binding protein 3
RAP1B RAP1B, member of RAS oncogene family
RARA retinoic acid receptor, alpha
RARG retinoic acid receptor, gamma
RB1 retinoblastoma 1
RBL2 retinoblastoma-like 2
RBM5 RNA binding motif protein 5
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RGCC regulator of cell cycle
RICTOR RPTOR independent companion of MTOR, complex 2
RNF11 ring finger protein 11
RPS3 ribosomal protein S3
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPTOR regulatory associated protein of MTOR, complex 1
RUNX2 runt-related transcription factor 2
S1PR1 sphingosine-1-phosphate receptor 1
SFN stratifin
SGK1 serum/glucocorticoid regulated kinase 1
SH2B2 SH2B adaptor protein 2
SH3BP4 SH3-domain binding protein 4
SH3RF1 SH3 domain containing ring finger 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SIK2 salt-inducible kinase 2
SKI SKI proto-oncogene
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SOX2 SRY (sex determining region Y)-box 2
SP1 Sp1 transcription factor
SPI1 Spi-1 proto-oncogene
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPK1 SRSF protein kinase 1
SRPK2 SRSF protein kinase 2
SRSF1 serine/arginine-rich splicing factor 1
SRSF5 serine/arginine-rich splicing factor 5
SSB Sjogren syndrome antigen B (autoantigen La)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STK11 serine/threonine kinase 11
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STK38L serine/threonine kinase 38 like
STK4 serine/threonine kinase 4
STXBP4 syntaxin binding protein 4
STYK1 serine/threonine/tyrosine kinase 1
SYK spleen tyrosine kinase
SYTL1 synaptotagmin-like 1
TAL1 T-cell acute lymphocytic leukemia 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D4 TBC1 domain family, member 4
TCF3 transcription factor 3
TEK TEK tyrosine kinase, endothelial
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERT telomerase reverse transcriptase
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
THOC5 THO complex 5
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TJP2 tight junction protein 2
TNK2 tyrosine kinase, non-receptor, 2
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP53RK TP53 regulating kinase
TSC2 tuberous sclerosis 2
TTC3 tetratricopeptide repeat domain 3
ULK1 unc-51 like autophagy activating kinase 1
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
VASP vasodilator-stimulated phosphoprotein
VCP valosin containing protein
VIM vimentin
WEE1 WEE1 G2 checkpoint kinase
WNK1 WNK lysine deficient protein kinase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZYX zyxin