akt2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description v-akt murine thymoma viral oncogene homolog 2|This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 208)
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Genes

64 genes co-occuring with the biological term akt2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
CCNA1 cyclin A1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CREB1 cAMP responsive element binding protein 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DLX5 distal-less homeobox 5
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GLI1 GLI family zinc finger 1
GRM1 glutamate receptor, metabotropic 1
GSK3B glycogen synthase kinase 3 beta
GYS1 glycogen synthase 1 (muscle)
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
KRT18 keratin 18, type I
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MIR184 microRNA 184
MIR203A microRNA 203a
MIR302B microRNA 302b
MIR708 microRNA 708
MIRLET7B microRNA let-7b
MIRLET7G microRNA let-7g
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCBP1 poly(rC) binding protein 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKCD protein kinase C, delta
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RHOBTB2 Rho-related BTB domain containing 2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS7 ribosomal protein S7
SFRP5 secreted frizzled-related protein 5
SH3RF1 SH3 domain containing ring finger 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNAI1 snail family zinc finger 1
SPHK1 sphingosine kinase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFBR1 transforming growth factor, beta receptor 1
TNF tumor necrosis factor
TWIST1 twist family bHLH transcription factor 1
VIM vimentin