alagille syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A liver disease that is characterized by an accumulation of bile in the liver resulting from a reducted number of liver small bile ducts. (Human Disease Ontology, DOID_9245)
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Genes

65 genes co-occuring with the disease alagille syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
JAG1 jagged 1 3.32356
NOTCH2 notch 2 2.21644
NOTCH2NL notch 2 N-terminal like 2.21271
NOTCH1 notch 1 1.9178
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.31319
ZNF708 zinc finger protein 708 1.17378
ZNF138 zinc finger protein 138 1.17378
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.16992
ZBTB35 zinc finger and BTB domain containing 35 1.16649
DLL3 delta-like 3 (Drosophila) 1.16435
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 1.15581
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 1.12909
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.11772
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.05093
GNLY granulysin 1.04546
ZNF132 zinc finger protein 132 1.0362
PAX1 paired box 1 1.02819
ZNF133 zinc finger protein 133 1.01343
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 0.851173
ZNF143 zinc finger protein 143 0.833558
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.823308
PLCB4 phospholipase C, beta 4 0.815514
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.793771
BAAT bile acid CoA:amino acid N-acyltransferase 0.777795
POFUT1 protein O-fucosyltransferase 1 0.767167
NOTCH3 notch 3 0.743141
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.730976
NOTCH4 notch 4 0.711989
ZNF148 zinc finger protein 148 0.679898
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.638282
BMP2 bone morphogenetic protein 2 0.626103
LCAT lecithin-cholesterol acyltransferase 0.53928
DLL1 delta-like 1 (Drosophila) 0.502675
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.501527
PPAN peter pan homolog (Drosophila) 0.480566
ANPEP alanyl (membrane) aminopeptidase 0.465038
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.451454
MIR214 microRNA 214 0.429642
ADAM17 ADAM metallopeptidase domain 17 0.410909
TJP2 tight junction protein 2 0.399707
SIX2 SIX homeobox 2 0.390397
SEMG1 semenogelin I 0.379256
CHGB chromogranin B 0.361502
MKKS McKusick-Kaufman syndrome 0.343473
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.337608
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.336876
DDR1 discoidin domain receptor tyrosine kinase 1 0.335778
APOC3 apolipoprotein C-III 0.332487
PTER phosphotriesterase related 0.313552
NEUROG3 neurogenin 3 0.303781
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.297291
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.287952
DLL4 delta-like 4 (Drosophila) 0.283297
SPINK5 serine peptidase inhibitor, Kazal type 5 0.272597
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.272597
JAG2 jagged 2 0.263368
HMOX2 heme oxygenase 2 0.259477
TBX1 T-box 1 0.241895
MME membrane metallo-endopeptidase 0.235268
KRT19 keratin 19, type I 0.224884
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.218034
WNT1 wingless-type MMTV integration site family, member 1 0.205916
CANX calnexin 0.194865
HMGA1 high mobility group AT-hook 1 0.192031
CHIT1 chitinase 1 (chitotriosidase) 0.161523