alclometasone-2532 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the alclometasone-2532 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACSL1 acyl-CoA synthetase long-chain family member 1
ADORA3 adenosine A3 receptor
AGFG2 ArfGAP with FG repeats 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AREG amphiregulin
ARHGAP35 Rho GTPase activating protein 35
ATP9B ATPase, class II, type 9B
BIN1 bridging integrator 1
C16ORF45 chromosome 16 open reading frame 45
CAV2 caveolin 2
CCL20 chemokine (C-C motif) ligand 20
CCSER2 coiled-coil serine-rich protein 2
CD163 CD163 molecule
CLCN4 chloride channel, voltage-sensitive 4
DENND2A DENN/MADD domain containing 2A
DIAPH2 diaphanous-related formin 2
DLC1 DLC1 Rho GTPase activating protein
DMTN dematin actin binding protein
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHA4 EPH receptor A4
FAS Fas cell surface death receptor
FHL1 four and a half LIM domains 1
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
FUS FUS RNA binding protein
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOSR2 golgi SNAP receptor complex member 2
GRPR gastrin-releasing peptide receptor
HAB1 B1 for mucin
HIST1H2AM histone cluster 1, H2am
IDS iduronate 2-sulfatase
IGFBP5 insulin-like growth factor binding protein 5
IL1R2 interleukin 1 receptor, type II
IL27RA interleukin 27 receptor, alpha
ING4 inhibitor of growth family, member 4
KIAA1109 KIAA1109
KLF9 Kruppel-like factor 9
MANSC1 MANSC domain containing 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MARC1 mitochondrial amidoxime reducing component 1
METTL7A methyltransferase like 7A
MMP13 matrix metallopeptidase 13
MTSS1 metastasis suppressor 1
MX1 MX dynamin-like GTPase 1
NBEA neurobeachin
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OLAH oleoyl-ACP hydrolase
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PER1 period circadian clock 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLSCR3 phospholipid scramblase 3
PLXNC1 plexin C1
PRKCZ protein kinase C, zeta
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTCH1 patched 1
PYY2 peptide YY, 2 (pseudogene)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RHOB ras homolog family member B
RHOH ras homolog family member H
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SDC2 syndecan 2
SENP7 SUMO1/sentrin specific peptidase 7
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPB surfactant protein B
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT5 sirtuin 5
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SOCS1 suppressor of cytokine signaling 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STARD13 StAR-related lipid transfer (START) domain containing 13
TBC1D16 TBC1 domain family, member 16
TBC1D2 TBC1 domain family, member 2
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THBS1 thrombospondin 1
TMEM39A transmembrane protein 39A
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPST1 tyrosylprotein sulfotransferase 1
TRD T cell receptor delta locus
TSC22D3 TSC22 domain family, member 3
TYMP thymidine phosphorylase
UPP1 uridine phosphorylase 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
ZBTB16 zinc finger and BTB domain containing 16
ZBTB20 zinc finger and BTB domain containing 20
ZNF442 zinc finger protein 442

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAT1 alpha tubulin acetyltransferase 1
ATG10 autophagy related 10
BTBD18 BTB (POZ) domain containing 18
C16ORF59 chromosome 16 open reading frame 59
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC92 coiled-coil domain containing 92
CCL2 chemokine (C-C motif) ligand 2
CHML choroideremia-like (Rab escort protein 2)
CLCF1 cardiotrophin-like cytokine factor 1
CLEC2D C-type lectin domain family 2, member D
COQ6 coenzyme Q6 monooxygenase
CROT carnitine O-octanoyltransferase
CTC1 CTS telomere maintenance complex component 1
CTRL chymotrypsin-like
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDAR ectodysplasin A receptor
FGGY FGGY carbohydrate kinase domain containing
FUZ fuzzy planar cell polarity protein
GAA glucosidase, alpha; acid
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCH1 GTP cyclohydrolase 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRAMD1B GRAM domain containing 1B
HAMP hepcidin antimicrobial peptide
HHLA3 HERV-H LTR-associating 3
HIST1H2AI histone cluster 1, H2ai
HIST1H2BN histone cluster 1, H2bn
IFT81 intraflagellar transport 81
IGFALS insulin-like growth factor binding protein, acid labile subunit
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAT2A K(lysine) acetyltransferase 2A
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0753 KIAA0753
KLF1 Kruppel-like factor 1 (erythroid)
KRT81 keratin 81, type II
LATS1 large tumor suppressor kinase 1
LIME1 Lck interacting transmembrane adaptor 1
LNPEP leucyl/cystinyl aminopeptidase
LTBP3 latent transforming growth factor beta binding protein 3
MAGEF1 melanoma antigen family F1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MPZ myelin protein zero
MRAS muscle RAS oncogene homolog
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYBPH myosin binding protein H
MYO1E myosin IE
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NEUROD4 neuronal differentiation 4
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PGP phosphoglycolate phosphatase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP prolactin-induced protein
PIPOX pipecolic acid oxidase
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G15 phospholipase A2, group XV
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POM121L2 POM121 transmembrane nucleoporin-like 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PRMT7 protein arginine methyltransferase 7
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAB23 RAB23, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REEP4 receptor accessory protein 4
RNF122 ring finger protein 122
RNF39 ring finger protein 39
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIL1 SIL1 nucleotide exchange factor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNX15 sorting nexin 15
SOX12 SRY (sex determining region Y)-box 12
SYNJ2BP synaptojanin 2 binding protein
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAS2R10 taste receptor, type 2, member 10
TEC tec protein tyrosine kinase
TRMT61A tRNA methyltransferase 61A
TWSG1 twisted gastrulation BMP signaling modulator 1
TXLNG taxilin gamma
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
VEGFC vascular endothelial growth factor C
ZC3H12A zinc finger CCCH-type containing 12A
ZNF480 zinc finger protein 480