alcuronium chloride-4409 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the alcuronium chloride-4409 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHSP alpha hemoglobin stabilizing protein
AIM2 absent in melanoma 2
AJAP1 adherens junctions associated protein 1
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOE apolipoprotein E
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASCL1 achaete-scute family bHLH transcription factor 1
BAIAP3 BAI1-associated protein 3
BCL6 B-cell CLL/lymphoma 6
BLZF1 basic leucine zipper nuclear factor 1
C17ORF59 chromosome 17 open reading frame 59
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDK14 cyclin-dependent kinase 14
CDK19 cyclin-dependent kinase 19
CDRT1 CMT1A duplicated region transcript 1
CHRND cholinergic receptor, nicotinic, delta (muscle)
CLTB clathrin, light chain B
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CSF1 colony stimulating factor 1 (macrophage)
CTNS cystinosin, lysosomal cystine transporter
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DEPDC5 DEP domain containing 5
DOCK9 dedicator of cytokinesis 9
ERO1LB ERO1-like beta (S. cerevisiae)
ETV5 ets variant 5
EXOSC2 exosome component 2
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGFBP1 fibroblast growth factor binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GM2A GM2 ganglioside activator
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HFE hemochromatosis
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IGF1R insulin-like growth factor 1 receptor
IGKV3-20 immunoglobulin kappa variable 3-20
IL24 interleukin 24
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KDM5B lysine (K)-specific demethylase 5B
KIAA1109 KIAA1109
LAMC2 laminin, gamma 2
LMAN1 lectin, mannose-binding, 1
LOC440895 two pore channel 3 pseudogene
LOC79999 uncharacterized LOC79999
MED25 mediator complex subunit 25
MFSD7 major facilitator superfamily domain containing 7
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRC2 mannose receptor, C type 2
MUC3B mucin 3B, cell surface associated
NID1 nidogen 1
NPY neuropeptide Y
OLFM1 olfactomedin 1
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PAX5 paired box 5
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PML promyelocytic leukemia
POU3F4 POU class 3 homeobox 4
PRDM1 PR domain containing 1, with ZNF domain
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTH2R parathyroid hormone 2 receptor
RARA retinoic acid receptor, alpha
RFPL1S RFPL1 antisense RNA 1
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPS2 ribosomal protein S2
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3GL3 SH3-domain GRB2-like 3
SHANK1 SH3 and multiple ankyrin repeat domains 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC39A9 solute carrier family 39, member 9
SLC48A1 solute carrier family 48 (heme transporter), member 1
SOCS7 suppressor of cytokine signaling 7
SPTBN2 spectrin, beta, non-erythrocytic 2
SRSF7 serine/arginine-rich splicing factor 7
STOML1 stomatin (EPB72)-like 1
SULT4A1 sulfotransferase family 4A, member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
T T, brachyury homolog (mouse)
TBXA2R thromboxane A2 receptor
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEX14 testis expressed 14
TGM2 transglutaminase 2
THAP9 THAP domain containing 9
TM4SF5 transmembrane 4 L six family member 5
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNNT2 troponin T type 2 (cardiac)
TRIM38 tripartite motif containing 38
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VCAN versican
VWA5A von Willebrand factor A domain containing 5A
XYLB xylulokinase homolog (H. influenzae)
ZBED4 zinc finger, BED-type containing 4
ZBTB18 zinc finger and BTB domain containing 18
ZC2HC1C zinc finger, C2HC-type containing 1C
ZMAT4 zinc finger, matrin-type 4

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADM adrenomedullin
AEN apoptosis enhancing nuclease
AOC2 amine oxidase, copper containing 2 (retina-specific)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAG4 BCL2-associated athanogene 4
BHLHE41 basic helix-loop-helix family, member e41
BPGM 2,3-bisphosphoglycerate mutase
C16ORF45 chromosome 16 open reading frame 45
C1ORF54 chromosome 1 open reading frame 54
CASZ1 castor zinc finger 1
CCDC9 coiled-coil domain containing 9
CDHR2 cadherin-related family member 2
CFAP45 cilia and flagella associated protein 45
CIC capicua transcriptional repressor
COPZ2 coatomer protein complex, subunit zeta 2
CORT cortistatin
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGKQ diacylglycerol kinase, theta 110kDa
DIXDC1 DIX domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DTX2 deltex 2, E3 ubiquitin ligase
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO2 F-box protein 2
FBXO31 F-box protein 31
FBXO46 F-box protein 46
FOXI1 forkhead box I1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GMEB1 glucocorticoid modulatory element binding protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR3 G protein-coupled receptor 3
GSTM2 glutathione S-transferase mu 2 (muscle)
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXB2 homeobox B2
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HYAL3 hyaluronoglucosaminidase 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
JMJD4 jumonji domain containing 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF7 Kruppel-like factor 7 (ubiquitous)
KPNA5 karyopherin alpha 5 (importin alpha 6)
KREMEN2 kringle containing transmembrane protein 2
LGALS4 lectin, galactoside-binding, soluble, 4
LMNB1 lamin B1
LOC100287590 uncharacterized LOC100287590
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP9 microtubule-associated protein 9
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
MUC3A mucin 3A, cell surface associated
NDE1 nudE neurodevelopment protein 1
NEUROD1 neuronal differentiation 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PCDHB13 protocadherin beta 13
PCDHB3 protocadherin beta 3
PDE8B phosphodiesterase 8B
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLM polymerase (DNA directed), mu
POMT2 protein-O-mannosyltransferase 2
RNF126P1 ring finger protein 126 pseudogene 1
RORC RAR-related orphan receptor C
RPL23AP32 ribosomal protein L23a pseudogene 32
SAV1 salvador family WW domain containing protein 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SMIM14 small integral membrane protein 14
SNTA1 syntrophin, alpha 1
SPRR2B small proline-rich protein 2B
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
TAS2R10 taste receptor, type 2, member 10
TBC1D17 TBC1 domain family, member 17
TMEM120B transmembrane protein 120B
TRIM21 tripartite motif containing 21
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VASH1 vasohibin 1
ZNF250 zinc finger protein 250
ZNF506 zinc finger protein 506
ZNF532 zinc finger protein 532
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862