alcuronium chloride-7345 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the alcuronium chloride-7345 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
APOE apolipoprotein E
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
AURKA aurora kinase A
BAHCC1 BAH domain and coiled-coil containing 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPRIN2 caprin family member 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CDA cytidine deaminase
CLCN6 chloride channel, voltage-sensitive 6
CLEC11A C-type lectin domain family 11, member A
CLUAP1 clusterin associated protein 1
CREB1 cAMP responsive element binding protein 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EGFL7 EGF-like-domain, multiple 7
EGR4 early growth response 4
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FAM120C family with sequence similarity 120C
FAM65A family with sequence similarity 65, member A
FBXL2 F-box and leucine-rich repeat protein 2
FER fer (fps/fes related) tyrosine kinase
FKBP10 FK506 binding protein 10, 65 kDa
FLJ21369 uncharacterized protein FLJ21369
FMO4 flavin containing monooxygenase 4
FOXO1 forkhead box O1
FRK fyn-related Src family tyrosine kinase
GEMIN8 gem (nuclear organelle) associated protein 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPC4 glypican 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRM8 glutamate receptor, metabotropic 8
HLA-C major histocompatibility complex, class I, C
HR hair growth associated
IFT27 intraflagellar transport 27
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
IRS2 insulin receptor substrate 2
ITGB5 integrin, beta 5
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KIAA0319L KIAA0319-like
KRT38 keratin 38, type I
LRRC14 leucine rich repeat containing 14
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCM3AP minichromosome maintenance complex component 3 associated protein
MCOLN1 mucolipin 1
MEGF9 multiple EGF-like-domains 9
NCOR2 nuclear receptor corepressor 2
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEK9 NIMA-related kinase 9
NEUROD4 neuronal differentiation 4
NF1 neurofibromin 1
NME5 NME/NM23 family member 5
NR2F1 nuclear receptor subfamily 2, group F, member 1
PCDHGA3 protocadherin gamma subfamily A, 3
PCNX pecanex homolog (Drosophila)
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA3 plexin A3
PRB4 proline-rich protein BstNI subfamily 4
PRPH peripherin
PVR poliovirus receptor
PXN paxillin
RAB11B RAB11B, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RASAL2 RAS protein activator like 2
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGS12 regulator of G-protein signaling 12
RND1 Rho family GTPase 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL7 ribosomal protein L7
RPS3A ribosomal protein S3A
RSU1 Ras suppressor protein 1
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BP2 SH3-domain binding protein 2
SOX9 SRY (sex determining region Y)-box 9
SPRR2B small proline-rich protein 2B
STMN1 stathmin 1
STMN4 stathmin-like 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM212 transmembrane protein 212
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNK1 tyrosine kinase, non-receptor, 1
TP63 tumor protein p63
TRIM62 tripartite motif containing 62
TSPAN9 tetraspanin 9
USB1 U6 snRNA biogenesis 1
WSB1 WD repeat and SOCS box containing 1
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF350 zinc finger protein 350
ZNF500 zinc finger protein 500
ZSCAN32 zinc finger and SCAN domain containing 32
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ANKRD36 ankyrin repeat domain 36
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ASAP1-IT1 ASAP1 intronic transcript 1
ATAD3A ATPase family, AAA domain containing 3A
C19ORF40 chromosome 19 open reading frame 40
CBX7 chromobox homolog 7
CGA glycoprotein hormones, alpha polypeptide
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNALI1 dynein, axonemal, light intermediate chain 1
ECHDC2 enoyl CoA hydratase domain containing 2
EFNA3 ephrin-A3
ENO2 enolase 2 (gamma, neuronal)
ERO1L ERO1-like (S. cerevisiae)
FAM134B family with sequence similarity 134, member B
FLJ11710 uncharacterized protein FLJ11710
GAN gigaxonin
GBP2 guanylate binding protein 2, interferon-inducible
GPC3 glypican 3
GUSBP3 glucuronidase, beta pseudogene 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HOXC10 homeobox C10
HP1BP3 heterochromatin protein 1, binding protein 3
HPS6 Hermansky-Pudlak syndrome 6
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
INCENP inner centromere protein antigens 135/155kDa
ITPKB inositol-trisphosphate 3-kinase B
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KIAA0513 KIAA0513
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LNPEP leucyl/cystinyl aminopeptidase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC37A2 leucine rich repeat containing 37, member A2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MED18 mediator complex subunit 18
MFSD11 major facilitator superfamily domain containing 11
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MXD3 MAX dimerization protein 3
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEK11 NIMA-related kinase 11
NES nestin
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NT5DC3 5'-nucleotidase domain containing 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUP62CL nucleoporin 62kDa C-terminal like
ONECUT2 one cut homeobox 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHB3 protocadherin beta 3
PGP phosphoglycolate phosphatase
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPRE protein tyrosine phosphatase, receptor type, E
RECQL4 RecQ protein-like 4
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC22A18 solute carrier family 22, member 18
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOWAHC sosondowah ankyrin repeat domain family member C
SP1 Sp1 transcription factor
STX1A syntaxin 1A (brain)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TARP TCR gamma alternate reading frame protein
TMEM120B transmembrane protein 120B
TMEM51 transmembrane protein 51
TRIM25 tripartite motif containing 25
TRIM5 tripartite motif containing 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWF2 twinfilin actin binding protein 2
ULBP2 UL16 binding protein 2
USP6NL USP6 N-terminal like
VASH1 vasohibin 1
VWA9 von Willebrand factor A domain containing 9
WDR44 WD repeat domain 44
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBED1 zinc finger, BED-type containing 1
ZNF141 zinc finger protein 141
ZNF16 zinc finger protein 16
ZNF227 zinc finger protein 227
ZNF510 zinc finger protein 510
ZNF571 zinc finger protein 571
ZNF862 zinc finger protein 862
ZSCAN31 zinc finger and SCAN domain containing 31
ZXDC ZXD family zinc finger C