aldosterone Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. (Chemical Entities of Biological Interest Ontology, CHEBI_27584)
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Genes

2 genes associated with the disease aldosterone in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
NR3C2 nuclear receptor subfamily 3, group C, member 2