alexander disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A leukodystrophy that is characterized by the destruction of white matter and the formation of Rosenthal fibers consisting of abnormal clumps of protein that accumulate in astrocytes. (Human Disease Ontology, DOID_4252)
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Genes

41 genes co-occuring with the disease alexander disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GFAP glial fibrillary acidic protein 2.33136
CRYAB crystallin, alpha B 2.22499
DES desmin 1.75233
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 1.24037
HSH2D hematopoietic SH2 domain containing 1.05093
MAP3K10 mitogen-activated protein kinase kinase kinase 10 1.01596
SYNM synemin, intermediate filament protein 0.877376
MAP3K13 mitogen-activated protein kinase kinase kinase 13 0.861409
BFSP2 beaded filament structural protein 2, phakinin 0.772479
MAP3K12 mitogen-activated protein kinase kinase kinase 12 0.770435
NLGN3 neuroligin 3 0.751678
GCLM glutamate-cysteine ligase, modifier subunit 0.619051
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.614356
HGFAC HGF activator 0.582773
COL4A1 collagen, type IV, alpha 1 0.545093
DNM2 dynamin 2 0.530768
ARSA arylsulfatase A 0.52729
GAN gigaxonin 0.450701
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.448441
LMNB1 lamin B1 0.440162
ASPA aspartoacylase 0.437154
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.431519
HDAC6 histone deacetylase 6 0.427015
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.419517
CRYAA crystallin, alpha A 0.394118
RICTOR RPTOR independent companion of MTOR, complex 2 0.378514
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.314278
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.31029
FABP3 fatty acid binding protein 3, muscle and heart 0.291539
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.271886
LAMA2 laminin, alpha 2 0.263014
AIF1 allograft inflammatory factor 1 0.239101
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.23353
CSF1R colony stimulating factor 1 receptor 0.232489
EDNRB endothelin receptor type B 0.212271
NFE2L2 nuclear factor, erythroid 2-like 2 0.189859
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.186811
HEXA hexosaminidase A (alpha polypeptide) 0.184424
TARDBP TAR DNA binding protein 0.180937
KRT14 keratin 14, type I 0.165435
LTA lymphotoxin alpha 0.159302