| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the alexidine-4721 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ALCAM | activated leukocyte cell adhesion molecule |
| APOLD1 | apolipoprotein L domain containing 1 |
| AREG | amphiregulin |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN1 | claudin 1 |
| CLTA | clathrin, light chain A |
| COL10A1 | collagen, type X, alpha 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DCLK2 | doublecortin-like kinase 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DUSP4 | dual specificity phosphatase 4 |
| EDN3 | endothelin 3 |
| EN2 | engrailed homeobox 2 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FGFR2 | fibroblast growth factor receptor 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GRB10 | growth factor receptor-bound protein 10 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HGD | homogentisate 1,2-dioxygenase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| HYAL4 | hyaluronoglucosaminidase 4 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL21R | interleukin 21 receptor |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLF9 | Kruppel-like factor 9 |
| KLHL24 | kelch-like family member 24 |
| LAMA4 | laminin, alpha 4 |
| LAMC2 | laminin, gamma 2 |
| LIF | leukemia inhibitory factor |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MED25 | mediator complex subunit 25 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta |
| NAV2 | neuron navigator 2 |
| NCLN | nicalin |
| NCOR2 | nuclear receptor corepressor 2 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NRL | neural retina leucine zipper |
| NRP1 | neuropilin 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OTC | ornithine carbamoyltransferase |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM2 | PR domain containing 2, with ZNF domain |
| RPL10L | ribosomal protein L10-like |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRIM14 | tripartite motif containing 14 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSSK2 | testis-specific serine kinase 2 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| ZNF280A | zinc finger protein 280A |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADCY6 | adenylate cyclase 6 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| B3GNT1 | |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C17ORF62 | chromosome 17 open reading frame 62 |
| CCNE1 | cyclin E1 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CENPC | centromere protein C |
| CERK | ceramide kinase |
| CHMP6 | charged multivesicular body protein 6 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLSPN | claspin |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DOLK | dolichol kinase |
| EFNA4 | ephrin-A4 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERCC6L | excision repair cross-complementation group 6-like |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM63A | family with sequence similarity 63, member A |
| FASTKD5 | FAST kinase domains 5 |
| FHOD1 | formin homology 2 domain containing 1 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GHR | growth hormone receptor |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HOXC11 | homeobox C11 |
| HOXC13 | homeobox C13 |
| HSPA2 | heat shock 70kDa protein 2 |
| IL17RA | interleukin 17 receptor A |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INTS9 | integrator complex subunit 9 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA0895 | KIAA0895 |
| LOC730101 | uncharacterized LOC730101 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LYRM9 | LYR motif containing 9 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MSX1 | msh homeobox 1 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PITX2 | paired-like homeodomain 2 |
| PLA2G15 | phospholipase A2, group XV |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLH | polymerase (DNA directed), eta |
| POLQ | polymerase (DNA directed), theta |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| PRKCD | protein kinase C, delta |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR15L | proline rich 15-like |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RNF121 | ring finger protein 121 |
| RWDD2A | RWD domain containing 2A |
| SALL2 | spalt-like transcription factor 2 |
| SCAP | SREBF chaperone |
| SETD6 | SET domain containing 6 |
| SH2B3 | SH2B adaptor protein 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 |
| SUOX | sulfite oxidase |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THOP1 | thimet oligopeptidase 1 |
| TMEM115 | transmembrane protein 115 |
| TMEM180 | transmembrane protein 180 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| VASH2 | vasohibin 2 |
| WDR19 | WD repeat domain 19 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF254 | zinc finger protein 254 |
| ZNF446 | zinc finger protein 446 |
| ZNF586 | zinc finger protein 586 |
| ZNF692 | zinc finger protein 692 |
| ZNF778 | zinc finger protein 778 |
