alexidine-7397 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the alexidine-7397 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
AGO4 argonaute RISC catalytic component 4
AQP3 aquaporin 3 (Gill blood group)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF7IP activating transcription factor 7 interacting protein
ATXN3 ataxin 3
BAIAP2 BAI1-associated protein 2
CABIN1 calcineurin binding protein 1
CARS cysteinyl-tRNA synthetase
CASS4 Cas scaffolding protein family member 4
CC2D1A coiled-coil and C2 domain containing 1A
CCDC85B coiled-coil domain containing 85B
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD6 CD6 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN6 chloride channel, voltage-sensitive 6
CRLF1 cytokine receptor-like factor 1
CTH cystathionine gamma-lyase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DISC1 disrupted in schizophrenia 1
DRP2 dystrophin related protein 2
EPYC epiphycan
EWSR1 EWS RNA-binding protein 1
GPR183 G protein-coupled receptor 183
GPR68 G protein-coupled receptor 68
GTPBP1 GTP binding protein 1
HIST1H3I histone cluster 1, H3i
HMOX1 heme oxygenase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IL11 interleukin 11
IL24 interleukin 24
IL33R interleukin 33 receptor
INSIG1 insulin induced gene 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLHL23 kelch-like family member 23
KLHL24 kelch-like family member 24
KRT6B keratin 6B, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LARP6 La ribonucleoprotein domain family, member 6
LRRK1 leucine-rich repeat kinase 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MARS methionyl-tRNA synthetase
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MUC1 mucin 1, cell surface associated
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NF1 neurofibromin 1
NKX3-2 NK3 homeobox 2
NLGN1 neuroligin 1
NUPR1 nuclear protein, transcriptional regulator, 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE4B phosphodiesterase 4B, cAMP-specific
PER1 period circadian clock 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRELP proline/arginine-rich end leucine-rich repeat protein
PRM2 protamine 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNX1 runt-related transcription factor 1
S100P S100 calcium binding protein P
SAMD4A sterile alpha motif domain containing 4A
SCIN scinderin
SKIL SKI-like proto-oncogene
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMC1A structural maintenance of chromosomes 1A
SOS2 son of sevenless homolog 2 (Drosophila)
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STC2 stanniocalcin 2
STEAP4 STEAP family member 4
SYT13 synaptotagmin XIII
TJAP1 tight junction associated protein 1 (peripheral)
TLR4 toll-like receptor 4
TMPRSS4 transmembrane protease, serine 4
TRIB3 tribbles pseudokinase 3
YTHDC1 YTH domain containing 1
ZNF428 zinc finger protein 428
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARRB2 arrestin, beta 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAG4 BCL2-associated athanogene 4
BCORL1 BCL6 corepressor-like 1
BHLHE41 basic helix-loop-helix family, member e41
BIRC3 baculoviral IAP repeat containing 3
BLM Bloom syndrome, RecQ helicase-like
BOLA1 bolA family member 1
C11ORF30 chromosome 11 open reading frame 30
C1ORF106 chromosome 1 open reading frame 106
C1ORF35 chromosome 1 open reading frame 35
CA5BP1 carbonic anhydrase VB pseudogene 1
CASP8AP2 caspase 8 associated protein 2
CCNE2 cyclin E2
CD83 CD83 molecule
CDC7 cell division cycle 7
CDH7 cadherin 7, type 2
DCAF4 DDB1 and CUL4 associated factor 4
DENND1B DENN/MADD domain containing 1B
DNA2 DNA replication helicase/nuclease 2
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EAF2 ELL associated factor 2
EFNA4 ephrin-A4
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM111A family with sequence similarity 111, member A
FAM114A2 family with sequence similarity 114, member A2
FBXO46 F-box protein 46
FZD3 frizzled class receptor 3
GJC1 gap junction protein, gamma 1, 45kDa
GRWD1 glutamate-rich WD repeat containing 1
HELLS helicase, lymphoid-specific
HOXB13 homeobox B13
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSPA2 heat shock 70kDa protein 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL7R interleukin 7 receptor
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JMJD4 jumonji domain containing 4
KLHL3 kelch-like family member 3
KLK6 kallikrein-related peptidase 6
KRT15 keratin 15, type I
LAS1L LAS1-like (S. cerevisiae)
LNPEP leucyl/cystinyl aminopeptidase
LOC730101 uncharacterized LOC730101
LPAR6 lysophosphatidic acid receptor 6
MFSD12 major facilitator superfamily domain containing 12
MOCS3 molybdenum cofactor synthesis 3
MPI mannose phosphate isomerase
MTERF1 mitochondrial transcription termination factor 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAT10 N-acetyltransferase 10 (GCN5-related)
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOP2 NOP2 nucleolar protein
PBX3 pre-B-cell leukemia homeobox 3
PEX26 peroxisomal biogenesis factor 26
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RANBP17 RAN binding protein 17
RANBP6 RAN binding protein 6
RPL13P5 ribosomal protein L13 pseudogene 5
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SALL2 spalt-like transcription factor 2
SETD6 SET domain containing 6
SETMAR SET domain and mariner transposase fusion gene
SIDT1 SID1 transmembrane family, member 1
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A40 solute carrier family 25, member 40
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SMAD5 SMAD family member 5
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPEG SPEG complex locus
TGFB3 transforming growth factor, beta 3
TMEM177 transmembrane protein 177
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSKU tsukushi, small leucine rich proteoglycan
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF14 zinc finger protein 14
ZNF175 zinc finger protein 175
ZNF204P zinc finger protein 204, pseudogene
ZNF318 zinc finger protein 318
ZNF33B zinc finger protein 33B
ZNF576 zinc finger protein 576
ZNF668 zinc finger protein 668
ZW10 zw10 kinetochore protein