| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alfadolone-7262 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AHI1 | Abelson helper integration site 1 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| APOA1 | apolipoprotein A-I |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRD4 | bromodomain containing 4 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CCDC181 | coiled-coil domain containing 181 |
| CCDC85C | coiled-coil domain containing 85C |
| CCPG1 | cell cycle progression 1 |
| CENPJ | centromere protein J |
| CIDEB | cell death-inducing DFFA-like effector b |
| CTAGE5 | CTAGE family, member 5 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EWSR1 | EWS RNA-binding protein 1 |
| FBN2 | fibrillin 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GPC3 | glypican 3 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GRM1 | glutamate receptor, metabotropic 1 |
| HDAC7 | histone deacetylase 7 |
| HOMER2 | homer scaffolding protein 2 |
| HOXA2 | homeobox A2 |
| INO80B | INO80 complex subunit B |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIAA0754 | KIAA0754 |
| KPNB1 | karyopherin (importin) beta 1 |
| KRT34 | keratin 34, type I |
| KYNU | kynureninase |
| LHX2 | LIM homeobox 2 |
| LOC647070 | uncharacterized LOC647070 |
| LY96 | lymphocyte antigen 96 |
| MAP1B | microtubule-associated protein 1B |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MPZL2 | myelin protein zero-like 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MT1E | metallothionein 1E |
| MTSS1L | metastasis suppressor 1-like |
| NABP1 | nucleic acid binding protein 1 |
| NF1 | neurofibromin 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NOP16 | NOP16 nucleolar protein |
| NRXN3 | neurexin 3 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PAX2 | paired box 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCM1 | pericentriolar material 1 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| RAB28 | RAB28, member RAS oncogene family |
| RNF39 | ring finger protein 39 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL10 | ribosomal protein L10 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| S100A3 | S100 calcium binding protein A3 |
| SCG2 | secretogranin II |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC46A3 | solute carrier family 46, member 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STK16 | serine/threonine kinase 16 |
| SYNGR1 | synaptogyrin 1 |
| TLK1 | tousled-like kinase 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM242 | transmembrane protein 242 |
| TPMT | thiopurine S-methyltransferase |
| TUBB2B | tubulin, beta 2B class IIb |
| WWC1 | WW and C2 domain containing 1 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF165 | zinc finger protein 165 |
| ZNF253 | zinc finger protein 253 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APH1B | APH1B gamma secretase subunit |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| AXIN1 | axin 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| C5 | complement component 5 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCNO | cyclin O |
| CDC37L1 | cell division cycle 37-like 1 |
| CENPQ | centromere protein Q |
| CEP72 | centrosomal protein 72kDa |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CLSPN | claspin |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCTN4 | dynactin 4 (p62) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EFNA4 | ephrin-A4 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM155A | family with sequence similarity 155, member A |
| FAM53B | family with sequence similarity 53, member B |
| FBXO2 | F-box protein 2 |
| FBXO46 | F-box protein 46 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| GLTP | glycolipid transfer protein |
| GSDMD | gasdermin D |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HHLA3 | HERV-H LTR-associating 3 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| JUNB | jun B proto-oncogene |
| LMBR1L | limb development membrane protein 1-like |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MCRS1 | microspherule protein 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MTRF1 | mitochondrial translational release factor 1 |
| MVP | major vault protein |
| NECAP2 | NECAP endocytosis associated 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PALMD | palmdelphin |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PUS1 | pseudouridylate synthase 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM38 | RNA binding motif protein 38 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SIRT2 | sirtuin 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| SYNC | syncoilin, intermediate filament protein |
| TAGLN3 | transgelin 3 |
| TCTN2 | tectonic family member 2 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM132A | transmembrane protein 132A |
| TMEM186 | transmembrane protein 186 |
| TMEM62 | transmembrane protein 62 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOR4A | torsin family 4, member A |
| TRIM66 | tripartite motif containing 66 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| XPC | xeroderma pigmentosum, complementation group C |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF212 | zinc finger protein 212 |
| ZNF227 | zinc finger protein 227 |
| ZNF230 | zinc finger protein 230 |
| ZNF273 | zinc finger protein 273 |
| ZNF813 | zinc finger protein 813 |
| ZXDC | ZXD family zinc finger C |
