| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the alfaxalone-3135 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| AHNAK | AHNAK nucleoprotein |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BMP7 | bone morphogenetic protein 7 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CADM4 | cell adhesion molecule 4 |
| CAPN9 | calpain 9 |
| CCDC181 | coiled-coil domain containing 181 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CFAP74 | cilia and flagella associated protein 74 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COL5A2 | collagen, type V, alpha 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CTSF | cathepsin F |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| DRD2 | dopamine receptor D2 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| E2F5 | E2F transcription factor 5, p130-binding |
| FAM127B | family with sequence similarity 127, member B |
| FN1 | fibronectin 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GDNF | glial cell derived neurotrophic factor |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPM6A | glycoprotein M6A |
| GPR153 | G protein-coupled receptor 153 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIST1H3I | histone cluster 1, H3i |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HSPA2 | heat shock 70kDa protein 2 |
| IFNA4 | interferon, alpha 4 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| INADL | InaD-like (Drosophila) |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLK7 | kallikrein-related peptidase 7 |
| LENEP | lens epithelial protein |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LOC100131532 | uncharacterized LOC100131532 |
| MAGEC1 | melanoma antigen family C1 |
| MAP4 | microtubule-associated protein 4 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MID1 | midline 1 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MUC1 | mucin 1, cell surface associated |
| MYO6 | myosin VI |
| NRG2 | neuregulin 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OLFML2A | olfactomedin-like 2A |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRDM9 | PR domain containing 9 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKCE | protein kinase C, epsilon |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAB6B | RAB6B, member RAS oncogene family |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RIN1 | Ras and Rab interactor 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SDS | serine dehydratase |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SH2D2A | SH2 domain containing 2A |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNAI1 | snail family zinc finger 1 |
| SNX24 | sorting nexin 24 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPON1 | spondin 1, extracellular matrix protein |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TBC1D22B | TBC1 domain family, member 22B |
| TCHH | trichohyalin |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TEF | thyrotrophic embryonic factor |
| THBS1 | thrombospondin 1 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TRD | T cell receptor delta locus |
| TSPAN6 | tetraspanin 6 |
| ULBP1 | UL16 binding protein 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| VCX2 | variable charge, X-linked 2 |
| ZNF407 | zinc finger protein 407 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ADORA3 | adenosine A3 receptor |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| AREL1 | apoptosis resistant E3 ubiquitin protein ligase 1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARMC7 | armadillo repeat containing 7 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CAPN15 | calpain 15 |
| CBX7 | chromobox homolog 7 |
| CCNT1 | cyclin T1 |
| CD180 | CD180 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD48 | CD48 molecule |
| CDCP1 | CUB domain containing protein 1 |
| CDK6 | cyclin-dependent kinase 6 |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CEP295 | centrosomal protein 295kDa |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CLDN15 | claudin 15 |
| CNTN1 | contactin 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FOXO4 | forkhead box O4 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALE | UDP-galactose-4-epimerase |
| GPATCH2L | G patch domain containing 2-like |
| HIST1H1T | histone cluster 1, H1t |
| HOXA5 | homeobox A5 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| MAK | male germ cell-associated kinase |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MKL2 | MKL/myocardin-like 2 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTCP1 | mature T-cell proliferation 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MTMR12 | myotubularin related protein 12 |
| NDE1 | nudE neurodevelopment protein 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POR | P450 (cytochrome) oxidoreductase |
| PRAF2 | PRA1 domain family, member 2 |
| QSER1 | glutamine and serine rich 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF121 | ring finger protein 121 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RWDD3 | RWD domain containing 3 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STAG3 | stromal antigen 3 |
| STBD1 | starch binding domain 1 |
| TESK1 | testis-specific kinase 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THBS3 | thrombospondin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRAF2 | TNF receptor-associated factor 2 |
| TUFT1 | tuftelin 1 |
| TWISTNB | TWIST neighbor |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF493 | zinc finger protein 493 |
| ZNF862 | zinc finger protein 862 |
