| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alfaxalone-5451 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ALS2CL | ALS2 C-terminal like |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANGPT4 | angiopoietin 4 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| ASB4 | ankyrin repeat and SOCS box containing 4 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP2K | BMP2 inducible kinase |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1RL | complement component 1, r subcomponent-like |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CAPN9 | calpain 9 |
| CCDC85C | coiled-coil domain containing 85C |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCNK | cyclin K |
| CD1A | CD1a molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| COL1A1 | collagen, type I, alpha 1 |
| COL5A1 | collagen, type V, alpha 1 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DSC3 | desmocollin 3 |
| EGFR | epidermal growth factor receptor |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EMP1 | epithelial membrane protein 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| EPHA1 | EPH receptor A1 |
| EXOSC1 | exosome component 1 |
| EXOSC2 | exosome component 2 |
| FAM46C | family with sequence similarity 46, member C |
| FOXG1 | forkhead box G1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GHRHR | growth hormone releasing hormone receptor |
| GK | glycerol kinase |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GYPB | glycophorin B (MNS blood group) |
| HCRT | hypocretin (orexin) neuropeptide precursor |
| HDAC7 | histone deacetylase 7 |
| HFE | hemochromatosis |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4E | histone cluster 1, H4e |
| IFI6 | interferon, alpha-inducible protein 6 |
| INHBE | inhibin, beta E |
| JAK3 | Janus kinase 3 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAMC2 | laminin, gamma 2 |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LRP1B | low density lipoprotein receptor-related protein 1B |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MYEF2 | myelin expression factor 2 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NF1 | neurofibromin 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIGR | polymeric immunoglobulin receptor |
| PNLIPRP2 | pancreatic lipase-related protein 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| S100A8 | S100 calcium binding protein A8 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STK17B | serine/threonine kinase 17b |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM246 | transmembrane protein 246 |
| TRAV8-3 | T cell receptor alpha variable 8-3 |
| TSC22D4 | TSC22 domain family, member 4 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UTRN | utrophin |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VN1R1 | vomeronasal 1 receptor 1 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF551 | zinc finger protein 551 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADCY6 | adenylate cyclase 6 |
| ADCY7 | adenylate cyclase 7 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALPK1 | alpha-kinase 1 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC4 | armadillo repeat containing 4 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B9D2 | B9 protein domain 2 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CARF | calcium responsive transcription factor |
| CBR4 | carbonyl reductase 4 |
| CBX8 | chromobox homolog 8 |
| CCDC121 | coiled-coil domain containing 121 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRLF1 | cytokine receptor-like factor 1 |
| CRY2 | cryptochrome circadian clock 2 |
| DBF4B | DBF4 zinc finger B |
| DENND4A | DENN/MADD domain containing 4A |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EMID1 | EMI domain containing 1 |
| ERCC6 | excision repair cross-complementation group 6 |
| FAM110B | family with sequence similarity 110, member B |
| FBXO4 | F-box protein 4 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HHAT | hedgehog acyltransferase |
| HIST1H4A | histone cluster 1, H4a |
| IL17RA | interleukin 17 receptor A |
| INO80D | INO80 complex subunit D |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LEFTY1 | left-right determination factor 1 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMNB1 | lamin B1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUC3A | mucin 3A, cell surface associated |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NIPAL2 | NIPA-like domain containing 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PDE12 | phosphodiesterase 12 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLD3 | phospholipase D family, member 3 |
| PRR14L | proline rich 14-like |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTK6 | protein tyrosine kinase 6 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMHD1 | SAM domain and HD domain 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SIRT6 | sirtuin 6 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPATA7 | spermatogenesis associated 7 |
| STRA6 | stimulated by retinoic acid 6 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TARP | TCR gamma alternate reading frame protein |
| THAP7 | THAP domain containing 7 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMC5 | transmembrane channel-like 5 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAIP | TRAF interacting protein |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBA3C | tubulin, alpha 3c |
| ULBP2 | UL16 binding protein 2 |
| WDR4 | WD repeat domain 4 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF557 | zinc finger protein 557 |
| ZNF804A | zinc finger protein 804A |
| ZNF816 | zinc finger protein 816 |
