| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alfaxalone-6514 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTN2 | actinin, alpha 2 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AJAP1 | adherens junctions associated protein 1 |
| AK2 | adenylate kinase 2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANK1 | ankyrin 1, erythrocytic |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CA4 | carbonic anhydrase IV |
| CALD1 | caldesmon 1 |
| CAMKV | CaM kinase-like vesicle-associated |
| CCDC81 | coiled-coil domain containing 81 |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CD1C | CD1c molecule |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| COL6A1 | collagen, type VI, alpha 1 |
| COL8A2 | collagen, type VIII, alpha 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DENND1C | DENN/MADD domain containing 1C |
| DENND3 | DENN/MADD domain containing 3 |
| DTNA | dystrobrevin, alpha |
| EDA | ectodysplasin A |
| EML2 | echinoderm microtubule associated protein like 2 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM46C | family with sequence similarity 46, member C |
| FBXO41 | F-box protein 41 |
| FDPS | farnesyl diphosphate synthase |
| FGA | fibrinogen alpha chain |
| FGF2 | fibroblast growth factor 2 (basic) |
| FHL1 | four and a half LIM domains 1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GLS | glutaminase |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HES2 | hes family bHLH transcription factor 2 |
| HOXA7 | homeobox A7 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KLHL29 | kelch-like family member 29 |
| LAMA4 | laminin, alpha 4 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAX | MYC associated factor X |
| MBD3 | methyl-CpG binding domain protein 3 |
| MSI1 | musashi RNA-binding protein 1 |
| MSR1 | macrophage scavenger receptor 1 |
| MST1 | macrophage stimulating 1 |
| MYO1B | myosin IB |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NUDCD3 | NudC domain containing 3 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OR6A2 | olfactory receptor, family 6, subfamily A, member 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PCDHB13 | protocadherin beta 13 |
| PDLIM3 | PDZ and LIM domain 3 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PKP1 | plakophilin 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PROX1 | prospero homeobox 1 |
| RARG | retinoic acid receptor, gamma |
| RCAN1 | regulator of calcineurin 1 |
| RGS6 | regulator of G-protein signaling 6 |
| SBF1 | SET binding factor 1 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SYNJ2 | synaptojanin 2 |
| TAPBP | TAP binding protein (tapasin) |
| TCF20 | transcription factor 20 (AR1) |
| TLK1 | tousled-like kinase 1 |
| TUBA3C | tubulin, alpha 3c |
| ULBP1 | UL16 binding protein 1 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZNF318 | zinc finger protein 318 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADM | adrenomedullin |
| AOX1 | aldehyde oxidase 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| AZI2 | 5-azacytidine induced 2 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C5AR2 | complement component 5a receptor 2 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CCP110 | centriolar coiled coil protein 110kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDND1 | claudin domain containing 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNN2 | calponin 2 |
| CUEDC1 | CUE domain containing 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DOC2A | double C2-like domains, alpha |
| EAF2 | ELL associated factor 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM120C | family with sequence similarity 120C |
| FAM155A | family with sequence similarity 155, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO22 | F-box protein 22 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIRA | histone cell cycle regulator |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA4 | homeobox A4 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| ITGA6 | integrin, alpha 6 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KLHL12 | kelch-like family member 12 |
| KLHL25 | kelch-like family member 25 |
| LENEP | lens epithelial protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MUC3A | mucin 3A, cell surface associated |
| MXD3 | MAX dimerization protein 3 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NXPH4 | neurexophilin 4 |
| ONECUT2 | one cut homeobox 2 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMCH | pro-melanin-concentrating hormone |
| RASA2 | RAS p21 protein activator 2 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPGRIP1L | RPGRIP1-like |
| SAV1 | salvador family WW domain containing protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCHIP1 | schwannomin interacting protein 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SECTM1 | secreted and transmembrane 1 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC46A3 | solute carrier family 46, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| STON1 | stonin 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYCP2 | synaptonemal complex protein 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TSPAN2 | tetraspanin 2 |
| UPP1 | uridine phosphorylase 1 |
| VIM | vimentin |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF586 | zinc finger protein 586 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
