| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alfuzosin-1586 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ANKRD12 | ankyrin repeat domain 12 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| ATP9B | ATPase, class II, type 9B |
| ATR | ATR serine/threonine kinase |
| ATXN7 | ataxin 7 |
| AZI2 | 5-azacytidine induced 2 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| CD164 | CD164 molecule, sialomucin |
| CD300A | CD300a molecule |
| CD69 | CD69 molecule |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRCP | CGRP receptor component |
| CTSS | cathepsin S |
| CYB561 | cytochrome b561 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DUSP2 | dual specificity phosphatase 2 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EIF4E | eukaryotic translation initiation factor 4E |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| ITM2B | integral membrane protein 2B |
| JUN | jun proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLHL20 | kelch-like family member 20 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KTN1 | kinectin 1 (kinesin receptor) |
| LACTB2 | lactamase, beta 2 |
| LPIN2 | lipin 2 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MEGF6 | multiple EGF-like-domains 6 |
| MTMR6 | myotubularin related protein 6 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MX1 | MX dynamin-like GTPase 1 |
| MYL10 | myosin, light chain 10, regulatory |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NCOA3 | nuclear receptor coactivator 3 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PCGF1 | polycomb group ring finger 1 |
| PLK4 | polo-like kinase 4 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| POLI | polymerase (DNA directed) iota |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RAD17 | RAD17 homolog (S. pombe) |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RB1 | retinoblastoma 1 |
| RGS1 | regulator of G-protein signaling 1 |
| RGS13 | regulator of G-protein signaling 13 |
| RGS16 | regulator of G-protein signaling 16 |
| RHOH | ras homolog family member H |
| RHOT2 | ras homolog family member T2 |
| RIOK3 | RIO kinase 3 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL7 | ribosomal protein L7 |
| RPS2 | ribosomal protein S2 |
| RPS9 | ribosomal protein S9 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SMAD7 | SMAD family member 7 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPP1 | secreted phosphoprotein 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAG2 | stromal antigen 2 |
| STRN3 | striatin, calmodulin binding protein 3 |
| SUMO1 | small ubiquitin-like modifier 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TANK | TRAF family member-associated NFKB activator |
| TBC1D30 | TBC1 domain family, member 30 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TPR | translocated promoter region, nuclear basket protein |
| TRAPPC11 | trafficking protein particle complex 11 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTC37 | tetratricopeptide repeat domain 37 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TUBA4B | tubulin, alpha 4b |
| UBQLN4 | ubiquilin 4 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 |
| WDR48 | WD repeat domain 48 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADORA3 | adenosine A3 receptor |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| BRD9 | bromodomain containing 9 |
| C11ORF49 | chromosome 11 open reading frame 49 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEP170B | centrosomal protein 170B |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CFL1 | cofilin 1 (non-muscle) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| CPNE1 | copine I |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DAD1 | defender against cell death 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| ERCC2 | excision repair cross-complementation group 2 |
| GPS1 | G protein pathway suppressor 1 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| ICE2 | interactor of little elongation complex ELL subunit 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IL2RG | interleukin 2 receptor, gamma |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KIF13B | kinesin family member 13B |
| LCT | lactase |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LSP1 | lymphocyte-specific protein 1 |
| LUC7L | LUC7-like (S. cerevisiae) |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MKKS | McKusick-Kaufman syndrome |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MRPL4 | mitochondrial ribosomal protein L4 |
| MRPS34 | mitochondrial ribosomal protein S34 |
| NABP2 | nucleic acid binding protein 2 |
| NBAS | neuroblastoma amplified sequence |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
| NOTCH1 | notch 1 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NRD1 | nardilysin (N-arginine dibasic convertase) |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NUP93 | nucleoporin 93kDa |
| OIP5 | Opa interacting protein 5 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSGEP | O-sialoglycoprotein endopeptidase |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK1IP1 | PAK1 interacting protein 1 |
| PALM | paralemmin |
| PANK4 | pantothenate kinase 4 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCTP | phosphatidylcholine transfer protein |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PSKH1 | protein serine kinase H1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RANGAP1 | Ran GTPase activating protein 1 |
| RASA2 | RAS p21 protein activator 2 |
| RBM15B | RNA binding motif protein 15B |
| RNF113A | ring finger protein 113A |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SAMHD1 | SAM domain and HD domain 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24C | SEC24 family member C |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| THBS4 | thrombospondin 4 |
| THG1L | tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) |
| THOP1 | thimet oligopeptidase 1 |
| TMEM109 | transmembrane protein 109 |
| USB1 | U6 snRNA biogenesis 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| YIPF1 | Yip1 domain family, member 1 |
| ZNF189 | zinc finger protein 189 |
| ZNF536 | zinc finger protein 536 |
| ZNF671 | zinc finger protein 671 |
