| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the alfuzosin-4644 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACRV1 | acrosomal vesicle protein 1 |
| AHSG | alpha-2-HS-glycoprotein |
| ANGPT4 | angiopoietin 4 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| APOBR | apolipoprotein B receptor |
| ARTN | artemin |
| BCL3 | B-cell CLL/lymphoma 3 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CACYBP | calcyclin binding protein |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC14B | cell division cycle 14B |
| CDX1 | caudal type homeobox 1 |
| CFAP46 | cilia and flagella associated protein 46 |
| CHN2 | chimerin 2 |
| CLMN | calmin (calponin-like, transmembrane) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| DCX | doublecortin |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DENND1C | DENN/MADD domain containing 1C |
| DOCK9 | dedicator of cytokinesis 9 |
| DSC2 | desmocollin 2 |
| EDA | ectodysplasin A |
| ELL | elongation factor RNA polymerase II |
| EPB42 | erythrocyte membrane protein band 4.2 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM163A | family with sequence similarity 163, member A |
| FBRS | fibrosin |
| FBXO22 | F-box protein 22 |
| FGB | fibrinogen beta chain |
| FGFR1 | fibroblast growth factor receptor 1 |
| GPR135 | G protein-coupled receptor 135 |
| GSTA1 | glutathione S-transferase alpha 1 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXD1 | homeobox D1 |
| IAPP | islet amyloid polypeptide |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| ING2 | inhibitor of growth family, member 2 |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KIAA0125 | KIAA0125 |
| KIF21B | kinesin family member 21B |
| KRT83 | keratin 83, type II |
| LENEP | lens epithelial protein |
| LIPE | lipase, hormone-sensitive |
| LOC100131532 | uncharacterized LOC100131532 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LST1 | leukocyte specific transcript 1 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MMP11 | matrix metallopeptidase 11 |
| MORN1 | MORN repeat containing 1 |
| MRAS | muscle RAS oncogene homolog |
| NCAM1 | neural cell adhesion molecule 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NIPAL2 | NIPA-like domain containing 2 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| ONECUT2 | one cut homeobox 2 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PCDHGA11 | protocadherin gamma subfamily A, 11 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDPN | podoplanin |
| PITX1 | paired-like homeodomain 1 |
| PLXNC1 | plexin C1 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PYY | peptide YY |
| RAG2 | recombination activating gene 2 |
| RBBP4 | retinoblastoma binding protein 4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPANXC | SPANX family, member C |
| SPTB | spectrin, beta, erythrocytic |
| SUSD4 | sushi domain containing 4 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBX1 | T-box 1 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TGM4 | transglutaminase 4 |
| TPSAB1 | tryptase alpha/beta 1 |
| TTN | titin |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF214 | zinc finger protein 214 |
| ZNF507 | zinc finger protein 507 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ABHD8 | abhydrolase domain containing 8 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADCY6 | adenylate cyclase 6 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ALPK1 | alpha-kinase 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CD68 | CD68 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CENPJ | centromere protein J |
| CEP112 | centrosomal protein 112kDa |
| CEP131 | centrosomal protein 131kDa |
| CEP85 | centrosomal protein 85kDa |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CHM | choroideremia (Rab escort protein 1) |
| CHMP6 | charged multivesicular body protein 6 |
| CLDN1 | claudin 1 |
| CLDND1 | claudin domain containing 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTLN | centlein, centrosomal protein |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DIXDC1 | DIX domain containing 1 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EN1 | engrailed homeobox 1 |
| EVPL | envoplakin |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FA2H | fatty acid 2-hydroxylase |
| FANCE | Fanconi anemia, complementation group E |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FHOD1 | formin homology 2 domain containing 1 |
| FMO4 | flavin containing monooxygenase 4 |
| FUZ | fuzzy planar cell polarity protein |
| FZD8 | frizzled class receptor 8 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR39 | G protein-coupled receptor 39 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HDAC5 | histone deacetylase 5 |
| HDAC7 | histone deacetylase 7 |
| HELZ | helicase with zinc finger |
| HOXA1 | homeobox A1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IL6 | interleukin 6 |
| IPO8 | importin 8 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIFAP3 | kinesin-associated protein 3 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MX1 | MX dynamin-like GTPase 1 |
| NCS1 | neuronal calcium sensor 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NRBP1 | nuclear receptor binding protein 1 |
| OLFML2A | olfactomedin-like 2A |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PALMD | palmdelphin |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRSS8 | protease, serine, 8 |
| RAB5B | RAB5B, member RAS oncogene family |
| RBM38 | RNA binding motif protein 38 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERTAD3 | SERTA domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC35F6 | solute carrier family 35, member F6 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STK16 | serine/threonine kinase 16 |
| TCTN2 | tectonic family member 2 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM120B | transmembrane protein 120B |
| TMEM8A | transmembrane protein 8A |
| TNRC6B | trinucleotide repeat containing 6B |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM25 | tripartite motif containing 25 |
| TRIM45 | tripartite motif containing 45 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TXLNG | taxilin gamma |
| UNC119 | unc-119 homolog (C. elegans) |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR76 | WD repeat domain 76 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF254 | zinc finger protein 254 |
