| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the alfuzosin-5242 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARSD | arylsulfatase D |
| CADM3 | cell adhesion molecule 3 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD22 | CD22 molecule |
| CD300C | CD300c molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CFAP70 | cilia and flagella associated protein 70 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CRAT | carnitine O-acetyltransferase |
| CTIF | CBP80/20-dependent translation initiation factor |
| CTSF | cathepsin F |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DMXL2 | Dmx-like 2 |
| EFNB3 | ephrin-B3 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EPX | eosinophil peroxidase |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBXO41 | F-box protein 41 |
| GGT1 | gamma-glutamyltransferase 1 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2AJ | histone cluster 1, H2aj |
| IRS2 | insulin receptor substrate 2 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KRT37 | keratin 37, type I |
| KSR1 | kinase suppressor of ras 1 |
| LAG3 | lymphocyte-activation gene 3 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MCAM | melanoma cell adhesion molecule |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MST1 | macrophage stimulating 1 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OR7A5 | olfactory receptor, family 7, subfamily A, member 5 |
| PCDH17 | protocadherin 17 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAT | plasminogen activator, tissue |
| PLCL2 | phospholipase C-like 2 |
| PLSCR4 | phospholipid scramblase 4 |
| PML | promyelocytic leukemia |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKCA | protein kinase C, alpha |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RDH8 | retinol dehydrogenase 8 (all-trans) |
| RPLP2 | ribosomal protein, large, P2 |
| S100B | S100 calcium binding protein B |
| SDC3 | syndecan 3 |
| SIX3 | SIX homeobox 3 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| UNC119 | unc-119 homolog (C. elegans) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VRTN | vertebrae development associated |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADRA2C | adrenoceptor alpha 2C |
| ALPK1 | alpha-kinase 1 |
| AMT | aminomethyltransferase |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CA11 | carbonic anhydrase XI |
| CD302 | CD302 molecule |
| CES3 | carboxylesterase 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLGN | calmegin |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DMTN | dematin actin binding protein |
| EFHD2 | EF-hand domain family, member D2 |
| ETV6 | ets variant 6 |
| F2R | coagulation factor II (thrombin) receptor |
| FANCE | Fanconi anemia, complementation group E |
| FFAR2 | free fatty acid receptor 2 |
| FGF13 | fibroblast growth factor 13 |
| FRK | fyn-related Src family tyrosine kinase |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GK3P | glycerol kinase 3 pseudogene |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HMOX1 | heme oxygenase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IPO13 | importin 13 |
| IPO8 | importin 8 |
| IQCG | IQ motif containing G |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMB3 | laminin, beta 3 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC100272216 | uncharacterized LOC100272216 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCC | mutated in colorectal cancers |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MPI | mannose phosphate isomerase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MXD3 | MAX dimerization protein 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCDHA5 | protocadherin alpha 5 |
| PCDHB13 | protocadherin beta 13 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB36 | RAB36, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF31 | ring finger protein 31 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A7 | S100 calcium binding protein A7 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPIDR | scaffolding protein involved in DNA repair |
| STBD1 | starch binding domain 1 |
| STRN | striatin, calmodulin binding protein |
| SYNGR3 | synaptogyrin 3 |
| TEP1 | telomerase-associated protein 1 |
| TMEM132A | transmembrane protein 132A |
| TMEM242 | transmembrane protein 242 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM21 | tripartite motif containing 21 |
| TRIM36 | tripartite motif containing 36 |
| TWF2 | twinfilin actin binding protein 2 |
| VLDLR | very low density lipoprotein receptor |
| VPS9D1 | VPS9 domain containing 1 |
| WDR4 | WD repeat domain 4 |
| YY2 | YY2 transcription factor |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF34 | zinc finger protein 34 |
| ZNF573 | zinc finger protein 573 |
| ZNF652 | zinc finger protein 652 |
