| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alfuzosin-5605 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY2 | adenylate cyclase 2 (brain) |
| ADRA1D | adrenoceptor alpha 1D |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ANK1 | ankyrin 1, erythrocytic |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| BMP6 | bone morphogenetic protein 6 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CA4 | carbonic anhydrase IV |
| CACTIN | cactin, spliceosome C complex subunit |
| CCDC28B | coiled-coil domain containing 28B |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD72 | CD72 molecule |
| CHN2 | chimerin 2 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CUL7 | cullin 7 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DIO2 | deiodinase, iodothyronine, type II |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EFNB3 | ephrin-B3 |
| EPHB2 | EPH receptor B2 |
| EPOR | erythropoietin receptor |
| EVA1B | eva-1 homolog B (C. elegans) |
| FABP7 | fatty acid binding protein 7, brain |
| FAM13C | family with sequence similarity 13, member C |
| FAM153A | family with sequence similarity 153, member A |
| FAM163A | family with sequence similarity 163, member A |
| FZD5 | frizzled class receptor 5 |
| GAS1 | growth arrest-specific 1 |
| GRB10 | growth factor receptor-bound protein 10 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTP1 | glutathione S-transferase pi 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KLHL25 | kelch-like family member 25 |
| KLHL35 | kelch-like family member 35 |
| KRT17 | keratin 17, type I |
| KSR1 | kinase suppressor of ras 1 |
| LAMA4 | laminin, alpha 4 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LMTK1 | lemur tail kinase 1 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 |
| LTB4R | leukotriene B4 receptor |
| MAPK7 | mitogen-activated protein kinase 7 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MTCP1 | mature T-cell proliferation 1 |
| MYO15A | myosin XVA |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NCAM1 | neural cell adhesion molecule 1 |
| OBSL1 | obscurin-like 1 |
| OGFR | opioid growth factor receptor |
| OR1F2P | olfactory receptor, family 1, subfamily F, member 2, pseudogene |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDH12 | protocadherin 12 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PLSCR2 | phospholipid scramblase 2 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| POLL | polymerase (DNA directed), lambda |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRAMEF12 | PRAME family member 12 |
| PRR4 | proline rich 4 (lacrimal) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB11B | RAB11B, member RAS oncogene family |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RBBP4 | retinoblastoma binding protein 4 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RUNX1 | runt-related transcription factor 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIRT4 | sirtuin 4 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SPN | sialophorin |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| TAZ | tafazzin |
| TBX5 | T-box 5 |
| TCP11 | t-complex 11, testis-specific |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| UCN | urocortin |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VGF | VGF nerve growth factor inducible |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF177 | zinc finger protein 177 |
| ZNF345 | zinc finger protein 345 |
| ZNF440 | zinc finger protein 440 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| AMT | aminomethyltransferase |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| AXIN1 | axin 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC88C | coiled-coil domain containing 88C |
| CD34 | CD34 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLGN | calmegin |
| CTAGE9 | CTAGE family, member 9 |
| DOCK4 | dedicator of cytokinesis 4 |
| DSPP | dentin sialophosphoprotein |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EFNA3 | ephrin-A3 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FRMD1 | FERM domain containing 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR19 | G protein-coupled receptor 19 |
| GPR27 | G protein-coupled receptor 27 |
| GPR3 | G protein-coupled receptor 3 |
| HDAC5 | histone deacetylase 5 |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4E | histone cluster 1, H4e |
| INCENP | inner centromere protein antigens 135/155kDa |
| INO80D | INO80 complex subunit D |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0319L | KIAA0319-like |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCRS1 | microspherule protein 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MSI1 | musashi RNA-binding protein 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO1F | myosin IF |
| NBEAL2 | neurobeachin-like 2 |
| NEK11 | NIMA-related kinase 11 |
| NKX3-2 | NK3 homeobox 2 |
| NPTX1 | neuronal pentraxin I |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCDHA6 | protocadherin alpha 6 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PER3 | period circadian clock 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRSS16 | protease, serine, 16 (thymus) |
| RAB30 | RAB30, member RAS oncogene family |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF121 | ring finger protein 121 |
| RNF122 | ring finger protein 122 |
| RPL10L | ribosomal protein L10-like |
| RUNDC3B | RUN domain containing 3B |
| S100A2 | S100 calcium binding protein A2 |
| S100A6 | S100 calcium binding protein A6 |
| S100A7 | S100 calcium binding protein A7 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SH2D4A | SH2 domain containing 4A |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SPAG4 | sperm associated antigen 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TBC1D17 | TBC1 domain family, member 17 |
| TBX19 | T-box 19 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM180 | transmembrane protein 180 |
| TMEM242 | transmembrane protein 242 |
| TMEM45A | transmembrane protein 45A |
| TMEM53 | transmembrane protein 53 |
| TSGA10 | testis specific, 10 |
| UPK3B | uroplakin 3B |
| ZNF136 | zinc finger protein 136 |
| ZNF227 | zinc finger protein 227 |
| ZNF484 | zinc finger protein 484 |
| ZNF573 | zinc finger protein 573 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZW10 | zw10 kinetochore protein |
