alimemazine-2736 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the alimemazine-2736 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALDOB aldolase B, fructose-bisphosphate
ALOX15B arachidonate 15-lipoxygenase, type B
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOA4 apolipoprotein A-IV
C11ORF16 chromosome 11 open reading frame 16
C11ORF80 chromosome 11 open reading frame 80
C9ORF9 chromosome 9 open reading frame 9
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCL19 chemokine (C-C motif) ligand 19
CD6 CD6 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEMP1 cementum protein 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNTNAP2 contactin associated protein-like 2
CSHL1 chorionic somatomammotropin hormone-like 1
CST1 cystatin SN
DSCAM Down syndrome cell adhesion molecule
EHD2 EH-domain containing 2
FAM106A family with sequence similarity 106, member A
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GATA4 GATA binding protein 4
GLRA2 glycine receptor, alpha 2
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRM8 glutamate receptor, metabotropic 8
GUCA2A guanylate cyclase activator 2A (guanylin)
H2AFJ H2A histone family, member J
HEG1 heart development protein with EGF-like domains 1
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BN histone cluster 1, H2bn
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXD10 homeobox D10
HPR haptoglobin-related protein
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IGHA1 immunoglobulin heavy constant alpha 1
IGHM immunoglobulin heavy constant mu
IL12B interleukin 12B
IL1RN interleukin 1 receptor antagonist
IL7R interleukin 7 receptor
INHBA inhibin, beta A
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAP7 microtubule-associated protein 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MSX2 msh homeobox 2
MYLK myosin light chain kinase
MYO6 myosin VI
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NLGN1 neuroligin 1
NRG1 neuregulin 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OCM2 oncomodulin 2
PAPOLB poly(A) polymerase beta (testis specific)
PCDHGB6 protocadherin gamma subfamily B, 6
PDE4DIP phosphodiesterase 4D interacting protein
PICALM phosphatidylinositol binding clathrin assembly protein
PKP2 plakophilin 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCH1 phospholipase C, eta 1
POLH polymerase (DNA directed), eta
PPAP2B phosphatidic acid phosphatase type 2B
PRB1 proline-rich protein BstNI subfamily 1
PSG1 pregnancy specific beta-1-glycoprotein 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RBP3 retinol binding protein 3, interstitial
RGS12 regulator of G-protein signaling 12
SCAND2P SCAN domain containing 2 pseudogene
SFTPA2 surfactant protein A2
SIM2 single-minded family bHLH transcription factor 2
SIX3 SIX homeobox 3
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRPK3 SRSF protein kinase 3
SSX1 synovial sarcoma, X breakpoint 1
STATH statherin
TBX5 T-box 5
TGFB1 transforming growth factor, beta 1
TMEM212 transmembrane protein 212
TNP2 transition protein 2 (during histone to protamine replacement)
TSKU tsukushi, small leucine rich proteoglycan
UBE3A ubiquitin protein ligase E3A
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACBD4 acyl-CoA binding domain containing 4
ACVR2B activin A receptor, type IIB
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOLD1 apolipoprotein L domain containing 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
AXIN1 axin 1
C16ORF45 chromosome 16 open reading frame 45
CCDC132 coiled-coil domain containing 132
CCDC57 coiled-coil domain containing 57
CCDC71 coiled-coil domain containing 71
CFP complement factor properdin
CLCN5 chloride channel, voltage-sensitive 5
CTRL chymotrypsin-like
CTSD cathepsin D
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPDC5 DEP domain containing 5
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
ENO3 enolase 3 (beta, muscle)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM118A family with sequence similarity 118, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FOXO4 forkhead box O4
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GK3P glycerol kinase 3 pseudogene
GPATCH2L G patch domain containing 2-like
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H1E histone cluster 1, H1e
ICAM5 intercellular adhesion molecule 5, telencephalin
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INO80D INO80 complex subunit D
IPO8 importin 8
IPP intracisternal A particle-promoted polypeptide
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0753 KIAA0753
KLF3 Kruppel-like factor 3 (basic)
LHFPL2 lipoma HMGIC fusion partner-like 2
LRP2 low density lipoprotein receptor-related protein 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MTCP1 mature T-cell proliferation 1
MXD3 MAX dimerization protein 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NINJ2 ninjurin 2
NNAT neuronatin
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OXCT2 3-oxoacid CoA transferase 2
PADI2 peptidyl arginine deiminase, type II
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDHGA8 protocadherin gamma subfamily A, 8
PCDHGB5 protocadherin gamma subfamily B, 5
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIR pirin (iron-binding nuclear protein)
PLA2G12A phospholipase A2, group XIIA
PLD3 phospholipase D family, member 3
PRAMEF11 PRAME family member 11
PRR7 proline rich 7 (synaptic)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
REC8 REC8 meiotic recombination protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RELN reelin
RFPL3S RFPL3 antisense
RGS19 regulator of G-protein signaling 19
RHOB ras homolog family member B
RPL10L ribosomal protein L10-like
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A6 solute carrier family 16, member 6
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPAG1 sperm associated antigen 1
SPATA2L spermatogenesis associated 2-like
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
STX1A syntaxin 1A (brain)
SUSD5 sushi domain containing 5
THEM6 thioesterase superfamily member 6
THRAP3 thyroid hormone receptor associated protein 3
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOM1 target of myb1 (chicken)
TOR4A torsin family 4, member A
TTLL1 tubulin tyrosine ligase-like family member 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP6NL USP6 N-terminal like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XYLT2 xylosyltransferase II
ZFHX4 zinc finger homeobox 4
ZNF225 zinc finger protein 225
ZNF34 zinc finger protein 34
ZNF675 zinc finger protein 675
ZNF778 zinc finger protein 778
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2