alimemazine-5881 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the alimemazine-5881 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
AGO4 argonaute RISC catalytic component 4
AGRP agouti related neuropeptide
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ART1 ADP-ribosyltransferase 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BIRC3 baculoviral IAP repeat containing 3
BMP8A bone morphogenetic protein 8a
C10ORF12 chromosome 10 open reading frame 12
CA9 carbonic anhydrase IX
CASP5 caspase 5, apoptosis-related cysteine peptidase
CFHR2 complement factor H-related 2
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CPNE7 copine VII
CRLF2 cytokine receptor-like factor 2
CYTH3 cytohesin 3
DCTN2 dynactin 2 (p50)
DDIT3 DNA-damage-inducible transcript 3
DENND3 DENN/MADD domain containing 3
ELSPBP1 epididymal sperm binding protein 1
EMX1 empty spiracles homeobox 1
FAM198B family with sequence similarity 198, member B
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FOXN2 forkhead box N2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GLP1R glucagon-like peptide 1 receptor
GNS glucosamine (N-acetyl)-6-sulfatase
GPRC5B G protein-coupled receptor, class C, group 5, member B
HAUS5 HAUS augmin-like complex, subunit 5
HDAC5 histone deacetylase 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HFE hemochromatosis
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IFNB1 interferon, beta 1, fibroblast
INHBA inhibin, beta A
IPO8 importin 8
JUND jun D proto-oncogene
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KLHL25 kelch-like family member 25
KLK13 kallikrein-related peptidase 13
KRIT1 KRIT1, ankyrin repeat containing
KRT34 keratin 34, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LOC729164 hCG1732469
MAL mal, T-cell differentiation protein
MFGE8 milk fat globule-EGF factor 8 protein
MMP13 matrix metallopeptidase 13
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR11 myotubularin related protein 11
MYBPC2 myosin binding protein C, fast type
NDRG1 N-myc downstream regulated 1
NF2 neurofibromin 2 (merlin)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NIPAL2 NIPA-like domain containing 2
NT5M 5',3'-nucleotidase, mitochondrial
PARP3 poly (ADP-ribose) polymerase family, member 3
PILRA paired immunoglobin-like type 2 receptor alpha
PKNOX2 PBX/knotted 1 homeobox 2
PKP3 plakophilin 3
PRDM14 PR domain containing 14
PRR3 proline rich 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB2A RAB2A, member RAS oncogene family
RAD51B RAD51 paralog B
RBM12B-AS1 RBM12B antisense RNA 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RUNX1 runt-related transcription factor 1
RUNX1-IT1 RUNX1 intronic transcript 1
SAMD4A sterile alpha motif domain containing 4A
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGLEC6 sialic acid binding Ig-like lectin 6
SIRT3 sirtuin 3
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPP1 secreted phosphoprotein 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STK3 serine/threonine kinase 3
SYT1 synaptotagmin I
TBCD tubulin folding cofactor D
TLDC1 TBC/LysM-associated domain containing 1
TMEM8B transmembrane protein 8B
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIB3 tribbles pseudokinase 3
TSPAN8 tetraspanin 8
TTC38 tetratricopeptide repeat domain 38
TUBD1 tubulin, delta 1
UROD uroporphyrinogen decarboxylase
WWOX WW domain containing oxidoreductase
YBX3 Y box binding protein 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZER1 zyg-11 related, cell cycle regulator
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARL14 ADP-ribosylation factor-like 14
ARSJ arylsulfatase family, member J
ASB13 ankyrin repeat and SOCS box containing 13
ATP10D ATPase, class V, type 10D
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAG4 BCL2-associated athanogene 4
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BNC2 basonuclin 2
BTBD2 BTB (POZ) domain containing 2
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
CAMTA2 calmodulin binding transcription activator 2
CCNE2 cyclin E2
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CPVL carboxypeptidase, vitellogenic-like
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DCAF10 DDB1 and CUL4 associated factor 10
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EAF2 ELL associated factor 2
EN2 engrailed homeobox 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM53B family with sequence similarity 53, member B
FZD3 frizzled class receptor 3
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GLDC glycine dehydrogenase (decarboxylating)
GPATCH2 G patch domain containing 2
GPHN gephyrin
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HIRA histone cell cycle regulator
HIRIP3 HIRA interacting protein 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOOK1 hook microtubule-tethering protein 1
HOXA4 homeobox A4
HS1BP3 HCLS1 binding protein 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IMPACT impact RWD domain protein
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0895 KIAA0895
KRT31 keratin 31, type I
LAMB2 laminin, beta 2 (laminin S)
LRP5L low density lipoprotein receptor-related protein 5-like
MNS1 meiosis-specific nuclear structural 1
NDP Norrie disease (pseudoglioma)
NHEJ1 nonhomologous end-joining factor 1
NINJ1 ninjurin 1
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PALMD palmdelphin
PARP16 poly (ADP-ribose) polymerase family, member 16
PECR peroxisomal trans-2-enoyl-CoA reductase
PLSCR4 phospholipid scramblase 4
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRKCD protein kinase C, delta
QTRT1 queuine tRNA-ribosyltransferase 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF121 ring finger protein 121
RNF141 ring finger protein 141
RNF167 ring finger protein 167
RPL23AP32 ribosomal protein L23a pseudogene 32
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SH3BGR SH3 domain binding glutamate-rich protein
SIX1 SIX homeobox 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMAD5 SMAD family member 5
SMYD3 SET and MYND domain containing 3
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
THOP1 thimet oligopeptidase 1
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TNS2 tensin 2
TRAPPC11 trafficking protein particle complex 11
TRDMT1 tRNA aspartic acid methyltransferase 1
TSPAN1 tetraspanin 1
ZBTB48 zinc finger and BTB domain containing 48
ZMYM3 zinc finger, MYM-type 3
ZNF204P zinc finger protein 204, pseudogene
ZNF253 zinc finger protein 253
ZNF254 zinc finger protein 254
ZNF34 zinc finger protein 34
ZNF408 zinc finger protein 408
ZNF426 zinc finger protein 426
ZNF442 zinc finger protein 442
ZNF816 zinc finger protein 816