allantoin-1678 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the allantoin-1678 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACVR1B activin A receptor, type IB
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANGEL2 angel homolog 2 (Drosophila)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARTN artemin
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP9A ATPase, class II, type 9A
BCO1 beta-carotene oxygenase 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C9ORF116 chromosome 9 open reading frame 116
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDC25C cell division cycle 25C
CDK3 cyclin-dependent kinase 3
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COPA coatomer protein complex, subunit alpha
CUL2 cullin 2
CYHR1 cysteine/histidine-rich 1
DCAF4 DDB1 and CUL4 associated factor 4
DLX4 distal-less homeobox 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A eukaryotic translation initiation factor 5A
ENGASE endo-beta-N-acetylglucosaminidase
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
FBXO31 F-box protein 31
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HFE hemochromatosis
HMGA1 high mobility group AT-hook 1
HNMT histamine N-methyltransferase
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
IL22 interleukin 22
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITSN1 intersectin 1 (SH3 domain protein)
KRIT1 KRIT1, ankyrin repeat containing
LIN7A lin-7 homolog A (C. elegans)
LMAN1 lectin, mannose-binding, 1
LOC100287590 uncharacterized LOC100287590
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED1 mediator complex subunit 1
METTL16 methyltransferase like 16
MPPED2 metallophosphoesterase domain containing 2
MYO10 myosin X
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFS1 NFS1 cysteine desulfurase
NLRX1 NLR family member X1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OSMR oncostatin M receptor
PARD6B par-6 family cell polarity regulator beta
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAWR PRKC, apoptosis, WT1, regulator
PEX5 peroxisomal biogenesis factor 5
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLK4 polo-like kinase 4
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PSG9 pregnancy specific beta-1-glycoprotein 9
PSPH phosphoserine phosphatase
PVT1 Pvt1 oncogene (non-protein coding)
RCAN1 regulator of calcineurin 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETD2 SET domain containing 2
SGSM3 small G protein signaling modulator 3
SH2D3A SH2 domain containing 3A
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMAD3 SMAD family member 3
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SORT1 sortilin 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAT1 signal transducer and activator of transcription 1, 91kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TUBGCP3 tubulin, gamma complex associated protein 3
UBOX5 U-box domain containing 5
UBQLN4 ubiquilin 4
VAC14 Vac14 homolog (S. cerevisiae)
VEZT vezatin, adherens junctions transmembrane protein
VIPR2 vasoactive intestinal peptide receptor 2
YY2 YY2 transcription factor
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMYM2 zinc finger, MYM-type 2
ZNF236 zinc finger protein 236
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACYP1 acylphosphatase 1, erythrocyte (common) type
ALPK1 alpha-kinase 1
ARHGAP17 Rho GTPase activating protein 17
ARRB2 arrestin, beta 2
BCOR BCL6 corepressor
C1ORF112 chromosome 1 open reading frame 112
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC88C coiled-coil domain containing 88C
CCNT1 cyclin T1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CIC capicua transcriptional repressor
CLDN15 claudin 15
CORO1A coronin, actin binding protein, 1A
CRYBG3 beta-gamma crystallin domain containing 3
CRYL1 crystallin, lambda 1
CTNNBL1 catenin, beta like 1
CUL9 cullin 9
DDIT3 DNA-damage-inducible transcript 3
DENND4A DENN/MADD domain containing 4A
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFCAB2 EF-hand calcium binding domain 2
ELOVL4 ELOVL fatty acid elongase 4
ERO1L ERO1-like (S. cerevisiae)
ETAA1 Ewing tumor-associated antigen 1
FBXO22 F-box protein 22
FHOD1 formin homology 2 domain containing 1
FLT4 fms-related tyrosine kinase 4
FSD1 fibronectin type III and SPRY domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLS2 glutaminase 2 (liver, mitochondrial)
GMPPA GDP-mannose pyrophosphorylase A
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL1 guanine nucleotide binding protein-like 1
GPR19 G protein-coupled receptor 19
GRB7 growth factor receptor-bound protein 7
GSTM2 glutathione S-transferase mu 2 (muscle)
HINFP histone H4 transcription factor
HMOX1 heme oxygenase 1
HPS6 Hermansky-Pudlak syndrome 6
IFI35 interferon-induced protein 35
IPO8 importin 8
KLHL21 kelch-like family member 21
KLHL36 kelch-like family member 36
LAMB3 laminin, beta 3
LMBR1L limb development membrane protein 1-like
LOC730101 uncharacterized LOC730101
LRP5L low density lipoprotein receptor-related protein 5-like
MAST3 microtubule associated serine/threonine kinase 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MITF microphthalmia-associated transcription factor
MTHFSD methenyltetrahydrofolate synthetase domain containing
NOL12 nucleolar protein 12
NPIPB15 nuclear pore complex interacting protein family, member B15
NRGN neurogranin (protein kinase C substrate, RC3)
PCBP4 poly(rC) binding protein 4
PHACTR4 phosphatase and actin regulator 4
PILRB paired immunoglobin-like type 2 receptor beta
PLA2G3 phospholipase A2, group III
PPAN peter pan homolog (Drosophila)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAMP4 secretory carrier membrane protein 4
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERTAD3 SERTA domain containing 3
SIX1 SIX homeobox 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SND1-IT1 SND1 intronic transcript 1
SOX12 SRY (sex determining region Y)-box 12
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3 stromal antigen 3
STX5 syntaxin 5
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TESC tescalcin
TEX30 testis expressed 30
TLN1 talin 1
TMEM104 transmembrane protein 104
TNS2 tensin 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAF2 TNF receptor-associated factor 2
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
URGCP upregulator of cell proliferation
VASH1 vasohibin 1
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WDR6 WD repeat domain 6
WFS1 Wolfram syndrome 1 (wolframin)
XYLT2 xylosyltransferase II
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF250 zinc finger protein 250
ZNF408 zinc finger protein 408