| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the allantoin-1678 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACVR1B | activin A receptor, type IB |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ARTN | artemin |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATP9A | ATPase, class II, type 9A |
| BCO1 | beta-carotene oxygenase 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C9ORF116 | chromosome 9 open reading frame 116 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CDC25C | cell division cycle 25C |
| CDK3 | cyclin-dependent kinase 3 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| COPA | coatomer protein complex, subunit alpha |
| CUL2 | cullin 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DLX4 | distal-less homeobox 4 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC5 | exocyst complex component 5 |
| FBXO31 | F-box protein 31 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HFE | hemochromatosis |
| HMGA1 | high mobility group AT-hook 1 |
| HNMT | histamine N-methyltransferase |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL11 | interleukin 11 |
| IL22 | interleukin 22 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED1 | mediator complex subunit 1 |
| METTL16 | methyltransferase like 16 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MYO10 | myosin X |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFS1 | NFS1 cysteine desulfurase |
| NLRX1 | NLR family member X1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OSMR | oncostatin M receptor |
| PARD6B | par-6 family cell polarity regulator beta |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PEX5 | peroxisomal biogenesis factor 5 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLK4 | polo-like kinase 4 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PSPH | phosphoserine phosphatase |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RCAN1 | regulator of calcineurin 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SETD2 | SET domain containing 2 |
| SGSM3 | small G protein signaling modulator 3 |
| SH2D3A | SH2 domain containing 3A |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMAD3 | SMAD family member 3 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SORT1 | sortilin 1 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TUBGCP3 | tubulin, gamma complex associated protein 3 |
| UBOX5 | U-box domain containing 5 |
| UBQLN4 | ubiquilin 4 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| YY2 | YY2 transcription factor |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF236 | zinc finger protein 236 |
| ZNF787 | zinc finger protein 787 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ALPK1 | alpha-kinase 1 |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ARRB2 | arrestin, beta 2 |
| BCOR | BCL6 corepressor |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC88C | coiled-coil domain containing 88C |
| CCNT1 | cyclin T1 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CIC | capicua transcriptional repressor |
| CLDN15 | claudin 15 |
| CORO1A | coronin, actin binding protein, 1A |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CRYL1 | crystallin, lambda 1 |
| CTNNBL1 | catenin, beta like 1 |
| CUL9 | cullin 9 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DENND4A | DENN/MADD domain containing 4A |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFCAB2 | EF-hand calcium binding domain 2 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERO1L | ERO1-like (S. cerevisiae) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBXO22 | F-box protein 22 |
| FHOD1 | formin homology 2 domain containing 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR19 | G protein-coupled receptor 19 |
| GRB7 | growth factor receptor-bound protein 7 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HINFP | histone H4 transcription factor |
| HMOX1 | heme oxygenase 1 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFI35 | interferon-induced protein 35 |
| IPO8 | importin 8 |
| KLHL21 | kelch-like family member 21 |
| KLHL36 | kelch-like family member 36 |
| LAMB3 | laminin, beta 3 |
| LMBR1L | limb development membrane protein 1-like |
| LOC730101 | uncharacterized LOC730101 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MITF | microphthalmia-associated transcription factor |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NOL12 | nucleolar protein 12 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PCBP4 | poly(rC) binding protein 4 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLA2G3 | phospholipase A2, group III |
| PPAN | peter pan homolog (Drosophila) |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SERTAD3 | SERTA domain containing 3 |
| SIX1 | SIX homeobox 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAG3 | stromal antigen 3 |
| STX5 | syntaxin 5 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TESC | tescalcin |
| TEX30 | testis expressed 30 |
| TLN1 | talin 1 |
| TMEM104 | transmembrane protein 104 |
| TNS2 | tensin 2 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| URGCP | upregulator of cell proliferation |
| VASH1 | vasohibin 1 |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) |
| WDR6 | WD repeat domain 6 |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| XYLT2 | xylosyltransferase II |
| ZNF205 | zinc finger protein 205 |
| ZNF219 | zinc finger protein 219 |
| ZNF250 | zinc finger protein 250 |
| ZNF408 | zinc finger protein 408 |