allantoin-5052 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the allantoin-5052 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADD2 adducin 2 (beta)
AIM1L absent in melanoma 1-like
AKAP8L A kinase (PRKA) anchor protein 8-like
ARHGAP22 Rho GTPase activating protein 22
ASIC1 acid sensing (proton gated) ion channel 1
ATAT1 alpha tubulin acetyltransferase 1
ATP9A ATPase, class II, type 9A
CCNO cyclin O
CD101 CD101 molecule
CD22 CD22 molecule
CDX1 caudal type homeobox 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHD3 chromodomain helicase DNA binding protein 3
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
DAGLA diacylglycerol lipase, alpha
DFNB31 deafness, autosomal recessive 31
DGCR8 DGCR8 microprocessor complex subunit
DLC1 DLC1 Rho GTPase activating protein
EED embryonic ectoderm development
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFNB1 ephrin-B1
EGFR epidermal growth factor receptor
ELAC2 elaC ribonuclease Z 2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELL2 elongation factor, RNA polymerase II, 2
FAM131B family with sequence similarity 131, member B
FAM174B family with sequence similarity 174, member B
FBXO41 F-box protein 41
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GEMIN7 gem (nuclear organelle) associated protein 7
GIMAP6 GTPase, IMAP family member 6
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA8 gap junction protein, alpha 8, 50kDa
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRB7 growth factor receptor-bound protein 7
HAP1 huntingtin-associated protein 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IL17RB interleukin 17 receptor B
IL36G interleukin 36, gamma
JAK3 Janus kinase 3
KCTD17 potassium channel tetramerization domain containing 17
KLHL35 kelch-like family member 35
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LZTS1 leucine zipper, putative tumor suppressor 1
MASP2 mannan-binding lectin serine peptidase 2
MINK1 misshapen-like kinase 1
MIP major intrinsic protein of lens fiber
MST1 macrophage stimulating 1
MYO1B myosin IB
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOP16 NOP16 nucleolar protein
NR2E3 nuclear receptor subfamily 2, group E, member 3
NTS neurotensin
ONECUT2 one cut homeobox 2
OPRK1 opioid receptor, kappa 1
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PAGE1 P antigen family, member 1 (prostate associated)
PDGFA platelet-derived growth factor alpha polypeptide
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF7 PHD finger protein 7
PHLDB1 pleckstrin homology-like domain, family B, member 1
POM121 POM121 transmembrane nucleoporin
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM1 PR domain containing 1, with ZNF domain
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRX periaxin
PTN pleiotrophin
PTPRH protein tyrosine phosphatase, receptor type, H
PYHIN1 pyrin and HIN domain family, member 1
RGS10 regulator of G-protein signaling 10
RIMS3 regulating synaptic membrane exocytosis 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPL13 ribosomal protein L13
RUNX1 runt-related transcription factor 1
SCAPER S-phase cyclin A-associated protein in the ER
SCLY selenocysteine lyase
SETD1A SET domain containing 1A
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMO smoothened, frizzled class receptor
SPTB spectrin, beta, erythrocytic
STC1 stanniocalcin 1
TEF thyrotrophic embryonic factor
TET3 tet methylcytosine dioxygenase 3
TTLL5 tubulin tyrosine ligase-like family member 5
USP46 ubiquitin specific peptidase 46
WNK1 WNK lysine deficient protein kinase 1
ZFHX2 zinc finger homeobox 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF236 zinc finger protein 236
ZNF609 zinc finger protein 609
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADGRF1 adhesion G protein-coupled receptor F1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANAPC10 anaphase promoting complex subunit 10
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA10 annexin A10
APOL6 apolipoprotein L, 6
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAG4 BCL2-associated athanogene 4
CAPN5 calpain 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CCDC106 coiled-coil domain containing 106
CCDC94 coiled-coil domain containing 94
CD82 CD82 molecule
CFD complement factor D (adipsin)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLIC3 chloride intracellular channel 3
CXCL2 chemokine (C-X-C motif) ligand 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND4A DENN/MADD domain containing 4A
DENND5B DENN/MADD domain containing 5B
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP8 dual specificity phosphatase 8
EML4 echinoderm microtubule associated protein like 4
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXOC5 exocyst complex component 5
FKBP5 FK506 binding protein 5
FRS3 fibroblast growth factor receptor substrate 3
GABARAPL1 GABA(A) receptor-associated protein like 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALT galactose-1-phosphate uridylyltransferase
GJC1 gap junction protein, gamma 1, 45kDa
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GREM1 gremlin 1, DAN family BMP antagonist
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2I general transcription factor IIi
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H3A histone cluster 1, H3a
HIST1H4C histone cluster 1, H4c
HOXA4 homeobox A4
HOXC8 homeobox C8
HP1BP3 heterochromatin protein 1, binding protein 3
IFT81 intraflagellar transport 81
IPO8 importin 8
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LATS1 large tumor suppressor kinase 1
LMAN1 lectin, mannose-binding, 1
LMO7 LIM domain 7
LOC100127972 uncharacterized LOC100127972
LOC100286895 cell division cycle 27 homolog pseudogene
LOC730101 uncharacterized LOC730101
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LYRM2 LYR motif containing 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MT1M metallothionein 1M
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NBEAL2 neurobeachin-like 2
NCKAP1 NCK-associated protein 1
OCLN occludin
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSBP2 oxysterol binding protein 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRKCE protein kinase C, epsilon
PWAR5 Prader Willi/Angelman region RNA 5
QSER1 glutamine and serine rich 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC46A3 solute carrier family 46, member 3
SLITRK5 SLIT and NTRK-like family, member 5
SMA4 glucuronidase, beta pseudogene
SOBP sine oculis binding protein homolog (Drosophila)
SOD3 superoxide dismutase 3, extracellular
SPATA2L spermatogenesis associated 2-like
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM254 transmembrane protein 254
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
ZFHX3 zinc finger homeobox 3
ZFP30 ZFP30 zinc finger protein
ZNF254 zinc finger protein 254
ZNF37BP zinc finger protein 37B, pseudogene
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76
ZNF816 zinc finger protein 816