allantoin-5471 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the allantoin-5471 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AAGAB alpha- and gamma-adaptin binding protein
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACPP acid phosphatase, prostate
ADCY6 adenylate cyclase 6
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALOXE3 arachidonate lipoxygenase 3
ANKLE2 ankyrin repeat and LEM domain containing 2
ART1 ADP-ribosyltransferase 1
BCL2L1 BCL2-like 1
BMP1 bone morphogenetic protein 1
BTBD7 BTB (POZ) domain containing 7
C11ORF16 chromosome 11 open reading frame 16
C7ORF26 chromosome 7 open reading frame 26
CCDC121 coiled-coil domain containing 121
CCDC93 coiled-coil domain containing 93
CD47 CD47 molecule
CD58 CD58 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDY1 chromodomain protein, Y-linked, 1
CLTA clathrin, light chain A
CNTN1 contactin 1
CNTNAP2 contactin associated protein-like 2
CRTC1 CREB regulated transcription coactivator 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
ETNK2 ethanolamine kinase 2
FOXF1 forkhead box F1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA8A golgin A8 family, member A
GPR39 G protein-coupled receptor 39
GRM6 glutamate receptor, metabotropic 6
GSAP gamma-secretase activating protein
H2AFY H2A histone family, member Y
HAO2 hydroxyacid oxidase 2 (long chain)
HLA-G major histocompatibility complex, class I, G
HP1BP3 heterochromatin protein 1, binding protein 3
HR hair growth associated
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFNA14 interferon, alpha 14
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ITK IL2-inducible T-cell kinase
JAG1 jagged 1
JAKMIP2 janus kinase and microtubule interacting protein 2
JPH3 junctophilin 3
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KRT17 keratin 17, type I
LIMCH1 LIM and calponin homology domains 1
LMF2 lipase maturation factor 2
LRRC15 leucine rich repeat containing 15
LUZP1 leucine zipper protein 1
MAP2K7 mitogen-activated protein kinase kinase 7
MED20 mediator complex subunit 20
MFGE8 milk fat globule-EGF factor 8 protein
MON2 MON2 homolog (S. cerevisiae)
MVK mevalonate kinase
MXRA8 matrix-remodelling associated 8
MYOF myoferlin
NCAPH2 non-SMC condensin II complex, subunit H2
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OSMR oncostatin M receptor
PCDHGA10 protocadherin gamma subfamily A, 10
PDZD2 PDZ domain containing 2
PEX11A peroxisomal biogenesis factor 11 alpha
PEX16 peroxisomal biogenesis factor 16
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRF1 perforin 1 (pore forming protein)
PRLR prolactin receptor
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAB11B RAB11B, member RAS oncogene family
RAD51 RAD51 recombinase
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SALL1 spalt-like transcription factor 1
SCRN3 secernin 3
SENP5 SUMO1/sentrin specific peptidase 5
SIX3 SIX homeobox 3
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPHK2 sphingosine kinase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STMN4 stathmin-like 4
SYN2 synapsin II
TAS2R9 taste receptor, type 2, member 9
TCF25 transcription factor 25 (basic helix-loop-helix)
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UCN urocortin
VAV2 vav 2 guanine nucleotide exchange factor
WBP5 WW domain binding protein 5
WNT6 wingless-type MMTV integration site family, member 6
ZNF280A zinc finger protein 280A
ZNF324 zinc finger protein 324
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AHDC1 AT hook, DNA binding motif, containing 1
ALDOC aldolase C, fructose-bisphosphate
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARSB arylsulfatase B
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BBC3 BCL2 binding component 3
BBS1 Bardet-Biedl syndrome 1
BCOR BCL6 corepressor
C10ORF88 chromosome 10 open reading frame 88
C1ORF35 chromosome 1 open reading frame 35
C5ORF45 chromosome 5 open reading frame 45
CDK9 cyclin-dependent kinase 9
CIR1 corepressor interacting with RBPJ, 1
CLCN2 chloride channel, voltage-sensitive 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ENO2 enolase 2 (gamma, neuronal)
EVL Enah/Vasp-like
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FBRS fibrosin
FBXO31 F-box protein 31
FKBP14 FK506 binding protein 14, 22 kDa
GADD45G growth arrest and DNA-damage-inducible, gamma
HOXC10 homeobox C10
IFI6 interferon, alpha-inducible protein 6
IFT22 intraflagellar transport 22
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
IL2 interleukin 2
INF2 inverted formin, FH2 and WH2 domain containing
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
IRF6 interferon regulatory factor 6
IRF9 interferon regulatory factor 9
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL26 kelch-like family member 26
LOC730101 uncharacterized LOC730101
LRP5 low density lipoprotein receptor-related protein 5
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCOLN3 mucolipin 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
MYO1F myosin IF
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
OXTR oxytocin receptor
PAQR6 progestin and adipoQ receptor family member VI
PARP12 poly (ADP-ribose) polymerase family, member 12
PC pyruvate carboxylase
PEX12 peroxisomal biogenesis factor 12
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
POMZP3 POM121 and ZP3 fusion
PYCRL pyrroline-5-carboxylate reductase-like
QPCT glutaminyl-peptide cyclotransferase
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS19 regulator of G-protein signaling 19
RNF122 ring finger protein 122
RNF25 ring finger protein 25
RNH1 ribonuclease/angiogenin inhibitor 1
SCAMP4 secretory carrier membrane protein 4
SH2D4A SH2 domain containing 4A
SHPK sedoheptulokinase
SIK1 salt-inducible kinase 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SPHK1 sphingosine kinase 1
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3 stromal antigen 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBX19 T-box 19
TCTA T-cell leukemia translocation altered
TM6SF1 transmembrane 6 superfamily member 1
TMEM183A transmembrane protein 183A
TNRC6B trinucleotide repeat containing 6B
TOLLIP toll interacting protein
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
WDR4 WD repeat domain 4
WDR60 WD repeat domain 60
ZNF250 zinc finger protein 250
ZNF34 zinc finger protein 34
ZNF354A zinc finger protein 354A
ZNF430 zinc finger protein 430
ZNF639 zinc finger protein 639