alpha-actinin binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats. (Gene Ontology, GO_0051393)
External Link http://amigo.geneontology.org/amigo/term/GO:0051393
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Genes

22 genes performing the alpha-actinin binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LDB3 LIM domain binding 3
LRRC10 leucine rich repeat containing 10
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MYOT myotilin
MYPN myopalladin
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRAP nebulin-related anchoring protein
PALLD palladin, cytoskeletal associated protein
PDLIM2 PDZ and LIM domain 2 (mystique)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKD2L1 polycystic kidney disease 2-like 1
PPARG peroxisome proliferator-activated receptor gamma
RARA retinoic acid receptor, alpha
SYNPO2 synaptopodin 2
TTN titin
XIRP2 xin actin binding repeat containing 2
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