alpha-actinin binding Gene Set
Dataset
GO Molecular Function Annotations 2025
Category
structural or functional annotations
Type
molecular function
Description
Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats. (Gene Ontology , GO_0051393 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0051393
Similar Terms
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Genes
24 genes performing the alpha-actinin binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.
Symbol
Name
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
CNKSR3
CNKSR family member 3
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
KCNA5
potassium channel, voltage gated shaker related subfamily A, member 5
KCNN2
potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LDB3
LIM domain binding 3
MYOT
myotilin
MYPN
myopalladin
NOL6
nucleolar protein 6 (RNA-associated)
PALLD
palladin, cytoskeletal associated protein
PDLIM1
PDZ and LIM domain 1
PDLIM2
PDZ and LIM domain 2 (mystique)
PDLIM3
PDZ and LIM domain 3
PDLIM4
PDZ and LIM domain 4
PDLIM5
PDZ and LIM domain 5
PDLIM7
PDZ and LIM domain 7 (enigma)
PKD2L1
polycystic kidney disease 2-like 1
PPARG
peroxisome proliferator-activated receptor gamma
PRICKLE4
prickle homolog 4 (Drosophila)
PRKD2
protein kinase D2
RARA
retinoic acid receptor, alpha
SYNPO2
synaptopodin 2
TTR
transthyretin
