alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. (Gene Ontology, GO_0032281)
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27 proteins localized to the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CACNG7 calcium channel, voltage-dependent, gamma subunit 7 0.663342
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.237908
CNIH3 cornichon family AMPA receptor auxiliary protein 3 0.237908
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.237908
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 0.237908
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 0.237908
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.237908
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.237908
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 0.237908
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 0.237908
CNIH2 cornichon family AMPA receptor auxiliary protein 2 0.237908
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.237908
DLG4 discs, large homolog 4 (Drosophila) 0.098109
ABHD12 abhydrolase domain containing 12 0.03318
ABHD6 abhydrolase domain containing 6 0.03318
DLG3 discs, large homolog 3 (Drosophila) 0.03318
NRN1 neuritin 1 0.03318
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.03318
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.03318
CPT1C carnitine palmitoyltransferase 1C 0.03318
VWC2 von Willebrand factor C domain containing 2 0.03318
OLFM1 olfactomedin 1 0.03318
OLFM2 olfactomedin 2 0.03318
OLFM3 olfactomedin 3 0.03318
PORCN porcupine homolog (Drosophila) 0.03318
SHISA6 shisa family member 6 0.03318
VWC2L von Willebrand factor C domain containing protein 2-like 0.03318