alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. (Gene Ontology, GO_0032281)
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10 proteins co-occuring with the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
GRIA1 glutamate receptor, ionotropic, AMPA 1 2.28299
GRIA4 glutamate receptor, ionotropic, AMPA 4 2.13113
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 1.28569
GRIK1 glutamate receptor, ionotropic, kainate 1 1.0109
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.881477
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.638861
GRIP1 glutamate receptor interacting protein 1 0.500664
CA4 carbonic anhydrase IV 0.491752
GRM1 glutamate receptor, metabotropic 1 0.29586
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.2708