alpha-ergocryptine-3434 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the alpha-ergocryptine-3434 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACVR1B activin A receptor, type IB
AGRN agrin
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APLP2 amyloid beta (A4) precursor-like protein 2
APOD apolipoprotein D
ARHGAP1 Rho GTPase activating protein 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BBC3 BCL2 binding component 3
BTBD7 BTB (POZ) domain containing 7
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
COL5A1 collagen, type V, alpha 1
CSF1R colony stimulating factor 1 receptor
CUL7 cullin 7
CYHR1 cysteine/histidine-rich 1
DCAF15 DDB1 and CUL4 associated factor 15
DIXDC1 DIX domain containing 1
EML2 echinoderm microtubule associated protein like 2
FHL1 four and a half LIM domains 1
FMO5 flavin containing monooxygenase 5
GAMT guanidinoacetate N-methyltransferase
GFI1 growth factor independent 1 transcription repressor
GK glycerol kinase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GP1BB glycoprotein Ib (platelet), beta polypeptide
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSN gelsolin
HOXC4 homeobox C4
HSPA1L heat shock 70kDa protein 1-like
HYI hydroxypyruvate isomerase (putative)
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGL immunoglobulin lambda locus
INHBE inhibin, beta E
IQSEC2 IQ motif and Sec7 domain 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1109 KIAA1109
KIF22 kinesin family member 22
KLK5 kallikrein-related peptidase 5
LMAN1 lectin, mannose-binding, 1
LMNB1 lamin B1
LYST lysosomal trafficking regulator
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK8 mitogen-activated protein kinase 8
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAT6 N-acetyltransferase 6 (GCN5-related)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OASL 2'-5'-oligoadenylate synthetase-like
ORC5 origin recognition complex, subunit 5
PARD6B par-6 family cell polarity regulator beta
PCM1 pericentriolar material 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PICALM phosphatidylinositol binding clathrin assembly protein
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PTGES prostaglandin E synthase
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RB1 retinoblastoma 1
RCAN1 regulator of calcineurin 1
RNF122 ring finger protein 122
SCAMP1 secretory carrier membrane protein 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SKAP2 src kinase associated phosphoprotein 2
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SRCAP Snf2-related CREBBP activator protein
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAB1 stabilin 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STC1 stanniocalcin 1
TFDP3 transcription factor Dp family, member 3
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
TXNIP thioredoxin interacting protein
UBOX5 U-box domain containing 5
UST uronyl-2-sulfotransferase
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VIPR2 vasoactive intestinal peptide receptor 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF227 zinc finger protein 227
ZNF253 zinc finger protein 253
ZNF423 zinc finger protein 423
ZNF43 zinc finger protein 43
ZNF639 zinc finger protein 639
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD28 ankyrin repeat domain 28
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL15 ADP-ribosylation factor-like 15
ATAD2B ATPase family, AAA domain containing 2B
ATG2A autophagy related 2A
AXIN1 axin 1
BAG4 BCL2-associated athanogene 4
BAK1 BCL2-antagonist/killer 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
C10ORF88 chromosome 10 open reading frame 88
C16ORF59 chromosome 16 open reading frame 59
C19ORF53 chromosome 19 open reading frame 53
CALML4 calmodulin-like 4
CCDC88C coiled-coil domain containing 88C
CCDC9 coiled-coil domain containing 9
CDK3 cyclin-dependent kinase 3
CHST10 carbohydrate sulfotransferase 10
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIC capicua transcriptional repressor
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CYB5R1 cytochrome b5 reductase 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DVL1 dishevelled segment polarity protein 1
EDC4 enhancer of mRNA decapping 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ESRP2 epithelial splicing regulatory protein 2
EVPL envoplakin
FAM53B family with sequence similarity 53, member B
FAM86C1 family with sequence similarity 86, member C1
FLRT3 fibronectin leucine rich transmembrane protein 3
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMEB1 glucocorticoid modulatory element binding protein 1
GMIP GEM interacting protein
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIRA histone cell cycle regulator
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
INHBB inhibin, beta B
IRF6 interferon regulatory factor 6
JMJD4 jumonji domain containing 4
KLHL36 kelch-like family member 36
LPCAT1 lysophosphatidylcholine acyltransferase 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MGMT O-6-methylguanine-DNA methyltransferase
MNX1 motor neuron and pancreas homeobox 1
MTCH1 mitochondrial carrier 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPT2 palmitoyl-protein thioesterase 2
PRPH peripherin
PTDSS2 phosphatidylserine synthase 2
PYCRL pyrroline-5-carboxylate reductase-like
RBM38 RNA binding motif protein 38
RBM42 RNA binding motif protein 42
REPIN1 replication initiator 1
RHOB ras homolog family member B
RIBC2 RIB43A domain with coiled-coils 2
SAYSD1 SAYSVFN motif domain containing 1
SCAMP4 secretory carrier membrane protein 4
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIRT6 sirtuin 6
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SNAI2 snail family zinc finger 2
SPATA2L spermatogenesis associated 2-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRD5A3 steroid 5 alpha-reductase 3
TBC1D10B TBC1 domain family, member 10B
THBS3 thrombospondin 3
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRIM26 tripartite motif containing 26
TSPYL2 TSPY-like 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBXN6 UBX domain protein 6
USP36 ubiquitin specific peptidase 36
VWA1 von Willebrand factor A domain containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZNF268 zinc finger protein 268
ZNF652 zinc finger protein 652
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZXDC ZXD family zinc finger C