alpha-ergocryptine-4552 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the alpha-ergocryptine-4552 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM20 ADAM metallopeptidase domain 20
AKR1C2 aldo-keto reductase family 1, member C2
ARTN artemin
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
B9D2 B9 protein domain 2
BBC3 BCL2 binding component 3
BTG2 BTG family, member 2
C17ORF53 chromosome 17 open reading frame 53
CARD14 caspase recruitment domain family, member 14
CBX8 chromobox homolog 8
CCDC57 coiled-coil domain containing 57
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCN7 chloride channel, voltage-sensitive 7
COL1A2 collagen, type I, alpha 2
CPA2 carboxypeptidase A2 (pancreatic)
CTNND2 catenin (cadherin-associated protein), delta 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNM2 dynamin 2
DPF1 D4, zinc and double PHD fingers family 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ETV1 ets variant 1
EVI2B ecotropic viral integration site 2B
FBXO22 F-box protein 22
FGF23 fibroblast growth factor 23
FLJ42627 uncharacterized LOC645644
FOXE1 forkhead box E1
FRMPD4 FERM and PDZ domain containing 4
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GIPR gastric inhibitory polypeptide receptor
GK3P glycerol kinase 3 pseudogene
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRK5 G protein-coupled receptor kinase 5
HABP2 hyaluronan binding protein 2
HEMK1 HemK methyltransferase family member 1
HHAT hedgehog acyltransferase
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IFNA17 interferon, alpha 17
IL1RL1 interleukin 1 receptor-like 1
IL2 interleukin 2
IRAK4 interleukin-1 receptor-associated kinase 4
ITGA7 integrin, alpha 7
ITGB8 integrin, beta 8
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNIP2 Kv channel interacting protein 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLRF1 killer cell lectin-like receptor subfamily F, member 1
LECT2 leukocyte cell-derived chemotaxin 2
LOC1720 dihydrofolate reductase pseudogene
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBD2 methyl-CpG binding domain protein 2
MED16 mediator complex subunit 16
MEFV Mediterranean fever
MEGF9 multiple EGF-like-domains 9
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MORN1 MORN repeat containing 1
MR1 major histocompatibility complex, class I-related
MTMR8 myotubularin related protein 8
MUC2 mucin 2, oligomeric mucus/gel-forming
NPAS3 neuronal PAS domain protein 3
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NYNRIN NYN domain and retroviral integrase containing
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PDE4D phosphodiesterase 4D, cAMP-specific
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PQLC2 PQ loop repeat containing 2
PSG3 pregnancy specific beta-1-glycoprotein 3
PTCRA pre T-cell antigen receptor alpha
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRH protein tyrosine phosphatase, receptor type, H
PYY peptide YY
RCAN2 regulator of calcineurin 2
RGS10 regulator of G-protein signaling 10
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SPN sialophorin
SPON1 spondin 1, extracellular matrix protein
TBC1D2 TBC1 domain family, member 2
TEX15 testis expressed 15
TLDC1 TBC/LysM-associated domain containing 1
TLN2 talin 2
TMPRSS11D transmembrane protease, serine 11D
TONSL tonsoku-like, DNA repair protein
TP53I11 tumor protein p53 inducible protein 11
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZNF280B zinc finger protein 280B
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD17B abhydrolase domain containing 17B
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALPK1 alpha-kinase 1
ANXA2P3 annexin A2 pseudogene 3
ASAP1-IT1 ASAP1 intronic transcript 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
C10ORF88 chromosome 10 open reading frame 88
C11ORF95 chromosome 11 open reading frame 95
C22ORF29 chromosome 22 open reading frame 29
C4ORF19 chromosome 4 open reading frame 19
C5ORF42 chromosome 5 open reading frame 42
C5ORF45 chromosome 5 open reading frame 45
CAPN15 calpain 15
CBR4 carbonyl reductase 4
CEMIP cell migration inducing protein, hyaluronan binding
CHST10 carbohydrate sulfotransferase 10
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COG4 component of oligomeric golgi complex 4
CPPED1 calcineurin-like phosphoesterase domain containing 1
DDN dendrin
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
EGR2 early growth response 2
EHF ets homologous factor
EPHX2 epoxide hydrolase 2, cytoplasmic
EVPL envoplakin
FAM86C1 family with sequence similarity 86, member C1
FANCF Fanconi anemia, complementation group F
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXN2 forkhead box N2
GLDC glycine dehydrogenase (decarboxylating)
GPATCH3 G patch domain containing 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HOXC8 homeobox C8
IFI44L interferon-induced protein 44-like
IL4R interleukin 4 receptor
INF2 inverted formin, FH2 and WH2 domain containing
IRF6 interferon regulatory factor 6
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLHL36 kelch-like family member 36
KRT6A keratin 6A, type II
KRT75 keratin 75, type II
LINS lines homolog (Drosophila)
LOC390998 ribosomal protein L10 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
MFSD11 major facilitator superfamily domain containing 11
MLYCD malonyl-CoA decarboxylase
MNX1 motor neuron and pancreas homeobox 1
MOXD1 monooxygenase, DBH-like 1
MTA2 metastasis associated 1 family, member 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
MX1 MX dynamin-like GTPase 1
MXRA8 matrix-remodelling associated 8
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME5 NME/NM23 family member 5
NOL6 nucleolar protein 6 (RNA-associated)
NT5C 5', 3'-nucleotidase, cytosolic
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGPEP1 pyroglutamyl-peptidase I
PLAC8 placenta-specific 8
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLH polymerase (DNA directed), eta
PRR3 proline rich 3
PRSS8 protease, serine, 8
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QTRT1 queuine tRNA-ribosyltransferase 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOB ras homolog family member B
RPS17P5 ribosomal protein S17 pseudogene 5
RUFY2 RUN and FYVE domain containing 2
SCD5 stearoyl-CoA desaturase 5
SEPP1 selenoprotein P, plasma, 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SNORA21 small nucleolar RNA, H/ACA box 21
SOX12 SRY (sex determining region Y)-box 12
SPRYD7 SPRY domain containing 7
ST5 suppression of tumorigenicity 5
STAG3 stromal antigen 3
TBXAS1 thromboxane A synthase 1 (platelet)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
TXNL4B thioredoxin-like 4B
VASH1 vasohibin 1
VWA1 von Willebrand factor A domain containing 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF10 zinc finger protein 10
ZNF37BP zinc finger protein 37B, pseudogene
ZNF623 zinc finger protein 623
ZNF675 zinc finger protein 675