Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the alpha-estradiol-6169 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABLIM1 | actin binding LIM protein 1 |
ACACB | acetyl-CoA carboxylase beta |
ACO2 | aconitase 2, mitochondrial |
ACTA1 | actin, alpha 1, skeletal muscle |
ADAM22 | ADAM metallopeptidase domain 22 |
ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
AHSP | alpha hemoglobin stabilizing protein |
AK5 | adenylate kinase 5 |
ANXA2P3 | annexin A2 pseudogene 3 |
ASIC4 | acid sensing (proton gated) ion channel family member 4 |
BTNL3 | butyrophilin-like 3 |
BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
C17ORF59 | chromosome 17 open reading frame 59 |
CADPS2 | Ca++-dependent secretion activator 2 |
CAMP | cathelicidin antimicrobial peptide |
CASP10 | caspase 10, apoptosis-related cysteine peptidase |
CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
CCDC85B | coiled-coil domain containing 85B |
CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
CFAP70 | cilia and flagella associated protein 70 |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
CLTA | clathrin, light chain A |
CPLX2 | complexin 2 |
CRP | C-reactive protein, pentraxin-related |
CUL7 | cullin 7 |
CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
DSCAM | Down syndrome cell adhesion molecule |
DVL2 | dishevelled segment polarity protein 2 |
EPS8L3 | EPS8-like 3 |
ESR1 | estrogen receptor 1 |
ETV7 | ets variant 7 |
FAM189A1 | family with sequence similarity 189, member A1 |
FBXL18 | F-box and leucine-rich repeat protein 18 |
FBXO31 | F-box protein 31 |
FGFR2 | fibroblast growth factor receptor 2 |
GAP43 | growth associated protein 43 |
GLYAT | glycine-N-acyltransferase |
GPC1 | glypican 1 |
GPM6B | glycoprotein M6B |
GPR153 | G protein-coupled receptor 153 |
GTPBP1 | GTP binding protein 1 |
HFE | hemochromatosis |
HHLA1 | HERV-H LTR-associating 1 |
HIST1H4E | histone cluster 1, H4e |
HNF1B | HNF1 homeobox B |
HOMER2 | homer scaffolding protein 2 |
HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
IGFBP5 | insulin-like growth factor binding protein 5 |
IQSEC1 | IQ motif and Sec7 domain 1 |
ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 |
ITM2A | integral membrane protein 2A |
KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
KIF25 | kinesin family member 25 |
LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
MC5R | melanocortin 5 receptor |
MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
MLXIP | MLX interacting protein |
MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
MRC2 | mannose receptor, C type 2 |
MTMR8 | myotubularin related protein 8 |
MYBPC3 | myosin binding protein C, cardiac |
MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
NIPAL2 | NIPA-like domain containing 2 |
NPTX1 | neuronal pentraxin I |
NTS | neurotensin |
OLFM1 | olfactomedin 1 |
OSBPL7 | oxysterol binding protein-like 7 |
PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
PCDH17 | protocadherin 17 |
PCDHGB5 | protocadherin gamma subfamily B, 5 |
PCDHGC3 | protocadherin gamma subfamily C, 3 |
PDE4D | phosphodiesterase 4D, cAMP-specific |
PIGR | polymeric immunoglobulin receptor |
PLXNA2 | plexin A2 |
PRB4 | proline-rich protein BstNI subfamily 4 |
PRKY | protein kinase, Y-linked, pseudogene |
PTCRA | pre T-cell antigen receptor alpha |
RAB3D | RAB3D, member RAS oncogene family |
RASAL2 | RAS protein activator like 2 |
RPL10L | ribosomal protein L10-like |
SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
SLC16A4 | solute carrier family 16, member 4 |
SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
SPAG4 | sperm associated antigen 4 |
SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
SSX1 | synovial sarcoma, X breakpoint 1 |
SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
TBCD | tubulin folding cofactor D |
TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
TRPA1 | transient receptor potential cation channel, subfamily A, member 1 |
UBQLN4 | ubiquilin 4 |
USP46 | ubiquitin specific peptidase 46 |
VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
WNT16 | wingless-type MMTV integration site family, member 16 |
ZBED2 | zinc finger, BED-type containing 2 |
ZNF93 | zinc finger protein 93 |
Symbol | Name |
---|---|
ALPK1 | alpha-kinase 1 |
ANO10 | anoctamin 10 |
ARMC6 | armadillo repeat containing 6 |
B3GNT1 | |
BAHD1 | bromo adjacent homology domain containing 1 |
BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
BTBD18 | BTB (POZ) domain containing 18 |
C22ORF46 | chromosome 22 open reading frame 46 |
C8ORF44 | chromosome 8 open reading frame 44 |
CARM1 | coactivator-associated arginine methyltransferase 1 |
CCL4 | chemokine (C-C motif) ligand 4 |
CGRRF1 | cell growth regulator with ring finger domain 1 |
CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
CRYL1 | crystallin, lambda 1 |
CTSV | cathepsin V |
DOK3 | docking protein 3 |
EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
EFHC1 | EF-hand domain (C-terminal) containing 1 |
EXD3 | exonuclease 3'-5' domain containing 3 |
EXOC2 | exocyst complex component 2 |
FAM172A | family with sequence similarity 172, member A |
FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
FOSL1 | FOS-like antigen 1 |
FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
GLCE | glucuronic acid epimerase |
GPATCH2 | G patch domain containing 2 |
GPATCH2L | G patch domain containing 2-like |
GPR35 | G protein-coupled receptor 35 |
HHLA3 | HERV-H LTR-associating 3 |
HIST1H2AJ | histone cluster 1, H2aj |
HLA-DMB | major histocompatibility complex, class II, DM beta |
HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
HOXA1 | homeobox A1 |
IDI2-AS1 | IDI2 antisense RNA 1 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
ITGB7 | integrin, beta 7 |
ITPKC | inositol-trisphosphate 3-kinase C |
KIAA0319L | KIAA0319-like |
KIAA0753 | KIAA0753 |
KIAA1024 | KIAA1024 |
KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
LHFP | lipoma HMGIC fusion partner |
LTC4S | leukotriene C4 synthase |
MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
MON1B | MON1 secretory trafficking family member B |
MTA2 | metastasis associated 1 family, member 2 |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
MYO15A | myosin XVA |
NHEJ1 | nonhomologous end-joining factor 1 |
NPIPB3 | nuclear pore complex interacting protein family, member B3 |
NPM3 | nucleophosmin/nucleoplasmin 3 |
NT5M | 5',3'-nucleotidase, mitochondrial |
PDGFD | platelet derived growth factor D |
PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
PHC1 | polyhomeotic homolog 1 (Drosophila) |
PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
POM121 | POM121 transmembrane nucleoporin |
PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PPT2 | palmitoyl-protein thioesterase 2 |
PTPRS | protein tyrosine phosphatase, receptor type, S |
PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
PYCRL | pyrroline-5-carboxylate reductase-like |
PYGB | phosphorylase, glycogen; brain |
R3HCC1L | R3H domain and coiled-coil containing 1-like |
RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
RPAP1 | RNA polymerase II associated protein 1 |
S1PR4 | sphingosine-1-phosphate receptor 4 |
SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SETD8 | SET domain containing (lysine methyltransferase) 8 |
SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
SMYD5 | SMYD family member 5 |
SPRYD7 | SPRY domain containing 7 |
TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
TCTN1 | tectonic family member 1 |
TGM5 | transglutaminase 5 |
TIMP2 | TIMP metallopeptidase inhibitor 2 |
TPBG | trophoblast glycoprotein |
TPST1 | tyrosylprotein sulfotransferase 1 |
TRIM5 | tripartite motif containing 5 |
TRPS1 | trichorhinophalangeal syndrome I |
TUBA3C | tubulin, alpha 3c |
UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
UNC119 | unc-119 homolog (C. elegans) |
USB1 | U6 snRNA biogenesis 1 |
USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
WDR33 | WD repeat domain 33 |
WDR91 | WD repeat domain 91 |
ZBED1 | zinc finger, BED-type containing 1 |
ZC4H2 | zinc finger, C4H2 domain containing |
ZNF134 | zinc finger protein 134 |
ZNF322P1 | zinc finger protein 322 pseudogene 1 |
ZNF506 | zinc finger protein 506 |
ZNF668 | zinc finger protein 668 |