| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alpha-estradiol-6169 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| ACACB | acetyl-CoA carboxylase beta |
| ACO2 | aconitase 2, mitochondrial |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AHSP | alpha hemoglobin stabilizing protein |
| AK5 | adenylate kinase 5 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| BTNL3 | butyrophilin-like 3 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CAMP | cathelicidin antimicrobial peptide |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC85B | coiled-coil domain containing 85B |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CFAP70 | cilia and flagella associated protein 70 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLTA | clathrin, light chain A |
| CPLX2 | complexin 2 |
| CRP | C-reactive protein, pentraxin-related |
| CUL7 | cullin 7 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DSCAM | Down syndrome cell adhesion molecule |
| DVL2 | dishevelled segment polarity protein 2 |
| EPS8L3 | EPS8-like 3 |
| ESR1 | estrogen receptor 1 |
| ETV7 | ets variant 7 |
| FAM189A1 | family with sequence similarity 189, member A1 |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FBXO31 | F-box protein 31 |
| FGFR2 | fibroblast growth factor receptor 2 |
| GAP43 | growth associated protein 43 |
| GLYAT | glycine-N-acyltransferase |
| GPC1 | glypican 1 |
| GPM6B | glycoprotein M6B |
| GPR153 | G protein-coupled receptor 153 |
| GTPBP1 | GTP binding protein 1 |
| HFE | hemochromatosis |
| HHLA1 | HERV-H LTR-associating 1 |
| HIST1H4E | histone cluster 1, H4e |
| HNF1B | HNF1 homeobox B |
| HOMER2 | homer scaffolding protein 2 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 |
| ITM2A | integral membrane protein 2A |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KIF25 | kinesin family member 25 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
| MC5R | melanocortin 5 receptor |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MLXIP | MLX interacting protein |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MRC2 | mannose receptor, C type 2 |
| MTMR8 | myotubularin related protein 8 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| NIPAL2 | NIPA-like domain containing 2 |
| NPTX1 | neuronal pentraxin I |
| NTS | neurotensin |
| OLFM1 | olfactomedin 1 |
| OSBPL7 | oxysterol binding protein-like 7 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDH17 | protocadherin 17 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCDHGC3 | protocadherin gamma subfamily C, 3 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PIGR | polymeric immunoglobulin receptor |
| PLXNA2 | plexin A2 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRKY | protein kinase, Y-linked, pseudogene |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB3D | RAB3D, member RAS oncogene family |
| RASAL2 | RAS protein activator like 2 |
| RPL10L | ribosomal protein L10-like |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SPAG4 | sperm associated antigen 4 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TBCD | tubulin folding cofactor D |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 |
| UBQLN4 | ubiquilin 4 |
| USP46 | ubiquitin specific peptidase 46 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBED2 | zinc finger, BED-type containing 2 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| ANO10 | anoctamin 10 |
| ARMC6 | armadillo repeat containing 6 |
| B3GNT1 | |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| BTBD18 | BTB (POZ) domain containing 18 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CARM1 | coactivator-associated arginine methyltransferase 1 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CRYL1 | crystallin, lambda 1 |
| CTSV | cathepsin V |
| DOK3 | docking protein 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXOC2 | exocyst complex component 2 |
| FAM172A | family with sequence similarity 172, member A |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOSL1 | FOS-like antigen 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GLCE | glucuronic acid epimerase |
| GPATCH2 | G patch domain containing 2 |
| GPATCH2L | G patch domain containing 2-like |
| GPR35 | G protein-coupled receptor 35 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HOXA1 | homeobox A1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| ITGB7 | integrin, beta 7 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA0319L | KIAA0319-like |
| KIAA0753 | KIAA0753 |
| KIAA1024 | KIAA1024 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LHFP | lipoma HMGIC fusion partner |
| LTC4S | leukotriene C4 synthase |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MON1B | MON1 secretory trafficking family member B |
| MTA2 | metastasis associated 1 family, member 2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO15A | myosin XVA |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PDGFD | platelet derived growth factor D |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POM121 | POM121 transmembrane nucleoporin |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| PYGB | phosphorylase, glycogen; brain |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPAP1 | RNA polymerase II associated protein 1 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SMYD5 | SMYD family member 5 |
| SPRYD7 | SPRY domain containing 7 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN1 | tectonic family member 1 |
| TGM5 | transglutaminase 5 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TPBG | trophoblast glycoprotein |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIM5 | tripartite motif containing 5 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TUBA3C | tubulin, alpha 3c |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| WDR91 | WD repeat domain 91 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZNF134 | zinc finger protein 134 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF506 | zinc finger protein 506 |
| ZNF668 | zinc finger protein 668 |
