Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the alpha-estradiol-6930 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD6 | abhydrolase domain containing 6 |
ADCK2 | aarF domain containing kinase 2 |
AHI1 | Abelson helper integration site 1 |
AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
ANKRD40 | ankyrin repeat domain 40 |
APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
ARNT | aryl hydrocarbon receptor nuclear translocator |
ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
BGN | biglycan |
BLVRA | biliverdin reductase A |
C17ORF80 | chromosome 17 open reading frame 80 |
C2ORF72 | chromosome 2 open reading frame 72 |
CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
CDK13 | cyclin-dependent kinase 13 |
CEP68 | centrosomal protein 68kDa |
CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
COL5A1 | collagen, type V, alpha 1 |
CPT1A | carnitine palmitoyltransferase 1A (liver) |
CRYBG3 | beta-gamma crystallin domain containing 3 |
CRYGC | crystallin, gamma C |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DCAF11 | DDB1 and CUL4 associated factor 11 |
DHODH | dihydroorotate dehydrogenase (quinone) |
DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
DNPEP | aspartyl aminopeptidase |
DVL3 | dishevelled segment polarity protein 3 |
EAF2 | ELL associated factor 2 |
EGR3 | early growth response 3 |
ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
GGT1 | gamma-glutamyltransferase 1 |
GRK6 | G protein-coupled receptor kinase 6 |
GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
HDAC11 | histone deacetylase 11 |
HDAC4 | histone deacetylase 4 |
HFE | hemochromatosis |
HIST1H2AB | histone cluster 1, H2ab |
ICOS | inducible T-cell co-stimulator |
IGLJ3 | immunoglobulin lambda joining 3 |
IL15RA | interleukin 15 receptor, alpha |
KREMEN2 | kringle containing transmembrane protein 2 |
LAMB3 | laminin, beta 3 |
LIME1 | Lck interacting transmembrane adaptor 1 |
LOC100127972 | uncharacterized LOC100127972 |
LOC100129648 | uncharacterized LOC100129648 |
LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
LRRC23 | leucine rich repeat containing 23 |
MAOA | monoamine oxidase A |
MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
MATK | megakaryocyte-associated tyrosine kinase |
MEIS1 | Meis homeobox 1 |
MFN2 | mitofusin 2 |
MKL1 | megakaryoblastic leukemia (translocation) 1 |
MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
MPZL1 | myelin protein zero-like 1 |
MRPS14 | mitochondrial ribosomal protein S14 |
MTCP1 | mature T-cell proliferation 1 |
MTRF1L | mitochondrial translational release factor 1-like |
MYBPC2 | myosin binding protein C, fast type |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
NKX3-2 | NK3 homeobox 2 |
OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
ORAI2 | ORAI calcium release-activated calcium modulator 2 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
RAB2A | RAB2A, member RAS oncogene family |
RP2 | retinitis pigmentosa 2 (X-linked recessive) |
RTEL1 | regulator of telomere elongation helicase 1 |
SIN3B | SIN3 transcription regulator family member B |
SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
SIX3 | SIX homeobox 3 |
SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
SLN | sarcolipin |
SMG7-AS1 | SMG7 antisense RNA 1 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
SRD5A3 | steroid 5 alpha-reductase 3 |
TAT | tyrosine aminotransferase |
TDRD1 | tudor domain containing 1 |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
TLE4 | transducin-like enhancer of split 4 |
TMEM63A | transmembrane protein 63A |
TWF1 | twinfilin actin binding protein 1 |
UNC93B1 | unc-93 homolog B1 (C. elegans) |
USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
VLDLR | very low density lipoprotein receptor |
WDR62 | WD repeat domain 62 |
XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
YLPM1 | YLP motif containing 1 |
ZNF407 | zinc finger protein 407 |
ZSCAN26 | zinc finger and SCAN domain containing 26 |
Symbol | Name |
---|---|
ADRA2C | adrenoceptor alpha 2C |
AEN | apoptosis enhancing nuclease |
AGBL5 | ATP/GTP binding protein-like 5 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
BBC3 | BCL2 binding component 3 |
BCOR | BCL6 corepressor |
BPGM | 2,3-bisphosphoglycerate mutase |
C10ORF88 | chromosome 10 open reading frame 88 |
C16ORF59 | chromosome 16 open reading frame 59 |
C17ORF75 | chromosome 17 open reading frame 75 |
CAPN15 | calpain 15 |
CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
CGREF1 | cell growth regulator with EF-hand domain 1 |
CHKB | choline kinase beta |
CLK1 | CDC-like kinase 1 |
CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
COCH | cochlin |
CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
EVPL | envoplakin |
FAM188A | family with sequence similarity 188, member A |
FDXR | ferredoxin reductase |
FGD6 | FYVE, RhoGEF and PH domain containing 6 |
FOXO1 | forkhead box O1 |
GLCE | glucuronic acid epimerase |
GPR87 | G protein-coupled receptor 87 |
HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 |
HIST1H2AG | histone cluster 1, H2ag |
HOXC13 | homeobox C13 |
HSPA4L | heat shock 70kDa protein 4-like |
ICK | intestinal cell (MAK-like) kinase |
IFT22 | intraflagellar transport 22 |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
JMJD1C | jumonji domain containing 1C |
KATNBL1 | katanin p80 subunit B-like 1 |
KIAA0894 | KIAA0894 protein |
KIAA0922 | KIAA0922 |
KLHL2 | kelch-like family member 2 |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LY6D | lymphocyte antigen 6 complex, locus D |
MAGEF1 | melanoma antigen family F1 |
MAST3 | microtubule associated serine/threonine kinase 3 |
METTL16 | methyltransferase like 16 |
MORC3 | MORC family CW-type zinc finger 3 |
NBAS | neuroblastoma amplified sequence |
NHEJ1 | nonhomologous end-joining factor 1 |
P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
PACS1 | phosphofurin acidic cluster sorting protein 1 |
PARP16 | poly (ADP-ribose) polymerase family, member 16 |
PCBP4 | poly(rC) binding protein 4 |
PDZRN3 | PDZ domain containing ring finger 3 |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PODXL2 | podocalyxin-like 2 |
POTEKP | POTE ankyrin domain family, member K, pseudogene |
PRKX | protein kinase, X-linked |
PRODH | proline dehydrogenase (oxidase) 1 |
PRR3 | proline rich 3 |
PTDSS2 | phosphatidylserine synthase 2 |
PTPRU | protein tyrosine phosphatase, receptor type, U |
PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
RAD54L2 | RAD54-like 2 (S. cerevisiae) |
RANGRF | RAN guanine nucleotide release factor |
RBM41 | RNA binding motif protein 41 |
REPS2 | RALBP1 associated Eps domain containing 2 |
RNF31 | ring finger protein 31 |
RPH3AL | rabphilin 3A-like (without C2 domains) |
SALL2 | spalt-like transcription factor 2 |
SCAMP3 | secretory carrier membrane protein 3 |
SLC12A9 | solute carrier family 12, member 9 |
SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
SLC35F6 | solute carrier family 35, member F6 |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
STAG3 | stromal antigen 3 |
SUN2 | Sad1 and UNC84 domain containing 2 |
TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
TMOD3 | tropomodulin 3 (ubiquitous) |
TSSC4 | tumor suppressing subtransferable candidate 4 |
USP36 | ubiquitin specific peptidase 36 |
VWA1 | von Willebrand factor A domain containing 1 |
WDR44 | WD repeat domain 44 |
ZBTB39 | zinc finger and BTB domain containing 39 |
ZC3H12A | zinc finger CCCH-type containing 12A |
ZDHHC24 | zinc finger, DHHC-type containing 24 |
ZMAT5 | zinc finger, matrin-type 5 |
ZNF180 | zinc finger protein 180 |
ZNF184 | zinc finger protein 184 |
ZNF205 | zinc finger protein 205 |
ZNF219 | zinc finger protein 219 |
ZNF268 | zinc finger protein 268 |
ZNF654 | zinc finger protein 654 |
ZNF675 | zinc finger protein 675 |
ZNF767P | zinc finger family member 767, pseudogene |
ZNF778 | zinc finger protein 778 |
ZNF816 | zinc finger protein 816 |