| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the alpha-estradiol-6930 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ADCK2 | aarF domain containing kinase 2 |
| AHI1 | Abelson helper integration site 1 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ANKRD40 | ankyrin repeat domain 40 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BGN | biglycan |
| BLVRA | biliverdin reductase A |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CDK13 | cyclin-dependent kinase 13 |
| CEP68 | centrosomal protein 68kDa |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COL5A1 | collagen, type V, alpha 1 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CRYGC | crystallin, gamma C |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| DNPEP | aspartyl aminopeptidase |
| DVL3 | dishevelled segment polarity protein 3 |
| EAF2 | ELL associated factor 2 |
| EGR3 | early growth response 3 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| GGT1 | gamma-glutamyltransferase 1 |
| GRK6 | G protein-coupled receptor kinase 6 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HDAC11 | histone deacetylase 11 |
| HDAC4 | histone deacetylase 4 |
| HFE | hemochromatosis |
| HIST1H2AB | histone cluster 1, H2ab |
| ICOS | inducible T-cell co-stimulator |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL15RA | interleukin 15 receptor, alpha |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMB3 | laminin, beta 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC100127972 | uncharacterized LOC100127972 |
| LOC100129648 | uncharacterized LOC100129648 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC23 | leucine rich repeat containing 23 |
| MAOA | monoamine oxidase A |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MEIS1 | Meis homeobox 1 |
| MFN2 | mitofusin 2 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MPZL1 | myelin protein zero-like 1 |
| MRPS14 | mitochondrial ribosomal protein S14 |
| MTCP1 | mature T-cell proliferation 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYBPC2 | myosin binding protein C, fast type |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NKX3-2 | NK3 homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| RAB2A | RAB2A, member RAS oncogene family |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SIN3B | SIN3 transcription regulator family member B |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SIX3 | SIX homeobox 3 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLN | sarcolipin |
| SMG7-AS1 | SMG7 antisense RNA 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TAT | tyrosine aminotransferase |
| TDRD1 | tudor domain containing 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM63A | transmembrane protein 63A |
| TWF1 | twinfilin actin binding protein 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VLDLR | very low density lipoprotein receptor |
| WDR62 | WD repeat domain 62 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| YLPM1 | YLP motif containing 1 |
| ZNF407 | zinc finger protein 407 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ADRA2C | adrenoceptor alpha 2C |
| AEN | apoptosis enhancing nuclease |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| BBC3 | BCL2 binding component 3 |
| BCOR | BCL6 corepressor |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| CAPN15 | calpain 15 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHKB | choline kinase beta |
| CLK1 | CDC-like kinase 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COCH | cochlin |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EVPL | envoplakin |
| FAM188A | family with sequence similarity 188, member A |
| FDXR | ferredoxin reductase |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FOXO1 | forkhead box O1 |
| GLCE | glucuronic acid epimerase |
| GPR87 | G protein-coupled receptor 87 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 |
| HIST1H2AG | histone cluster 1, H2ag |
| HOXC13 | homeobox C13 |
| HSPA4L | heat shock 70kDa protein 4-like |
| ICK | intestinal cell (MAK-like) kinase |
| IFT22 | intraflagellar transport 22 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JMJD1C | jumonji domain containing 1C |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0894 | KIAA0894 protein |
| KIAA0922 | KIAA0922 |
| KLHL2 | kelch-like family member 2 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGEF1 | melanoma antigen family F1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL16 | methyltransferase like 16 |
| MORC3 | MORC family CW-type zinc finger 3 |
| NBAS | neuroblastoma amplified sequence |
| NHEJ1 | nonhomologous end-joining factor 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCBP4 | poly(rC) binding protein 4 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PODXL2 | podocalyxin-like 2 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRKX | protein kinase, X-linked |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRR3 | proline rich 3 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RANGRF | RAN guanine nucleotide release factor |
| RBM41 | RNA binding motif protein 41 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RNF31 | ring finger protein 31 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SALL2 | spalt-like transcription factor 2 |
| SCAMP3 | secretory carrier membrane protein 3 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STAG3 | stromal antigen 3 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| USP36 | ubiquitin specific peptidase 36 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR44 | WD repeat domain 44 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF180 | zinc finger protein 180 |
| ZNF184 | zinc finger protein 184 |
| ZNF205 | zinc finger protein 205 |
| ZNF219 | zinc finger protein 219 |
| ZNF268 | zinc finger protein 268 |
| ZNF654 | zinc finger protein 654 |
| ZNF675 | zinc finger protein 675 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF778 | zinc finger protein 778 |
| ZNF816 | zinc finger protein 816 |
