| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alpha-estradiol-6970 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD17B | abhydrolase domain containing 17B |
| ADRA1D | adrenoceptor alpha 1D |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APOC1 | apolipoprotein C-I |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| AURKA | aurora kinase A |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
| BCL2 | B-cell CLL/lymphoma 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CA9 | carbonic anhydrase IX |
| CARD9 | caspase recruitment domain family, member 9 |
| CD47 | CD47 molecule |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLDN17 | claudin 17 |
| CLU | clusterin |
| CRISP2 | cysteine-rich secretory protein 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DAPK2 | death-associated protein kinase 2 |
| DBN1 | drebrin 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EDA | ectodysplasin A |
| EGFL7 | EGF-like-domain, multiple 7 |
| EGR3 | early growth response 3 |
| EPOR | erythropoietin receptor |
| ESR1 | estrogen receptor 1 |
| ETV6 | ets variant 6 |
| FAM131A | family with sequence similarity 131, member A |
| FGL1 | fibrinogen-like 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| GK | glycerol kinase |
| GLP1R | glucagon-like peptide 1 receptor |
| GLS | glutaminase |
| GM2A | GM2 ganglioside activator |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HCFC1 | host cell factor C1 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IDS | iduronate 2-sulfatase |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL11 | interleukin 11 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITM2C | integral membrane protein 2C |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KLHL22 | kelch-like family member 22 |
| KRT19P2 | keratin 19 pseudogene 2 |
| KRT24 | keratin 24, type I |
| LMBR1L | limb development membrane protein 1-like |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAPT | microtubule-associated protein tau |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MED12 | mediator complex subunit 12 |
| MYO10 | myosin X |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
| PGBD5 | piggyBac transposable element derived 5 |
| PHF20 | PHD finger protein 20 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRSS16 | protease, serine, 16 (thymus) |
| PTRF | polymerase I and transcript release factor |
| RBM12 | RNA binding motif protein 12 |
| RIN1 | Ras and Rab interactor 1 |
| RS1 | retinoschisin 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| S100A7 | S100 calcium binding protein A7 |
| SBF1 | SET binding factor 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SORT1 | sortilin 1 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| ST7 | suppression of tumorigenicity 7 |
| TGM2 | transglutaminase 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TPM1 | tropomyosin 1 (alpha) |
| TTC28 | tetratricopeptide repeat domain 28 |
| TUBA3D | tubulin, alpha 3d |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| VEGFA | vascular endothelial growth factor A |
| WDR76 | WD repeat domain 76 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| XK | X-linked Kx blood group |
| ZNF362 | zinc finger protein 362 |
| ZNF473 | zinc finger protein 473 |
| ZNF609 | zinc finger protein 609 |
| ZNF711 | zinc finger protein 711 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACVR2B | activin A receptor, type IIB |
| ADCK3 | aarF domain containing kinase 3 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| AOX1 | aldehyde oxidase 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| C5 | complement component 5 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCDC6 | coiled-coil domain containing 6 |
| CCNT1 | cyclin T1 |
| CENPJ | centromere protein J |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| CORO1A | coronin, actin binding protein, 1A |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CSTA | cystatin A (stefin A) |
| CTC1 | CTS telomere maintenance complex component 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EFNA1 | ephrin-A1 |
| EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EVPL | envoplakin |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXO31 | F-box protein 31 |
| FMO4 | flavin containing monooxygenase 4 |
| FOXK2 | forkhead box K2 |
| GLCE | glucuronic acid epimerase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HAUS2 | HAUS augmin-like complex, subunit 2 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H2AM | histone cluster 1, H2am |
| HOXC13 | homeobox C13 |
| IFT81 | intraflagellar transport 81 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| JADE3 | jade family PHD finger 3 |
| KAT2B | K(lysine) acetyltransferase 2B |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAPK12 | mitogen-activated protein kinase 12 |
| METTL21B | methyltransferase like 21B |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO1E | myosin IE |
| NES | nestin |
| NOTCH1 | notch 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PCTP | phosphatidylcholine transfer protein |
| PGP | phosphoglycolate phosphatase |
| RFX7 | regulatory factor X, 7 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| S100A4 | S100 calcium binding protein A4 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH2B3 | SH2B adaptor protein 3 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNIP1 | Smad nuclear interacting protein 1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SYNGR3 | synaptogyrin 3 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TCTA | T-cell leukemia translocation altered |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UNC119 | unc-119 homolog (C. elegans) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR60 | WD repeat domain 60 |
| YEATS2 | YEATS domain containing 2 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF253 | zinc finger protein 253 |
| ZNF282 | zinc finger protein 282 |
| ZNF432 | zinc finger protein 432 |
| ZNF668 | zinc finger protein 668 |
