alpha-estradiol-762 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


197 genes differentially expressed following the alpha-estradiol-762 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACYP1 acylphosphatase 1, erythrocyte (common) type
AK2 adenylate kinase 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASIC1 acid sensing (proton gated) ion channel 1
B3GAT3 beta-1,3-glucuronyltransferase 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCAS4 breast carcinoma amplified sequence 4
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CADM3 cell adhesion molecule 3
CAPN10 calpain 10
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC25 coiled-coil domain containing 25
CCPG1 cell cycle progression 1
CDT1 chromatin licensing and DNA replication factor 1
CFLAR CASP8 and FADD-like apoptosis regulator
CNTD2 cyclin N-terminal domain containing 2
COPE coatomer protein complex, subunit epsilon
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CPOX coproporphyrinogen oxidase
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTNS cystinosin, lysosomal cystine transporter
CTRC chymotrypsin C (caldecrin)
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DGCR2 DiGeorge syndrome critical region gene 2
DOCK10 dedicator of cytokinesis 10
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ELP6 elongator acetyltransferase complex subunit 6
FAM63A family with sequence similarity 63, member A
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GAS8 growth arrest-specific 8
GCLC glutamate-cysteine ligase, catalytic subunit
GLG1 golgi glycoprotein 1
GPR137 G protein-coupled receptor 137
HNF1B HNF1 homeobox B
HOXB6 homeobox B6
ITSN2 intersectin 2
JAM3 junctional adhesion molecule 3
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KLHL18 kelch-like family member 18
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LGALS8 lectin, galactoside-binding, soluble, 8
LOC729164 hCG1732469
LPAR2 lysophosphatidic acid receptor 2
MAPK12 mitogen-activated protein kinase 12
MBNL2 muscleblind-like splicing regulator 2
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MRC2 mannose receptor, C type 2
MRPL12 mitochondrial ribosomal protein L12
MTO1 mitochondrial tRNA translation optimization 1
MYL10 myosin, light chain 10, regulatory
MZF1 myeloid zinc finger 1
NNT nicotinamide nucleotide transhydrogenase
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NVL nuclear VCP-like
ORAI2 ORAI calcium release-activated calcium modulator 2
PCOLCE procollagen C-endopeptidase enhancer
PDS5A PDS5 cohesin associated factor A
PGRMC2 progesterone receptor membrane component 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGR polymeric immunoglobulin receptor
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRELP proline/arginine-rich end leucine-rich repeat protein
RAB31 RAB31, member RAS oncogene family
RARG retinoic acid receptor, gamma
RBFA ribosome binding factor A (putative)
RPS2 ribosomal protein S2
SEC24A SEC24 family member A
SIAH1 siah E3 ubiquitin protein ligase 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOCS6 suppressor of cytokine signaling 6
SPN sialophorin
STAT1 signal transducer and activator of transcription 1, 91kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAOK2 TAO kinase 2
TEX13B testis expressed 13B
TMPRSS5 transmembrane protease, serine 5
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC10 trafficking protein particle complex 10
USP24 ubiquitin specific peptidase 24
VRK2 vaccinia related kinase 2
VSIG10 V-set and immunoglobulin domain containing 10
ZC3H14 zinc finger CCCH-type containing 14
ZC3H7B zinc finger CCCH-type containing 7B
ZFR zinc finger RNA binding protein
ZNF652 zinc finger protein 652
ZNF79 zinc finger protein 79
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALPK1 alpha-kinase 1
ANAPC2 anaphase promoting complex subunit 2
ARR3 arrestin 3, retinal (X-arrestin)
ASB8 ankyrin repeat and SOCS box containing 8
ATAT1 alpha tubulin acetyltransferase 1
ATG10 autophagy related 10
ATP11B ATPase, class VI, type 11B
AXIN1 axin 1
BPIFA1 BPI fold containing family A, member 1
C11ORF80 chromosome 11 open reading frame 80
C1ORF27 chromosome 1 open reading frame 27
C6ORF47 chromosome 6 open reading frame 47
CA5BP1 carbonic anhydrase VB pseudogene 1
CAV3 caveolin 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CROT carnitine O-octanoyltransferase
CXCL9 chemokine (C-X-C motif) ligand 9
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRP2 dystrophin related protein 2
EFNA1 ephrin-A1
FAM153A family with sequence similarity 153, member A
FGGY FGGY carbohydrate kinase domain containing
FRMD8 FERM domain containing 8
FZD2 frizzled class receptor 2
GAST gastrin
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR21 G protein-coupled receptor 21
GPR3 G protein-coupled receptor 3
GRM4 glutamate receptor, metabotropic 4
GTPBP8 GTP-binding protein 8 (putative)
HELLS helicase, lymphoid-specific
HIST3H2A histone cluster 3, H2a
HOMER2 homer scaffolding protein 2
IGFLR1 IGF-like family receptor 1
IL2RG interleukin 2 receptor, gamma
INPP5F inositol polyphosphate-5-phosphatase F
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLK8 kallikrein-related peptidase 8
KPTN kaptin (actin binding protein)
LRRC49 leucine rich repeat containing 49
LUC7L LUC7-like (S. cerevisiae)
LYZL6 lysozyme-like 6
MCOLN1 mucolipin 1
MEFV Mediterranean fever
MYO1A myosin IA
NADSYN1 NAD synthetase 1
NARFL nuclear prelamin A recognition factor-like
NBEAL2 neurobeachin-like 2
NHLRC2 NHL repeat containing 2
NNAT neuronatin
NOL6 nucleolar protein 6 (RNA-associated)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
PLXNA3 plexin A3
POLM polymerase (DNA directed), mu
RABL6 RAB, member RAS oncogene family-like 6
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RECQL4 RecQ protein-like 4
RNF39 ring finger protein 39
RSAD1 radical S-adenosyl methionine domain containing 1
SLC12A9 solute carrier family 12, member 9
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SPAG4 sperm associated antigen 4
SYT13 synaptotagmin XIII
TARBP1 TAR (HIV-1) RNA binding protein 1
TEAD3 TEA domain family member 3
THRB thyroid hormone receptor, beta
TMEM127 transmembrane protein 127
TMEM62 transmembrane protein 62
TRIM58 tripartite motif containing 58
TSC22D4 TSC22 domain family, member 4
TTF2 transcription termination factor, RNA polymerase II
TUBA4B tubulin, alpha 4b
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP19 ubiquitin specific peptidase 19
VASP vasodilator-stimulated phosphoprotein
WDR11 WD repeat domain 11
WDR19 WD repeat domain 19
ZBTB22 zinc finger and BTB domain containing 22
ZNF276 zinc finger protein 276
ZNF671 zinc finger protein 671
ZNF747 zinc finger protein 747
ZNF778 zinc finger protein 778
ZNF816 zinc finger protein 816
ZSWIM1 zinc finger, SWIM-type containing 1