alprenolol-1571 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the alprenolol-1571 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACVRL1 activin A receptor type II-like 1
AIM2 absent in melanoma 2
AMBRA1 autophagy/beclin-1 regulator 1
ANKRD11 ankyrin repeat domain 11
ARID4A AT rich interactive domain 4A (RBP1-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BATF basic leucine zipper transcription factor, ATF-like
C2CD2L C2CD2-like
C2ORF68 chromosome 2 open reading frame 68
C7ORF26 chromosome 7 open reading frame 26
CANT1 calcium activated nucleotidase 1
CCL20 chemokine (C-C motif) ligand 20
CCNT1 cyclin T1
CDHR2 cadherin-related family member 2
CHERP calcium homeostasis endoplasmic reticulum protein
CLDN15 claudin 15
CTBS chitobiase, di-N-acetyl-
CTSZ cathepsin Z
CYB561 cytochrome b561
DIDO1 death inducer-obliterator 1
DRG2 developmentally regulated GTP binding protein 2
DUS2 dihydrouridine synthase 2
E2F1 E2F transcription factor 1
ELMO2 engulfment and cell motility 2
ENO2 enolase 2 (gamma, neuronal)
FAM160B2 family with sequence similarity 160, member B2
FBXW4 F-box and WD repeat domain containing 4
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLG1 golgi glycoprotein 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRK6 G protein-coupled receptor kinase 6
GSS glutathione synthetase
HDAC5 histone deacetylase 5
HEG1 heart development protein with EGF-like domains 1
HELLS helicase, lymphoid-specific
HNF1B HNF1 homeobox B
HTT huntingtin
HYAL2 hyaluronoglucosaminidase 2
IFITM1 interferon induced transmembrane protein 1
IGFBP7 insulin-like growth factor binding protein 7
JRKL JRK-like
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KDM5A lysine (K)-specific demethylase 5A
KIFC1 kinesin family member C1
KLF6 Kruppel-like factor 6
KLHDC4 kelch domain containing 4
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LMAN2L lectin, mannose-binding 2-like
MAGED2 melanoma antigen family D2
MAP4 microtubule-associated protein 4
MAST2 microtubule associated serine/threonine kinase 2
MED16 mediator complex subunit 16
MICALL1 MICAL-like 1
NADK NAD kinase
NEFH neurofilament, heavy polypeptide
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDE8A phosphodiesterase 8A
PNO1 partner of NOB1 homolog (S. cerevisiae)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPCS phosphopantothenoylcysteine synthetase
PTCD1 pentatricopeptide repeat domain 1
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PUS3 pseudouridylate synthase 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD52 RAD52 homolog (S. cerevisiae)
RANBP3 RAN binding protein 3
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RECQL4 RecQ protein-like 4
SEC23IP SEC23 interacting protein
SECISBP2L SECIS binding protein 2-like
SETD4 SET domain containing 4
SH3BP2 SH3-domain binding protein 2
SIDT2 SID1 transmembrane family, member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SMAD3 SMAD family member 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNX13 sorting nexin 13
SOX4 SRY (sex determining region Y)-box 4
SPATA5L1 spermatogenesis associated 5-like 1
SPI1 Spi-1 proto-oncogene
SPN sialophorin
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBCD tubulin folding cofactor D
TCL1A T-cell leukemia/lymphoma 1A
TCTN2 tectonic family member 2
TGOLN2 trans-golgi network protein 2
TK2 thymidine kinase 2, mitochondrial
TMEM8A transmembrane protein 8A
TRA T cell receptor alpha locus
TRIM22 tripartite motif containing 22
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF124 zinc finger protein 124

decreased expression

Symbol Name
AMT aminomethyltransferase
ANAPC2 anaphase promoting complex subunit 2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APOBR apolipoprotein B receptor
ARMC7 armadillo repeat containing 7
ATAD2B ATPase family, AAA domain containing 2B
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BIN2 bridging integrator 2
BORA bora, aurora kinase A activator
C11ORF73 chromosome 11 open reading frame 73
CAPN15 calpain 15
CGRRF1 cell growth regulator with ring finger domain 1
CIDEB cell death-inducing DFFA-like effector b
CIR1 corepressor interacting with RBPJ, 1
COG7 component of oligomeric golgi complex 7
COLGALT2 collagen beta(1-O)galactosyltransferase 2
DCTN4 dynactin 4 (p62)
DDIT3 DNA-damage-inducible transcript 3
DHDDS dehydrodolichyl diphosphate synthase
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DIXDC1 DIX domain containing 1
DNAAF2 dynein, axonemal, assembly factor 2
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
FANCC Fanconi anemia, complementation group C
FBXL6 F-box and leucine-rich repeat protein 6
FBXO5 F-box protein 5
GAB2 GRB2-associated binding protein 2
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GIMAP6 GTPase, IMAP family member 6
GIN1 gypsy retrotransposon integrase 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPKOW G patch domain and KOW motifs
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2IRD1 GTF2I repeat domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HIPK2 homeodomain interacting protein kinase 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITFG1 integrin alpha FG-GAP repeat containing 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
LACTB2 lactamase, beta 2
LARS leucyl-tRNA synthetase
LIMA1 LIM domain and actin binding 1
LRRC37A2 leucine rich repeat containing 37, member A2
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGT1 magnesium transporter 1
MBD5 methyl-CpG binding domain protein 5
MICB MHC class I polypeptide-related sequence B
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MRPL19 mitochondrial ribosomal protein L19
MYL12B myosin, light chain 12B, regulatory
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NCKAP1L NCK-associated protein 1-like
NHLRC2 NHL repeat containing 2
NINJ1 ninjurin 1
NSD1 nuclear receptor binding SET domain protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RFWD3 ring finger and WD repeat domain 3
RHOC ras homolog family member C
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPAP1 RNA polymerase II associated protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
RPP38 ribonuclease P/MRP 38kDa subunit
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
SFMBT1 Scm-like with four mbt domains 1
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLN sarcolipin
SNX15 sorting nexin 15
SNX6 sorting nexin 6
SPA17 sperm autoantigenic protein 17
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TRAF3 TNF receptor-associated factor 3
TRIM45 tripartite motif containing 45
TRIM5 tripartite motif containing 5
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC13 tetratricopeptide repeat domain 13
TTF2 transcription termination factor, RNA polymerase II
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBIAD1 UbiA prenyltransferase domain containing 1
UBQLN4 ubiquilin 4
UFM1 ubiquitin-fold modifier 1
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
ZEB2 zinc finger E-box binding homeobox 2
ZFAND3 zinc finger, AN1-type domain 3
ZNF160 zinc finger protein 160
ZNF426 zinc finger protein 426
ZNF430 zinc finger protein 430
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669