alprenolol-6789 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the alprenolol-6789 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ACRV1 acrosomal vesicle protein 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGFG1 ArfGAP with FG repeats 1
APC adenomatous polyposis coli
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP44 Rho GTPase activating protein 44
ARMC6 armadillo repeat containing 6
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BBS9 Bardet-Biedl syndrome 9
BMP1 bone morphogenetic protein 1
C14ORF79 chromosome 14 open reading frame 79
C17ORF53 chromosome 17 open reading frame 53
C3 complement component 3
CDHR2 cadherin-related family member 2
CHKB choline kinase beta
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNN1 calponin 1, basic, smooth muscle
CNR2 cannabinoid receptor 2 (macrophage)
CRTC1 CREB regulated transcription coactivator 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCTN1 dynactin 1
DENND5B DENN/MADD domain containing 5B
DGCR8 DGCR8 microprocessor complex subunit
DMXL2 Dmx-like 2
DNAH17 dynein, axonemal, heavy chain 17
DUSP10 dual specificity phosphatase 10
EPN1 epsin 1
ERCC2 excision repair cross-complementation group 2
FADS2 fatty acid desaturase 2
FAM155A family with sequence similarity 155, member A
FAM214B family with sequence similarity 214, member B
FBLN1 fibulin 1
FBXL7 F-box and leucine-rich repeat protein 7
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ11292
FLOT1 flotillin 1
FXYD7 FXYD domain containing ion transport regulator 7
GAB1 GRB2-associated binding protein 1
GLB1L galactosidase, beta 1-like
GPNMB glycoprotein (transmembrane) nmb
GREM2 gremlin 2, DAN family BMP antagonist
GRM1 glutamate receptor, metabotropic 1
HDAC5 histone deacetylase 5
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HYI hydroxypyruvate isomerase (putative)
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ING4 inhibitor of growth family, member 4
IQCC IQ motif containing C
ITGB4 integrin, beta 4
KCNIP1 Kv channel interacting protein 1
KIAA0040 KIAA0040
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LAMP3 lysosomal-associated membrane protein 3
LMX1B LIM homeobox transcription factor 1, beta
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MATN1 matrilin 1, cartilage matrix protein
MBNL2 muscleblind-like splicing regulator 2
MBNL3 muscleblind-like splicing regulator 3
MKL1 megakaryoblastic leukemia (translocation) 1
MTMR3 myotubularin related protein 3
MUC3B mucin 3B, cell surface associated
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NUP50 nucleoporin 50kDa
NYNRIN NYN domain and retroviral integrase containing
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PARVA parvin, alpha
PDE4DIP phosphodiesterase 4D interacting protein
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKCA protein kinase C, alpha
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SIPA1 signal-induced proliferation-associated 1
SKIL SKI-like proto-oncogene
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLN sarcolipin
SPN sialophorin
SPTB spectrin, beta, erythrocytic
STARD8 StAR-related lipid transfer (START) domain containing 8
TAPBP TAP binding protein (tapasin)
TBC1D30 TBC1 domain family, member 30
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TIMP3 TIMP metallopeptidase inhibitor 3
TLR1 toll-like receptor 1
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TWISTNB TWIST neighbor
VNN2 vanin 2
ZFX zinc finger protein, X-linked
ZNF137P zinc finger protein 137, pseudogene
ZNF423 zinc finger protein 423
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADGRG2 adhesion G protein-coupled receptor G2
AES amino-terminal enhancer of split
ANXA2P3 annexin A2 pseudogene 3
ARRB1 arrestin, beta 1
ATAD5 ATPase family, AAA domain containing 5
ATF3 activating transcription factor 3
ATOX1 antioxidant 1 copper chaperone
ATP11B ATPase, class VI, type 11B
BAG4 BCL2-associated athanogene 4
C16ORF59 chromosome 16 open reading frame 59
CAPN15 calpain 15
CBR4 carbonyl reductase 4
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CLASP1 cytoplasmic linker associated protein 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPPED1 calcineurin-like phosphoesterase domain containing 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAAF2 dynein, axonemal, assembly factor 2
DVL1 dishevelled segment polarity protein 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ETAA1 Ewing tumor-associated antigen 1
FAM127B family with sequence similarity 127, member B
FAM222B family with sequence similarity 222, member B
FIP1L1 factor interacting with PAPOLA and CPSF1
FLRT3 fibronectin leucine rich transmembrane protein 3
GPR27 G protein-coupled receptor 27
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H4C histone cluster 1, H4c
HOXC8 homeobox C8
ICK intestinal cell (MAK-like) kinase
IFI6 interferon, alpha-inducible protein 6
KIAA0319L KIAA0319-like
KPTN kaptin (actin binding protein)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LYPD3 LY6/PLAUR domain containing 3
MAST3 microtubule associated serine/threonine kinase 3
MGC12488
MORC3 MORC family CW-type zinc finger 3
MVD mevalonate (diphospho) decarboxylase
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NIP7 NIP7, nucleolar pre-rRNA processing protein
NLK nemo-like kinase
NNAT neuronatin
NVL nuclear VCP-like
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCDHB3 protocadherin beta 3
PCOLCE2 procollagen C-endopeptidase enhancer 2
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLA2G12A phospholipase A2, group XIIA
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PRODH proline dehydrogenase (oxidase) 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM42 RNA binding motif protein 42
RCAN3 RCAN family member 3
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGS2 regulator of G-protein signaling 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP7 ribosomal protein L23a pseudogene 7
S100A6 S100 calcium binding protein A6
SETD6 SET domain containing 6
SGK1 serum/glucocorticoid regulated kinase 1
SH2B3 SH2B adaptor protein 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLIT2 slit homolog 2 (Drosophila)
SMAD7 SMAD family member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOBP sine oculis binding protein homolog (Drosophila)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TDRD1 tudor domain containing 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TMEM53 transmembrane protein 53
TNS2 tensin 2
TPST1 tyrosylprotein sulfotransferase 1
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBIAD1 UbiA prenyltransferase domain containing 1
UEVLD UEV and lactate/malate dehyrogenase domains
USP36 ubiquitin specific peptidase 36
VN1R1 vomeronasal 1 receptor 1
ZBTB39 zinc finger and BTB domain containing 39
ZNF134 zinc finger protein 134
ZNF227 zinc finger protein 227
ZNF394 zinc finger protein 394
ZNF442 zinc finger protein 442
ZNF675 zinc finger protein 675
ZNF8 zinc finger protein 8