| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the alprostadil-2938 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABHD6 | abhydrolase domain containing 6 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AREG | amphiregulin |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| AVPI1 | arginine vasopressin-induced 1 |
| AXL | AXL receptor tyrosine kinase |
| BDNF | brain-derived neurotrophic factor |
| BIN1 | bridging integrator 1 |
| BMP6 | bone morphogenetic protein 6 |
| C5AR1 | complement component 5a receptor 1 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD300C | CD300c molecule |
| CD38 | CD38 molecule |
| CD86 | CD86 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHN2 | chimerin 2 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| COL4A2 | collagen, type IV, alpha 2 |
| CREM | cAMP responsive element modulator |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CTSB | cathepsin B |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK4 | dedicator of cytokinesis 4 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| FADS3 | fatty acid desaturase 3 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOSL2 | FOS-like antigen 2 |
| FOXA1 | forkhead box A1 |
| FPR1 | formyl peptide receptor 1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GNLY | granulysin |
| GPR183 | G protein-coupled receptor 183 |
| GRAMD1B | GRAM domain containing 1B |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HOMER1 | homer scaffolding protein 1 |
| HOXA5 | homeobox A5 |
| HPSE | heparanase |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFI30 | interferon, gamma-inducible protein 30 |
| IL11 | interleukin 11 |
| IL1RN | interleukin 1 receptor antagonist |
| INHBA | inhibin, beta A |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JOSD1 | Josephin domain containing 1 |
| KYNU | kynureninase |
| LAMB3 | laminin, beta 3 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| MCAM | melanoma cell adhesion molecule |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MXRA8 | matrix-remodelling associated 8 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| OSM | oncostatin M |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLSCR1 | phospholipid scramblase 1 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRL | prolactin |
| RAB8B | RAB8B, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDC2 | syndecan 2 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SH2D2A | SH2 domain containing 2A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIK1 | salt-inducible kinase 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SKIL | SKI-like proto-oncogene |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter), member 12 |
| SMOX | spermine oxidase |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STAT4 | signal transducer and activator of transcription 4 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THBS1 | thrombospondin 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TKTL1 | transketolase-like 1 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TUBB2A | tubulin, beta 2A class IIa |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| Symbol | Name |
|---|---|
| ANKRD55 | ankyrin repeat domain 55 |
| APOL6 | apolipoprotein L, 6 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BIN2 | bridging integrator 2 |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| CCDC86 | coiled-coil domain containing 86 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNA1 | cyclin A1 |
| CD69 | CD69 molecule |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CECR5 | cat eye syndrome chromosome region, candidate 5 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DEAF1 | DEAF1 transcription factor |
| DENND2D | DENN/MADD domain containing 2D |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EXOSC5 | exosome component 5 |
| FAM188A | family with sequence similarity 188, member A |
| FAM216A | family with sequence similarity 216, member A |
| FAR2 | fatty acyl CoA reductase 2 |
| FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
| FLT3 | fms-related tyrosine kinase 3 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| GSAP | gamma-secretase activating protein |
| HDAC9 | histone deacetylase 9 |
| HMGA2 | high mobility group AT-hook 2 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOPX | HOP homeobox |
| IFRD2 | interferon-related developmental regulator 2 |
| IRF8 | interferon regulatory factor 8 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIAA0020 | KIAA0020 |
| KIAA0930 | KIAA0930 |
| KIF21B | kinesin family member 21B |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| OSBPL1A | oxysterol binding protein-like 1A |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PPAN | peter pan homolog (Drosophila) |
| PRDM13 | PR domain containing 13 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PUS1 | pseudouridylate synthase 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RNF144A | ring finger protein 144A |
| RPIA | ribose 5-phosphate isomerase A |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RUVBL1 | RuvB-like AAA ATPase 1 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SRM | spermidine synthase |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STRA13 | stimulated by retinoic acid 13 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TEC | tec protein tyrosine kinase |
| TLR2 | toll-like receptor 2 |
| TNF | tumor necrosis factor |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 |
| UNG | uracil-DNA glycosylase |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR12 | WD repeat domain 12 |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| WT1 | Wilms tumor 1 |
| WT1-AS | WT1 antisense RNA |
| ZNF593 | zinc finger protein 593 |
| ZNF692 | zinc finger protein 692 |
