| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the alprostadil-4099 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGRP | agouti related neuropeptide |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BMP2 | bone morphogenetic protein 2 |
| BMP4 | bone morphogenetic protein 4 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C3 | complement component 3 |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CREM | cAMP responsive element modulator |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYTH3 | cytohesin 3 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIAPH2 | diaphanous-related formin 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DMBT1 | deleted in malignant brain tumors 1 |
| DST | dystonin |
| DUSP1 | dual specificity phosphatase 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EPAS1 | endothelial PAS domain protein 1 |
| F9 | coagulation factor IX |
| FLJ11292 | |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMD4B | FERM domain containing 4B |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GK | glycerol kinase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| IL11 | interleukin 11 |
| IL1RN | interleukin 1 receptor antagonist |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| INSL4 | insulin-like 4 (placenta) |
| INSR | insulin receptor |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KLHL18 | kelch-like family member 18 |
| KRT17 | keratin 17, type I |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIPG | lipase, endothelial |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP7 | microtubule-associated protein 7 |
| MDM4 | MDM4, p53 regulator |
| NF1 | neurofibromin 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PAPPA2 | pappalysin 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PHF14 | PHD finger protein 14 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PLD2 | phospholipase D2 |
| PLK4 | polo-like kinase 4 |
| POSTN | periostin, osteoblast specific factor |
| PRKCI | protein kinase C, iota |
| PTGES | prostaglandin E synthase |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAP2B | RAP2B, member of RAS oncogene family |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS4 | regulator of G-protein signaling 4 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RUNDC3A | RUN domain containing 3A |
| RYR2 | ryanodine receptor 2 (cardiac) |
| S100P | S100 calcium binding protein P |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLA | Src-like-adaptor |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC39A9 | solute carrier family 39, member 9 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SP1 | Sp1 transcription factor |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STC1 | stanniocalcin 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TGFB2 | transforming growth factor, beta 2 |
| THBD | thrombomodulin |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TRIM29 | tripartite motif containing 29 |
| TXNRD3 | thioredoxin reductase 3 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| ZMAT5 | zinc finger, matrin-type 5 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| ALB | albumin |
| AMH | anti-Mullerian hormone |
| ANKRD7 | ankyrin repeat domain 7 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| AURKC | aurora kinase C |
| BMP15 | bone morphogenetic protein 15 |
| BRSK2 | BR serine/threonine kinase 2 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CASS4 | Cas scaffolding protein family member 4 |
| CCDC102B | coiled-coil domain containing 102B |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD82 | CD82 molecule |
| CDHR2 | cadherin-related family member 2 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CXORF21 | chromosome X open reading frame 21 |
| CYB5R2 | cytochrome b5 reductase 2 |
| ENO3 | enolase 3 (beta, muscle) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC6B | exocyst complex component 6B |
| FAM186A | family with sequence similarity 186, member A |
| FBXO22 | F-box protein 22 |
| FBXO31 | F-box protein 31 |
| FGL1 | fibrinogen-like 1 |
| FLCN | folliculin |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H3I | histone cluster 1, H3i |
| HOXA6 | homeobox A6 |
| HRH2 | histamine receptor H2 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| ICOS | inducible T-cell co-stimulator |
| IFNA17 | interferon, alpha 17 |
| IFT140 | intraflagellar transport 140 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM5C | lysine (K)-specific demethylase 5C |
| KRT15 | keratin 15, type I |
| LENEP | lens epithelial protein |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAGEA3 | melanoma antigen family A3 |
| MGP | matrix Gla protein |
| MTSS1L | metastasis suppressor 1-like |
| NLGN1 | neuroligin 1 |
| NOL10 | nucleolar protein 10 |
| NOL4 | nucleolar protein 4 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPPB | natriuretic peptide B |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE8B | phosphodiesterase 8B |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLBD1 | phospholipase B domain containing 1 |
| PODXL2 | podocalyxin-like 2 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| RAPSN | receptor-associated protein of the synapse |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| SCAI | suppressor of cancer cell invasion |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD1A | SET domain containing 1A |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TENM4 | teneurin transmembrane protein 4 |
| TMEM212 | transmembrane protein 212 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TSGA10 | testis specific, 10 |
| TUBA3C | tubulin, alpha 3c |
| WDR4 | WD repeat domain 4 |
| ZIC3 | Zic family member 3 |
| ZNF222 | zinc finger protein 222 |
| ZNF510 | zinc finger protein 510 |
| ZNF549 | zinc finger protein 549 |
| ZNF749 | zinc finger protein 749 |
| ZNF767P | zinc finger family member 767, pseudogene |
