| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alprostadil-4179 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CDC42 | cell division cycle 42 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CHI3L2 | chitinase 3-like 2 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLEC1A | C-type lectin domain family 1, member A |
| CLTA | clathrin, light chain A |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTSS | cathepsin S |
| CYTH4 | cytohesin 4 |
| DCTN2 | dynactin 2 (p50) |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DUOX1 | dual oxidase 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM149A | family with sequence similarity 149, member A |
| FAM49A | family with sequence similarity 49, member A |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGF2 | fibroblast growth factor 2 (basic) |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GPR85 | G protein-coupled receptor 85 |
| HLF | hepatic leukemia factor |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOXB3 | homeobox B3 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL1R2 | interleukin 1 receptor, type II |
| IL1RN | interleukin 1 receptor antagonist |
| INE1 | inactivation escape 1 (non-protein coding) |
| IQCA1 | IQ motif containing with AAA domain 1 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIAA1109 | KIAA1109 |
| KRT14 | keratin 14, type I |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LDB3 | LIM domain binding 3 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LOXL2 | lysyl oxidase-like 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MID1 | midline 1 |
| MYO7A | myosin VIIA |
| MYOZ1 | myozenin 1 |
| NAG18 | NAG18 mRNA |
| NCAM1 | neural cell adhesion molecule 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NIPAL3 | NIPA-like domain containing 3 |
| NOX1 | NADPH oxidase 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OCA2 | oculocutaneous albinism II |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDAP1 | PDGFA associated protein 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDLIM3 | PDZ and LIM domain 3 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLXNB1 | plexin B1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SEMG2 | semenogelin II |
| SIRPB1 | signal-regulatory protein beta 1 |
| SLAMF7 | SLAM family member 7 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SPACA1 | sperm acrosome associated 1 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYN3 | synapsin III |
| TDRD12 | tudor domain containing 12 |
| TEK | TEK tyrosine kinase, endothelial |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VSNL1 | visinin-like 1 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACYP2 | acylphosphatase 2, muscle type |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADCK4 | aarF domain containing kinase 4 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ARRB1 | arrestin, beta 1 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C3 | complement component 3 |
| C3AR1 | complement component 3a receptor 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CD34 | CD34 molecule |
| CFAP70 | cilia and flagella associated protein 70 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLDN1 | claudin 1 |
| CLDN15 | claudin 15 |
| CLEC4E | C-type lectin domain family 4, member E |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DUSP13 | dual specificity phosphatase 13 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EPX | eosinophil peroxidase |
| ERCC2 | excision repair cross-complementation group 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FBXO2 | F-box protein 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FFAR2 | free fatty acid receptor 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR27 | G protein-coupled receptor 27 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4E | histone cluster 1, H4e |
| HOXB2 | homeobox B2 |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNIP1 | Kv channel interacting protein 1 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA1024 | KIAA1024 |
| KITLG | KIT ligand |
| KLHL25 | kelch-like family member 25 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MEFV | Mediterranean fever |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MX1 | MX dynamin-like GTPase 1 |
| NLGN1 | neuroligin 1 |
| NME5 | NME/NM23 family member 5 |
| NOL10 | nucleolar protein 10 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OLFML2A | olfactomedin-like 2A |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OVOL1 | ovo-like zinc finger 1 |
| PCDHB13 | protocadherin beta 13 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLXNB3 | plexin B3 |
| POPDC3 | popeye domain containing 3 |
| PORCN | porcupine homolog (Drosophila) |
| PQLC2 | PQ loop repeat containing 2 |
| PRKCE | protein kinase C, epsilon |
| RASIP1 | Ras interacting protein 1 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RND1 | Rho family GTPase 1 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNCAIP | synuclein, alpha interacting protein |
| SOAT2 | sterol O-acyltransferase 2 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STK11 | serine/threonine kinase 11 |
| TAS2R4 | taste receptor, type 2, member 4 |
| TEX40 | testis expressed 40 |
| TLR2 | toll-like receptor 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TMPRSS2 | transmembrane protease, serine 2 |
| TRIM25 | tripartite motif containing 25 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UPP1 | uridine phosphorylase 1 |
| VASH2 | vasohibin 2 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZNF34 | zinc finger protein 34 |
| ZNF350 | zinc finger protein 350 |
| ZNF532 | zinc finger protein 532 |
