| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alprostadil-6555 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AEN | apoptosis enhancing nuclease |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANGPTL4 | angiopoietin-like 4 |
| ANXA10 | annexin A10 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARL14 | ADP-ribosylation factor-like 14 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BRD4 | bromodomain containing 4 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CREM | cAMP responsive element modulator |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CSNK1E | casein kinase 1, epsilon |
| CTAGE5 | CTAGE family, member 5 |
| CTH | cystathionine gamma-lyase |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EFNA3 | ephrin-A3 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPHA1 | EPH receptor A1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GRM1 | glutamate receptor, metabotropic 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GTPBP4 | GTP binding protein 4 |
| HAP1 | huntingtin-associated protein 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H3G | histone cluster 1, H3g |
| HOXC10 | homeobox C10 |
| IL11 | interleukin 11 |
| IL1R2 | interleukin 1 receptor, type II |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGB5 | integrin, beta 5 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KRT17 | keratin 17, type I |
| LIMK1 | LIM domain kinase 1 |
| LMNB1 | lamin B1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MAP7 | microtubule-associated protein 7 |
| MXD4 | MAX dimerization protein 4 |
| NCOA2 | nuclear receptor coactivator 2 |
| NPEPL1 | aminopeptidase-like 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PC | pyruvate carboxylase |
| PCDH7 | protocadherin 7 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PKP1 | plakophilin 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTGES | prostaglandin E synthase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTHLH | parathyroid hormone-like hormone |
| RAB2A | RAB2A, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| S100P | S100 calcium binding protein P |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SMOX | spermine oxidase |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STC1 | stanniocalcin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNJ1 | synaptojanin 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBL1X | transducin (beta)-like 1X-linked |
| TCF4 | transcription factor 4 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRIM29 | tripartite motif containing 29 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| TXNRD3 | thioredoxin reductase 3 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| URI1 | URI1, prefoldin-like chaperone |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AMT | aminomethyltransferase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARRB2 | arrestin, beta 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BEX1 | brain expressed, X-linked 1 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CBX4 | chromobox homolog 4 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CLDN14 | claudin 14 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CORO1A | coronin, actin binding protein, 1A |
| CTGF | connective tissue growth factor |
| CYB5R2 | cytochrome b5 reductase 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC5 | exocyst complex component 5 |
| FAR2 | fatty acyl CoA reductase 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| GALK1 | galactokinase 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR21 | G protein-coupled receptor 21 |
| GPR3 | G protein-coupled receptor 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GTF2I | general transcription factor IIi |
| HIST1H3C | histone cluster 1, H3c |
| HOXC4 | homeobox C4 |
| IFNA14 | interferon, alpha 14 |
| IFNB1 | interferon, beta 1, fibroblast |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITGA10 | integrin, alpha 10 |
| KIAA0355 | KIAA0355 |
| KIAA1549L | KIAA1549-like |
| KIZ | kizuna centrosomal protein |
| KLHL25 | kelch-like family member 25 |
| KRT86 | keratin 86, type II |
| LMTK1 | lemur tail kinase 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MANBA | mannosidase, beta A, lysosomal |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDFI | MyoD family inhibitor |
| MMP13 | matrix metallopeptidase 13 |
| MT1M | metallothionein 1M |
| MUC3B | mucin 3B, cell surface associated |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NDNF | neuron-derived neurotrophic factor |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NPY1R | neuropeptide Y receptor Y1 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PARPBP | PARP1 binding protein |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLK2 | polo-like kinase 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRR4 | proline rich 4 (lacrimal) |
| RGS20 | regulator of G-protein signaling 20 |
| RNF146 | ring finger protein 146 |
| RNF2 | ring finger protein 2 |
| RNF38 | ring finger protein 38 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SETBP1 | SET binding protein 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SLN | sarcolipin |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF34 | zinc finger protein 34 |
| ZNF385D | zinc finger protein 385D |
| ZNF573 | zinc finger protein 573 |
