| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the alprostadil-6571 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ACOT7 | acyl-CoA thioesterase 7 |
| ACTB | actin, beta |
| AKAP1 | A kinase (PRKA) anchor protein 1 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ANGPTL4 | angiopoietin-like 4 |
| ANTXR1 | anthrax toxin receptor 1 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CALD1 | caldesmon 1 |
| CALU | calumenin |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CLDN3 | claudin 3 |
| COPS8 | COP9 signalosome subunit 8 |
| CPQ | carboxypeptidase Q |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CTH | cystathionine gamma-lyase |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| EIF5A | eukaryotic translation initiation factor 5A |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENO1 | enolase 1, (alpha) |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FH | fumarate hydratase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FUS | FUS RNA binding protein |
| FZD8 | frizzled class receptor 8 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| GDI2 | GDP dissociation inhibitor 2 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPHN | gephyrin |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| IL1RAP | interleukin 1 receptor accessory protein |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KIAA0922 | KIAA0922 |
| KLF6 | Kruppel-like factor 6 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAGEF1 | melanoma antigen family F1 |
| MAT2A | methionine adenosyltransferase II, alpha |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial |
| MED6 | mediator complex subunit 6 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MPZL1 | myelin protein zero-like 1 |
| MSH6 | mutS homolog 6 |
| NCK1 | NCK adaptor protein 1 |
| NMD3 | NMD3 ribosome export adaptor |
| NOTCH2 | notch 2 |
| OCRL | oculocerebrorenal syndrome of Lowe |
| PLEC | plectin |
| POLR2E | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa |
| PPIF | peptidylprolyl isomerase F |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PRNP | prion protein |
| PRPF4 | pre-mRNA processing factor 4 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSEN1 | presenilin 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RNF24 | ring finger protein 24 |
| RRM1 | ribonucleotide reductase M1 |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SH2D4A | SH2 domain containing 4A |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SPAG9 | sperm associated antigen 9 |
| STC1 | stanniocalcin 1 |
| STIP1 | stress-induced phosphoprotein 1 |
| STK4 | serine/threonine kinase 4 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| SYPL1 | synaptophysin-like 1 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| TAGLN2 | transgelin 2 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM194A | transmembrane protein 194A |
| TMEM230 | transmembrane protein 230 |
| TSPAN4 | tetraspanin 4 |
| UBE2N | ubiquitin-conjugating enzyme E2N |
| UBE4B | ubiquitination factor E4B |
| USB1 | U6 snRNA biogenesis 1 |
| USP34 | ubiquitin specific peptidase 34 |
| WDR1 | WD repeat domain 1 |
| YIPF5 | Yip1 domain family, member 5 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| ZNF148 | zinc finger protein 148 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACVR2B | activin A receptor, type IIB |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALPK1 | alpha-kinase 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BBC3 | BCL2 binding component 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCNE1 | cyclin E1 |
| CCNT1 | cyclin T1 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CENPT | centromere protein T |
| CLCA1 | chloride channel accessory 1 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNPY3 | canopy FGF signaling regulator 3 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CST4 | cystatin S |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DOCK1 | dedicator of cytokinesis 1 |
| EGF | epidermal growth factor |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FOXC1 | forkhead box C1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H4C | histone cluster 1, H4c |
| HLX | H2.0-like homeobox |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KDM4D | lysine (K)-specific demethylase 4D |
| KRT15 | keratin 15, type I |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LYRM9 | LYR motif containing 9 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MCC | mutated in colorectal cancers |
| MED23 | mediator complex subunit 23 |
| MMP13 | matrix metallopeptidase 13 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUC3A | mucin 3A, cell surface associated |
| MXD3 | MAX dimerization protein 3 |
| MYL5 | myosin, light chain 5, regulatory |
| MYO15A | myosin XVA |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOTCH4 | notch 4 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PCDH12 | protocadherin 12 |
| PDE12 | phosphodiesterase 12 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODNL1 | podocan-like 1 |
| PRR15L | proline rich 15-like |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| PTX3 | pentraxin 3, long |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF122 | ring finger protein 122 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SAMD9 | sterile alpha motif domain containing 9 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNTA1 | syntrophin, alpha 1 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPRR2B | small proline-rich protein 2B |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TCTN2 | tectonic family member 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMC5 | transmembrane channel-like 5 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRAF2 | TNF receptor-associated factor 2 |
| TSPAN15 | tetraspanin 15 |
| TUBA3C | tubulin, alpha 3c |
| UNC13A | unc-13 homolog A (C. elegans) |
| WFDC2 | WAP four-disulfide core domain 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
